2-pyridinemethanol, 4-methoxy-3-methyl-

2-Pyridyl methanol, 4-methoxy-3-methyl, its physical properties are as follows:
This substance may be in the state of white to light yellow crystalline powder, and it has a specific morphology. Under normal temperature and pressure, its texture is relatively stable and does not change easily.
When it comes to melting point, it is roughly within a certain range. This value is crucial for determining the purity and characteristics of the substance. Determination of melting point is one of the important means to identify this substance.
In terms of solubility, it may exhibit specific solubility characteristics in common organic solvents. In some polar solvents, such as ethanol, the solubility may be certain, while in non-polar solvents, such as n-hexane, the solubility may be very small. This difference in solubility is also an important physical property, and it needs to be considered in detail when separating, purifying and applying this substance.
Furthermore, its density is also an important physical parameter. The value of density reflects the mass of the substance in a unit volume, and is indispensable for accurate measurement and consideration of its mixing with other substances.
Its refractive index also has a specific value, which has certain reference value in the study of optical properties and the detection of material purity.
In summary, the above physical properties of 2-pyridyl methanol and 4-methoxy-3-methyl are of great significance in chemical research, industrial production and related application fields, and can help researchers, producers, etc. better understand and use this substance.

4-Methoxy-3-methyl-2-pyridyl methanol, this substance has many unique chemical properties. In its molecular structure, the pyridine ring is the core, and there are methanol groups, methoxy groups and methyl groups on the side, which deeply affects its properties.
In terms of physical properties, it is usually in a solid state, and its melting and boiling point is relatively high due to the existence of hydrogen bonds and van der Waals forces between molecules. In view of the existence of pyridine rings and methoxy groups, this substance has certain solubility in some organic solvents, such as ethanol and acetone, which can interact with solvent molecules, but it is difficult to dissolve in water because its polarity does not match that of water.
Chemically, methanol groups are active and can participate in esterification reactions. In the case of carboxylic acids or anhydrides, with the help of catalysts, corresponding ester compounds can be formed. In this process, the hydrogen atom of the alcohol hydroxyl group is substituted by the acyl group. The pyridine ring is basic, and the lone pair electrons on the nitrogen atom can bind protons, which can react with acids to form salts. And the pyridine ring can undergo electrophilic substitution reaction. Due to the uneven distribution of electron cloud density on the ring, specific positions are easily attacked by electrophilic reagents, but the reaction conditions are more severe than those of the benzene ring. In addition, methoxy groups are the power supply sub-groups, which will affect the electron cloud density distribution of the pyridine ring, thereby changing the substitution reaction activity and check point selectivity. Methyl groups are relatively stable, but they These chemical properties make it widely used in the field of organic synthesis and can be used as a key intermediate for the creation of various drugs, functional materials, and so on.

2-Pyridyl methanol, 4-methoxy-3-methyl, this substance has a wide range of uses. In the field of medicine, it is often an important intermediate for the synthesis of a variety of drugs. Due to its specific chemical structure and activity, it can participate in the construction of drug molecules, which is of great significance for improving drug efficacy and improving drug properties. For example, in the synthesis of some nervous system drugs, it can be used as a key starting material. After a series of reactions, it can accurately construct molecular structures with specific pharmacological activities, helping drugs to better act on nervous system targets.
In the chemical industry, it also plays an important role. It can be used to prepare special functional materials, such as some materials with specific adsorption or catalytic properties. Due to its structural properties, it can regulate the microstructure and properties of materials during the material synthesis process. For example, when preparing porous materials for specific gas adsorption, its participation can change the pore size and surface properties of the material, and enhance the adsorption capacity of specific gases.
In the field of organic synthesis, it is an indispensable reagent. It can participate in many organic reactions, such as esterification reactions, substitution reactions, etc. Through ingenious design of reaction routes, complex organic molecules can be constructed based on them. In fragrance synthesis, unique structural fragments can be introduced with the help of its reaction, endowing fragrances with special aroma and stability, and improving the quality and application range of fragrances.

To prepare 2-pyridyl methanol, 4-methoxy-3-methyl, the following preparation method can be used.
First take an appropriate amount of 4-methoxy-3-methylpyridine as the starting material. This raw material can be obtained from the corresponding pyridine derivative through methoxylation and methylation steps. For methoxylation, a suitable methoxylation reagent, such as dimethyl sulfate and potassium carbonate, can be selected. In a suitable solvent, heat and stir to introduce methoxy at a specific position on the pyridine ring. Methylation step, iodomethane and strong base can be used to react at a low temperature environment to ensure that the methyl group is precisely connected to the target check point. < Br >
After 4-methoxy-3-methylpyridine is obtained, it is reacted with a suitable reducing agent to prepare 2-pyridine methanol derivatives. If the sodium borohydride-zinc chloride system is used, this system can gently reduce the carbonyl group of the 2-position of the pyridine ring to the methanol group in an organic solvent such as methanol. During the reaction, the temperature should be controlled moderately and stirred evenly to ensure a smooth reaction.
The Grignard reagent method can also be used. First, a Grignard reagent containing a suitable substituent is prepared and reacted with the corresponding pyridinium aldehyde. After the reaction is completed, the product of 2-pyridyl methanol and 4-methoxy-3-methyl can be obtained through post-treatment steps such as hydrolysis. During the post-treatment process, attention should be paid to separation and purification, and extraction, column chromatography and other means can be used to obtain pure products.
During the preparation process, the reaction conditions of each step, such as temperature, time, and reagent dosage, need to be finely regulated to make the reaction proceed efficiently, and the product yield and purity are excellent.

I don't know if 2-pyridyl methanol, 4-methoxy-3-methyl are in the market price range. This is a fine chemical, and its price is affected by many factors.
First, the purity is related to the price. If the purity is very high, reaching the scientific research level, there are very few impurities, and the preparation is difficult, the price will be high; if the purity is slightly lower, it will be used for general industrial purposes, and the price will be slightly lower.
Second, the market supply and demand have a great impact. If there are many people who want it, but the supply is limited, the so-called "rare is expensive", the price will rise; if the supply exceeds the demand, merchants may reduce the price.
Third, the simple preparation process also plays a role. If the preparation requires complex steps, special raw materials or harsh conditions, the cost increases and the price is also high; if the process is relatively simple, the cost decreases and the price also decreases.
Fourth, the pricing of different merchants is different. Large merchants may have different prices due to scale effects and low costs, but brand factors may cause different prices; small merchants may have different prices due to cost considerations and competitive strategies.
And because I do not know the current market details, it is difficult to determine the price range. You can consult the chemical trading platform and chemical raw material suppliers, or you can get the exact price.