As a leading 2-Pyridineethanol, 伪-(2,4-difluorophenyl)-尾,尾-difluoro-伪-(1H-tetrazol-1-ylmethyl)-5-[4-(2,2,2-trifluoroethoxy)phenyl]-, (伪R)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
2-Pyridineethanol, pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazol-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) - What is the chemical structure?
This compound is a complex organic compound with specific chirality, derived from the structure of pyridyl ethanol. The following is to explain its chemical structure in the classical Chinese style of "Tiangong Kaiwu":
Looking at this compound, it is based on 2-pyridyl ethanol, with one end attached to pseudo (2,4-difluorophenyl) and the other end connected to difluoro pseudo (1H-tetrazole-1-ylmethyl). Furthermore, it has [4- (2,2,2-trifluoroethoxy) phenyl] at the 5th position. And this compound has (R) -chirality, which is like a unique optical rotation property endowed by natural creation. Its overall structure is like an exquisitely constructed microscopic pavilion. The groups are connected like mortise and tenon to build this complex and unique chemical entity. Each part is interdependent and collaboratively determines its physical and chemical properties. In the field of organic chemistry, this structure is like a unique pearl, waiting for researchers to use the key of wisdom to explore its hidden mysteries and understand its many wonders in reaction, synthesis and application.
2-Pyridineethanol, pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazol-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) - What are the physical properties?
(The chemical name of this substance is verbose and complex, and the following is referred to as "this compound") This compound is an organic compound with a complex structure. Its physical properties are as follows:
- ** Appearance traits **: It is often white to light yellow crystalline powder, which is derived from the interaction force and arrangement of its molecules. Each atom in the molecule is connected by a specific chemical bond to form a specific spatial structure. When many molecules gather, it appears like this.
- ** Melting point **: about 135-138 ° C. When the temperature rises to this range, the thermal motion of the molecule intensifies enough to overcome the lattice energy, the lattice structure disintegrates, and the substance changes from a solid state to a liquid state. Interactions between different groups in the molecule, such as hydrogen bonds, van der Waals forces, etc., jointly determine the melting point. < Br > - ** Solubility **: Slightly soluble in water, but easily soluble in organic solvents such as ethanol and dichloromethane. Water is a polar solvent. Although this compound contains polar groups, the hydrophobic part of the overall structure accounts for a large proportion, and the interaction with water is weak. The organic solvent and the compound molecules can interact through similar intermolecular forces, such as hydrogen bonds or van der Waals forces in ethanol, so it is easily soluble.
- ** Density **: Under specific conditions, the density is about 1.25 g/cm ³. This is determined by its molecular mass and the degree of intermolecular accumulation, reflecting the distribution of molecules in unit volume. < Br > - ** Stability **: It has certain stability under normal conditions. However, because it contains multiple special groups, when encountering strong oxidizing agents, strong acids or strong bases, the chemical bonds in the structure may be attacked and react, and the stability is affected.
What is the use of 2-Pyridineethanol, pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazol-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) -?
This is a special heterogeneous organic compound named (R) -pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazole-1-ylmethyl) -5 - [4 - (2,2,2-trifluoroethoxy) phenyl] -2 -pyridyl ethanol. However, its use is hard to find in ancient books such as "Tiangong Kaiwu". Gai "Tiangong Kaiwu" was written by Ying Xing in the Ming Dynasty, detailing various production technologies in agriculture and handicrafts. At that time, the synthesis and application of such organic compounds were far from being developed.
This compound is mostly found in the field of contemporary organic chemistry and medicinal chemistry. Or used to create new drugs, with its special chemical structure, it precisely fits with the target in the body, intervenes in physiological and pathological processes, and treats diseases. It may also emerge in the field of materials science, giving materials unique chemical and physical properties, such as improving material stability, solubility or reactivity. However, the exact use needs to be referred to modern chemistry, medicine and related scientific literature to clarify the details.
2-Pyridineethanol, pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazol-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) - What are the synthesis methods?
Preparation of (R) -2-pyridyl ethanol, pseudo- (2,4-difluorophenyl) -terminal, terminal-difluoro-pseudo- (1H-tetrazole-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] - The synthesis method is as follows:
The starting material is selected from a compound containing pyridine structure and suitable substituents, and the target molecular structure is gradually built based on classical organic reactions.
In the first step, a nucleophilic substitution reaction can be used to react the pyridine-containing ethanol structural fragment with a (2,4-difluorophenyl) derivative with an appropriate leaving group to construct a pseudo- (2,4-difluorophenyl) moiety. The reaction conditions, such as temperature, solvent, and base type and dosage, need to be precisely controlled to ensure the smooth progress of the reaction and good regioselectivity.
The second step is to introduce a terminal-difluoro-pseudo- (1H-tetrazole-1-ylmethyl) structure, first introduce a group that can be converted into tetrazole at a suitable position through a specific reaction, such as a nitrile group, etc., and then form a tetrazole ring through a cyclization reaction, while introducing a difluoro substituent. This process should pay attention to the stability of the reaction intermediate and the stereochemical control of the reaction.
Finally, the 5- [4- (2,2,2-trifluoroethoxy) phenyl] part is introduced, and the 4-hydroxyphenyl derivative can be reacted with 2,2,2-trifluoroethylation reagent under the action of appropriate base and catalyst by means of etherification reaction to complete the connection of the fragment.
During the whole synthesis process, suitable separation and purification methods, such as column chromatography, recrystallization, etc. are used after each step of the reaction to obtain high-purity intermediates and final products. At the same time, the structure of the products is confirmed by spectroscopy techniques such as NMR and MS.
2-Pyridineethanol, pseudo- (2,4-difluorophenyl) -end, end-difluoro-pseudo- (1H-tetrazol-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) - What are the common specifications on the market?
2-Pyridyl ethanol, pseudo- (2,4-difluorophenyl) -end, end-difluoro-pseudo- (1H-tetrazole-1-ylmethyl) -5- [4- (2,2,2-trifluoroethoxy) phenyl] -, (R) - This product is commonly specified in the market, with the following numbers.
The specifications are often related to purity and packaging. The standard of purity, or the state of high purity, such as more than 98%, this high purity is mostly suitable for areas with strict purity requirements such as fine synthesis and pharmaceutical research and development, which can ensure the accuracy of the reaction and the purity of the product.
Packaging specifications are also diverse. Common products are in grams, such as small packages of 5 grams and 10 grams, which are convenient for scientific research institutions to use in small quantities for experimental exploration. In the initial research stage, they can be accurately weighed on demand and do not cause waves. There are also large packages in kilograms, such as 1 kg, 5 kg, etc., which are mostly used in industrial production. Sufficient supply can meet the needs of large-scale preparation. < Br >
And it may be formulated into a specific concentration solution according to different uses and customer needs. If it is used for a specific catalytic reaction, or a solution of a certain concentration, it will make the operation more convenient and the reaction easier to regulate. Such specifications are born in response to various needs in the city, suitable for different industries and different stages.
