2 Pyridinecarboxylicacid 5 6 Dichloro
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinecarboxylicacid, 5,6-dichloro-

    Specifications

    HS Code

    738088

    Name 5,6 - dichloro - 2 - pyridinecarboxylic acid
    Molecular Formula C6H3Cl2NO2
    Molecular Weight 192.00
    Appearance Solid (Typical)
    Physical State At Room Temp Solid
    Melting Point 198 - 200 °C
    Solubility In Water Poor solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Pka Around 2 - 3 (approximate, acidic nature due to carboxylic acid group)
    Chemical Class Heterocyclic carboxylic acid
    Odor Odorless (Typically)
    Color White to off - white

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    General Information
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    Frequently Asked Questions

    As a leading 2-Pyridinecarboxylicacid, 5,6-dichloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-pyridinecarboxylic acid, 5,6-dichloro-?
    2-Pentenoic acid, 5,6-dibromo - is mainly used in the field of organic synthesis. It has a wide range of uses and is unique, and plays a key role in many chemical synthesis reactions.
    In terms of fragrance preparation, 2-pentenoic acid, 5,6-dibromo can be converted into a substance that emits a unique aroma through a specific reaction process. Due to the presence of unsaturated bonds and bromine atoms in its structure, it can form complex compounds with special flavors through chemical reactions. It is often used in the preparation of high-end perfumes, air fresheners and food flavors, etc., to give products a unique aroma and improve product quality and attractiveness.
    In the chemical synthesis of medicine, this compound is also indispensable. Its structure can be used as a key intermediate to participate in the synthesis of many drug molecules. With the help of chemical reactions to modify and modify its structure, compounds with specific pharmacological activities can be synthesized, or as lead compounds, through further optimization and research, new drugs can be developed. For example, in the development of some antibacterial and anti-inflammatory drugs, 2-pentenoic acid, 5,6-dibromine play an irreplaceable role as starting materials or important intermediates.
    In the field of materials science, this compound also shows important value. Because of its special functional groups, it can participate in polymerization reactions to prepare polymer materials with special properties. For example, polymerization with specific monomers can endow materials with good thermal stability, mechanical properties or optical properties, and can be used to make high-performance plastics, fibers and coatings, etc., to meet the needs of different fields for special properties of materials.
    In short, 2-pentenoic acid, 5,6-dibromo, with its unique chemical structure, has important uses in the fields of flavors, medicine, materials, etc., promoting the development and innovation of these fields.
    What are the physical properties of 2-pyridinecarboxylic acid, 5,6-dichloro-
    The physical properties of 2-% pentenoic acid, 5,6-dibromo-are related to its appearance, melting point, solubility, density and other characteristics.
    First of all, its appearance, this compound may be liquid at room temperature, colorless or slightly light-colored, and the appearance is clear. Due to the presence of carbon-carbon double bonds and bromine atoms, the structure is slightly complex, but it does not contain too many conjugated systems, so it may not be dark.
    In terms of melting point, the intermolecular force caused by carbon-carbon double bonds changes, while the bromine atom has a large atomic weight and electron cloud, which enhances the intermolecular dispersion force. Therefore, compared with saturated carboxylic acids with the same number of carbon atoms, their boiling point may be higher, because more energy is required to overcome intermolecular forces to achieve gas-liquid conversion; the melting point is also affected by molecular regularity, due to the substitution of double bonds with bromine atoms, the molecular regularity is not good, and the melting point may not be too high.
    In terms of solubility, because it contains carboxyl groups, it has a certain polarity, and it may have a certain solubility in polar solvents such as water. However, with the growth of carbon chains and the introduction of bromine atoms, the hydrophobicity also increases, so its solubility in water may be limited. In common organic solvents such as ethanol and ether, due to the principle of similar miscibility, the solubility may be high, and it can be well miscible. In the case of
    density, the atomic weight of bromine atoms is very large, which significantly increases the molecular weight, and its space occupies a certain volume, resulting in the density of this compound being larger than that of ordinary hydrocarbons and simple carboxylic acids, or greater than that of water. If mixed with water, or sinking in the bottom.
    In short, 2-% pentenoic acid, 5,6-dibromo-due to its unique molecular structure, has such physical properties, which affect its application and treatment methods in the fields of chemical industry and organic synthesis.
    What are the chemical properties of 2-pyridinecarboxylic acid, 5,6-dichloro-
    The chemical properties of 2-% hydroxyglutaric acid and 5,6-dihydroxy group are as follows:
    2-hydroxyglutaric acid, which has two functional groups: carboxyl group and hydroxyl group. The carboxyl group makes it acidic and can be neutralized with bases, such as reacting with sodium hydroxide to form corresponding carboxylic salts and water. The hydroxyl group can participate in a variety of reactions, such as esterification reaction under appropriate conditions, and carboxylic acid can form esters under concentrated sulfuric acid catalysis and heating conditions. At the same time, the hydroxyl group also has a certain degree of reductivity and can be oxidized under the action of some oxidants, such as by weak oxidants to make new copper hydroxide suspensions, or by strong oxidants such as acidic potassium permanganate solution. If the carbon in which the hydroxyl group is located is connected to two hydrogen atoms, it can be gradually oxidized to aldehyde and carboxyl groups.
    5,6 -dihydroxy compounds, the presence of two hydroxyl groups increases the hydrophilicity of the molecule, making it more soluble in water. Hydroxyl groups can also undergo esterification reactions. If there are other suitable functional groups in the molecule, complex compound structures can be constructed by controlling the reaction conditions and using the reactivity of hydroxyl groups. Moreover, two adjacent hydroxyl groups make the electron cloud density in this area higher, and under the action of some electrophilic reagents, reactions may preferentially occur near the hydroxyl group. In addition, these two hydroxyl groups may affect the physical properties of the compound through intramolecular or intermolecular hydrogen bonds, such as melting point and boiling point. The presence of intermolecular hydrogen bonds generally increases the melting point and boiling point. In the oxidation reaction, hydroxyl groups can be oxidized, and adjacent hydroxyl groups may undergo special oxidation rearrangements and other reactions under the action of some special oxidants, resulting in products with different structures and exhibiting unique chemical properties.
    What is the preparation method of 2-pyridinecarboxylic acid, 5,6-dichloro-
    To prepare 2-hydroxyglutaric acid in a 5,6-dioxy environment, the method is as follows:
    First take a suitable starting material, such as those with a corresponding carbon chain structure and containing functional groups that can be converted into hydroxyl and carboxyl groups. It is possible to find something with a pentyl carbon chain and one end that is easily oxidized to a functional group, such as pentanol derivatives. Place it in a specific oxidation system, which needs to be carefully prepared to precisely oxidize to obtain the desired carboxyl and hydroxyl groups.
    If it is discussed in an ancient way, or first use a mild oxidizing agent, such as some metal oxides mixed with a specific acid solution, slowly oxidize the hydroxyl group at one end of the pentanol to gradually form a carboxyl group. However, this process requires close attention to the degree of reaction to prevent excessive oxidation from causing product hybridization. After the carboxyl group at one end is initially formed, try to introduce the hydroxyl group at the 2-position. Halogenation can be used to introduce halogen atoms at the 2-position of valeric acid, and suitable halogenating agents can be selected to control the reaction conditions so that the halogenation reaction can occur precisely at the target position.
    Then reacts with halogenated valeric acid with hydroxyl-containing reagents, such as alkoxides, etc., and the halogen atoms are replaced by hydroxyl groups to obtain 2-hydroxyvaleric acid. As for the creation of a 5,6-dioxy environment, a specific protective group can be used to treat the 5,6-position functional group with a suitable protective agent to form a stable protective structure and reach the state of dioxy. After the main structure of 2-hydroxyglutaric acid is synthesized, the protective group is carefully removed to obtain pure 2-hydroxyglutaric acid. The whole process needs to strictly control the reaction conditions of each step, such as temperature, pH, reaction time, etc., and it is difficult to obtain the ideal product if there is a slight difference.
    2-Pyridinecarboxylic acid, 5,6-dichloro - what is the price range on the market?
    The price range of 2-% pentenoic acid, 5,6-dibromo - in the market varies due to a variety of factors. This substance is widely used in the chemical industry, and its price is determined by many factors such as raw material cost, production process, market supply and demand relationship.
    Let's talk about the cost of raw materials first. The fluctuation of the price of raw materials related to pentenoic acid and bromine directly affects its production cost. If the supply of raw materials is tight, the price will rise, and the price of the product will also rise. The complexity of the production process is also very critical. If the production process requires high-end technology and precision equipment, the input cost is high, and the price is naturally not low. In terms of market supply and demand, if the demand for 2-% pentenoic acid, 5,6-dibromo-is strong, and the supply is limited, the price is easy to rise; on the contrary, if the market oversupply, the price will decline.
    Generally speaking, purity, packaging specifications, etc. also affect the price. High-purity products are more difficult to produce, and the price is higher than that of ordinary purity. Small packaging products have higher unit prices due to high packaging costs. In the current market environment, the price of 2-% pentenoic acid, 5,6-dibromo-is roughly in the range of [X] yuan to [X] yuan per kilogram. However, the market is constantly changing, and specific prices need to be consulted by relevant chemical product suppliers and distributors, or by referring to real-time quotations on chemical product trading platforms, in order to obtain accurate price information.