2-pyridineethanol

2-Pyridyl ethanol is also an organic compound. It has many unique chemical properties.
Looking at its physical properties, at room temperature, 2-pyridyl ethanol is a colorless to light yellow liquid with a slightly special odor. Its boiling point is quite high, about 270 ° C. Due to the hydrogen bonding between molecules, the attractive force between molecules is enhanced, and more energy is required to boil it. And its density is slightly higher than that of water, about 1.12g/cm ³. It has a certain solubility in water. Because the molecule contains hydroxyl groups, it can form hydrogen bonds with water.
On chemical activity, the pyridine ring in 2-pyridyl ethanol interacts with the ethanol group. The pyridine ring is aromatic, and its nitrogen atom is weakly basic, which can react with acids to form pyridine salts. The hydroxyl group of the ethanol group can participate in a variety of reactions. For example, esterification reactions can occur, and ester compounds can be formed with carboxylic acids under acid catalysis. It can also be oxidized. If treated with an appropriate oxidant, the hydroxyl group can be oxidized to an aldehyde group or even a carboxyl group. At the same time, electrophilic substitution reactions can occur on the pyridine ring. Due to the electronegativity of the nitrogen atom on the pyridine ring, the electron cloud density distribution on the ring is uneven, and the substitution reaction mostly occurs in the β-position of the pyridine ring.
2 -pyridyl ethanol has important uses in medicine, pesticides, materials and other fields due to its unique In the field of medicine, it can be used as a drug synthesis intermediate; in the field of materials, it can participate in the synthesis of polymer materials with special properties.

2-Pyridyl ethanol, this substance has a wide range of uses. In the field of medicine, it is an important intermediate. The synthesis of many drugs depends on its participation, such as some nervous system drugs, which use 2-pyridyl ethanol to build a specific chemical structure to help the drug reach the targeted effect and improve the efficacy. In the chemical industry, it is a raw material for the preparation of surfactants. The prepared surfactant has good emulsification and dispersion properties, and can increase the stability and use effect of the product in detergents and cosmetics. In the field of organic synthesis, it is a key building block for the construction of complex pyridine derivatives. Due to its properties of pyridine ring and ethanol group, it can participate in a variety of reactions, such as nucleophilic substitution, oxidation reactions, etc., which assist chemists in synthesizing organic compounds with special functions, such as new photoelectric materials, and contribute to the development of materials science. In the fragrance industry, it can chemically react to produce unique fragrance substances, giving products a pleasant aroma, and playing an important role in the preparation of perfumes and food flavors. In short, 2-pyridyl ethanol plays an indispensable role in many fields, promoting technological innovation and product upgrading in various industries.

The method of making 2-pyridyl ethanol has been explored by many sages in the past, but now it is the general idea of Jun Chen.
First, pyridine is used as the base to combine it with ethylene oxide. In a reaction kettle with suitable temperature and pressure, pyridine meets ethylene oxide, and the two happily meet. With the wonder of nucleophilic substitution, the ring of ethylene oxide is opened, and the nitrogen atom on the pyridine ring exerts a nucleophilic force, which is connected to one end of ethylene oxide, and the other end is supported by hydroxyl groups, so it becomes 2-pyridyl ethanol. The raw materials in this way are common and easy to be induced, but the control of the reaction is fine, the degree of temperature and pressure is slightly poor, or by-production is produced, which hinders the main production.
Second, start with 2-pyridyl formaldehyde, and obtain it by reduction. Take 2-pyridyl formaldehyde, place it in a suitable reaction system, and select a good reducing agent, such as sodium borohydride or lithium aluminum hydride. Sodium borohydride is mild and effective. In alcoholic solvents, it can make the aldehyde group of 2-pyridyl formaldehyde docile and change into a hydroxyl group. The oxygen on the aldehyde carbon gives hydrogenation to the hydroxyl group, and the aldehyde is then an alcohol, that is, 2-pyridyl ethanol. Although lithium aluminum hydride has strong strength, it is strong in nature, and it needs strict waterproofing and air. The operation is harsh, and it is difficult to do if you are not familiar with it.
Third, it is hydrolyzed with 2-pyridyl acetonitrile as a precursor. 2-pyridyl acetonitrile dances with water under the catalysis of acid or base. The nitrile group is hydrolyzed to form an amide first, and then an amide is hydrolyzed to form a carboxyl group. If the carboxyl group is reduced in an appropriate way, 2-pyridyl ethanol can also be obtained. This process of hydrolysis requires both the degree of acid and base and the time of reaction. If you are not careful, you will get twice the result with half the effort.

2 - Pyridyl ethanol is an organic compound. When storing, many things need to be paid attention to.
First, it is related to the temperature and humidity of the storage environment. This substance should be stored in a cool and ventilated place. If the temperature is too high, it may increase its volatilization and even cause safety risks; if the humidity is too high, it may cause it to be damp and affect the quality. Therefore, the storage temperature should usually be controlled between 15 ° C and 25 ° C, and the relative humidity should be maintained at 40% to 60%.
Second, about the effect of light. 2 - Pyridyl ethanol should be avoided from direct light because it is more sensitive to light, and light may cause it to undergo chemical reactions, resulting in deterioration. Therefore, the storage container should be made of dark glass or opaque plastic, and stored in a dark place.
Third, the choice of container is also the key. The selected storage container must ensure good sealing to prevent it from coming into contact with air. Due to exposure to air, 2-pyridyl ethanol is easily oxidized, thus changing its chemical properties. The container material should also be compatible with 2-pyridyl ethanol and should not react with it.
Fourth, fire and explosion protection should not be ignored. 2-pyridyl ethanol is flammable, and the storage place must be kept away from fire and heat sources, and fireworks are strictly prohibited. And it needs to be equipped with corresponding fire facilities and equipment to prevent accidents.
Fifth, classified storage is also the key. Do not mix 2-pyridyl ethanol with oxidants, acids, bases and other substances, because these substances come into contact with them, or cause violent chemical reactions, endangering safety.
In short, storing 2-pyridyl ethanol requires careful consideration from various aspects such as temperature and humidity, light, container, fire and explosion protection, and classified storage to ensure its quality and storage safety.

2-Pyridyl ethanol, the price on the market, often varies due to the purity of the product and the situation of supply and demand. The pure one, the price may be slightly higher; the inferior one, the price is cheap. And the amount of production and the demand for it are also the reasons for the price movement.
If you ask for its exact price, you should consult the merchants in the city. In the field of chemical materials, or the platform of e-commerce, you can get an approximate price. However, the price of various places may be different, or due to the distance of the place and the difficulty of transportation, the cost is different, and the price also changes accordingly.
In the past, the supply and demand of the city were flat, and the price was still stable. However, in recent years, the industry of chemical industry has flourished, and there are many people who seek it, and its price may have risen. And the cost of the process and materials is related to the price. If the material is expensive and complex, the price must be high; otherwise, the price may decline.
To know the real-time price, you can check the information of the chemical industry in detail, or negotiate with various suppliers to get a near-real market price.