2 Pyridinemethanamine 6 Methoxy
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinemethanamine, 6-methoxy-

    Specifications

    HS Code

    179595

    Chemical Formula C8H12N2O
    Molar Mass 152.194 g/mol
    Appearance Solid (likely white or off - white, but color may vary depending on purity)
    Solubility In Water Limited solubility, may be sparingly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, methanol, dichloromethane

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    Frequently Asked Questions

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    2-Pyridinemethanamine, what are the physical properties of 6-methoxy-
    2-Pyridylmethylamine, 6-methoxy, is also an organic compound. Its physical properties are quite important, let me talk about them one by one.
    Looking at its appearance, under room temperature and pressure, it is either a solid state or a liquid state, depending on its specific crystalline form and intermolecular forces. If the molecules are arranged in an orderly manner and have strong interactions, they tend to be solid; conversely, if the intermolecular forces are weak and the movement is relatively free, they will be in a liquid state.
    As for the melting point, the melting point is the temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound is determined by its molecular structure. There are hydrogen bonds, van der Waals forces and other interactions between molecules, and the strength of these interactions affects the melting point. If the interaction between molecules is strong, it requires more heat to obtain enough energy for its solid molecules to become liquid, so the melting point is higher; otherwise, it is lower. The same is true for the boiling point, which is the temperature when the liquid state changes to the gaseous state. When the temperature rises, the molecule obtains enough energy to overcome the intermolecular force, and escapes the liquid surface to become a gaseous state.
    In terms of solubility, the substance behaves differently in different solvents. In polar solvents such as water, if the molecule has a polar group, it can form hydrogen bonds or other interactions with water molecules, it can be partially dissolved; however, if the non-polar part accounts for a large proportion and the force of interaction with water molecules is weak, it is difficult to dissolve in water. In non-polar solvents such as organic solvents, if the molecular structure is similar to that of the solvent and follows the principle of "similar miscibility", it can be better dissolved.
    Density is also one of its physical properties. Density is related to the mass of the substance per unit volume, and is related to the molecular weight and the degree of intermolecular packing. If the molecular mass is large and the packing is tight, the density is larger; vice versa. This property is crucial in the separation and mixing of substances.
    To sum up, the physical properties of 2-pyridylamine and 6-methoxy group, such as appearance, melting point, solubility, density, etc., are determined by their molecular structure, and are of great significance in chemical research, industrial production and many other fields.
    2-Pyridinemethanamine, what are the chemical properties of 6-methoxy-
    The chemical properties of 2-pyridylmethylamine and 6-methoxy are particularly important. This compound is basic and can form salts with acids due to the presence of amino groups. Its methoxy group affects the electron cloud distribution and spatial structure of the molecule.
    In terms of reactivity, amino groups can participate in nucleophilic substitution, such as reacting with halogenated hydrocarbons to generate new carbon-nitrogen bonds. Pyridine rings are also reactive and can undergo electrophilic substitution under specific conditions, but their activity is slightly lower than that of benzene rings. The electron cloud density on the ring decreases due to the electronegativity of nitrogen atoms. < Br >
    Its solubility, due to the presence of polar amino and methoxy groups, may have a certain solubility in polar solvents such as alcohol and water (depending on the specific influence of the substituent). In terms of stability, it is still stable at room temperature and pressure, but may change when exposed to strong oxidizing agents, strong acids and bases. When heated, it may decompose or rearrange, depending on specific conditions.
    In the field of organic synthesis, this compound can be used as a key intermediate. With its activity of amino groups and pyridine rings, complex organic molecules can be constructed, which has potential uses in many fields such as medicinal chemistry and materials science.
    2-Pyridinemethanamine, what is the main use of 6-methoxy-
    2-Pyridylmethylamine, 6-methoxy This substance has a wide range of uses. In the field of medicine, it is an important intermediate in organic synthesis and can be used to create a variety of drugs. For example, when developing drugs related to the nervous system, by modifying and modifying its structure, compounds with specific pharmacological activities can be obtained, or it can help relieve some neurological diseases, such as pain and anxiety.
    In the chemical industry, it also plays a key role in the synthesis of fine chemicals. With its special chemical structure and reactivity, it can participate in many organic reactions and be used to prepare materials with unique properties, such as polymer materials with special optical and electrical properties. These materials have important applications in electronic devices, optical instruments, etc.
    In addition, in the field of agricultural chemistry, it may be possible to develop new pesticides based on it. Using its impact on specific biological activities, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed, helping to improve crop yield and quality, while reducing the harm to the ecological environment. In short, 2-pyridylamine and 6-methoxy have shown important value in many fields and play an indispensable role in promoting the development of related industries.
    2-Pyridinemethanamine, what are the synthesis methods of 6-methoxy-
    To prepare 2-pyridylmethylamine and 6-methoxy group, the following methods can be followed.
    First, 6-methoxy-2-pyridylcarboxylic acid is used as the starting material. The acid is first reacted cautiously at low temperature with a suitable reducing agent, such as lithium aluminum hydride, in an anhydrous organic solvent, such as anhydrous tetrahydrofuran. The strong reducing property of lithium aluminum hydride can convert the carboxyl group to hydroxymethyl group, and then further reduce it to methyl group, so as to obtain the target product. This process requires strict temperature control, and after the reaction is completed, the excess lithium aluminum hydride needs to be carefully handled to prevent accidents. < Br >
    Second, use 6-methoxy-2-pyridine formaldehyde as raw material. Take this aldehyde and ammonia and suitable reducing agents, such as sodium cyanoborohydride, and react in alcoholic solvents such as methanol. The aldehyde group and Mr. ammonia form an imine intermediate, and sodium cyanoborohydride gently reduces this intermediate, and the product of 2-pyridine methylamine and 6-methoxy can be obtained. This approach is relatively mild, but attention needs to be paid to the purity of the raw material and the regulation of the reaction conditions to obtain high yields.
    Third, if 6-methoxy-2-halopyridine is used as the starting material. It can be reacted with nucleophiles, such as sodium azide, in an appropriate solvent, such as dimethylformamide, to form 6-methoxy-2-pyridine azide. After reduction, such as by triphenylphosphine and water system, the azide group is converted into an amino group to obtain the target product. In this process, azide is dangerous and the operation needs to be extra cautious.
    The above methods have their own advantages and disadvantages. When implementing, it should be carefully selected according to the availability of raw materials, the difficulty of reaction conditions and the purity requirements of the product.
    2-Pyridinemethanamine, 6-methoxy- What are the precautions in storage and transportation?
    When storing and transporting 2-pyridylmethylamine, 6-methoxy, there are many key precautions that need to be taken with care.
    First, when storing, you should choose a cool, dry and well-ventilated place. Because it may be quite sensitive to moisture and heat, if it is placed in a warm and humid place, it may cause changes in the properties of the substance, and even cause chemical reactions, which will damage its quality and purity. Just like the ancient people hid things, you also know to look for the dry and cool cellar to prevent the objects from spoiling.
    Second, the packaging must be tight. It needs to be contained in a suitable container to ensure that it is sealed without leakage, so as to prevent contact with outside air, moisture, etc. This is like the ancients sealing fine wine, sealing the mouth of the altar with mud, so that the smell of wine does not leak out, and the smell of wine can last for a long time. If the packaging is not strict, the substance may react with the components in the air, affecting its chemical properties.
    Third, during transportation, avoid violent vibration and collision. The structure of this substance may not be stable, excessive vibration and collision, or cause its internal structure to change, causing danger. Just like transporting fragile porcelain, it needs to be moved slowly and properly protected.
    Fourth, storage and transportation should be away from fire, heat and various oxidants. This substance may be flammable or easily react with oxidizing agents. Once it is close to the source of fire, or when it encounters oxidizing agents, it will be like dry firewood near the fire, which can easily cause serious accidents such as combustion and explosion.
    In short, the storage and transportation of 2-pyridylamine and 6-methoxy groups requires the attention and care of the ancients to ensure their safety and quality.