2 Pyridinecarboxylic Acid 5 Methyl
pyridine pyrrole pyrazine piperidine piperazine

2-pyridinecarboxylic acid, 5-methyl-

    Specifications

    HS Code

    142192

    Name 5 - methyl - 2 - pyridinecarboxylic acid
    Molecular Formula C7H7NO2
    Molecular Weight 137.14 g/mol
    Appearance Solid (usually white or off - white powder)
    Melting Point 187 - 190 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol
    Pka Value Around 4.8 (approximate value for the carboxylic acid group)
    Odor Odorless (usually)
    Crystal Structure May form monoclinic or orthorhombic crystals (reported in some studies)

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    Frequently Asked Questions

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    What are the chemical properties of 5-methyl-2-pyridinecarboxylic acid?
    5-Methyl-2-pentenoic acid is an organic compound. It has many unique chemical properties.
    First of all, it is acidic. 5-methyl-2-pentenoic acid contains a carboxyl group (-COOH), which gives it acidic properties. The hydrogen atoms in the carboxyl group can be partially ionized, releasing hydrogen ions (H 🥰) in the aqueous solution, making the solution acidic. If it encounters alkali substances such as sodium hydroxide (NaOH), a neutralization reaction will occur, resulting in the formation of corresponding carboxylates and water. This is a typical reaction of organic acids, whereby various carboxylates can be prepared, which are widely used in organic synthesis and industrial production.
    Furthermore, 5-methyl-2-pentenoic acid contains a carbon-carbon double bond (C = C), which makes the compound unsaturated and capable of addition reactions. For example, it can be added to hydrogen (H ²) under the action of a suitable catalyst, and the carbon-carbon double bond is broken. Hydrogen atoms are added to the double-bonded carbon atoms to form saturated 5-methylpentanoic acid. It can also be added to halogens (such as bromine Br ²). The bromine-bromine bond in the bromine molecule is broken, and two bromine atoms are added to the carbon atoms at both ends of the double bond to form a dibromo substitute. Such addition reactions can be used to introduce new functional groups in organic synthesis to prepare more complex organic compounds.
    In addition, 5-methyl-2-pentenoic acid can also undergo polymerization due to the presence of carbon-carbon double bonds. Under specific initiators and reaction conditions, the double bonds are opened, and many 5-methyl-2-pentenoic acid molecules are connected to each other to form a polymer. This polymer may have unique physical and chemical properties and may have potential application value in materials science and other fields.
    At the same time, different groups in the 5-methyl-2-pentenoic acid molecule interact with each other, resulting in rich and diverse chemical properties. It can undergo substitution reactions, and hydrogen atoms at ortho or other positions of the carboxyl group can be replaced by other atoms or groups under suitable reagents and conditions, resulting in the derivation of many derivatives with different structures and properties, providing rich choices for organic synthesis.
    What are the physical properties of 5-methyl-2-pyridinecarboxylic acids?
    5-Methyl-2-pentenoic acid is an organic compound, and its physical properties are quite unique. The details are as follows:
    1. ** Properties **: Under normal temperature and pressure, this substance is mostly colorless to light yellow liquid. It looks like a clear oil, with a shiny flow, and under specific light conditions, it will refract a soft light.
    2. ** Smell **: It has a unique and strong pungent smell, which is impressive to smell. This smell is slightly sour, but mixed with some indescribable special smell. When you smell it closely, you can clearly sense its pungent nature. When it spreads in the air, it is very easy to be detected by people.
    3. ** Boiling point **: Its boiling point is about 203-204 ° C. When it is heated and the temperature gradually rises to this range, 5-methyl-2-pentenoic acid will transform from liquid to gaseous state, and a violent vaporization phenomenon will occur, forming a curling rising steam.
    4. ** Melting point **: The melting point is about -22 ° C. When the external temperature drops to this value and below, the originally flowing liquid 5-methyl-2-pentenoic acid will gradually solidify and turn into a solid state, and the texture will also become hard.
    5. ** Solubility **: 5-methyl-2-pentenoic acid is slightly soluble in water. When mixed with water, only a small amount can interact with water molecules to disperse, and most of them will float on the water surface in the form of oil droplets, showing obvious stratification. However, it is easily soluble in organic solvents such as ethanol and ether. Once in contact with these organic solvents, they will quickly blend with each other to form a uniform and stable solution.
    6. ** Density **: The density is about 0.942g/cm ³. Compared with water, its density is slightly less than that of water, so when it is dropped into water, it will float on the water surface. This density property allows it to follow specific physical laws when mixing with other substances or performing separation operations.
    What are the main uses of 5-methyl-2-pyridinecarboxylic acid?
    5-Methyl-2-pentenoic acid, an organic compound, has important uses in many fields.
    In the field of fragrances, it emits a unique aroma and is often used as a fragrance ingredient to endow perfumes, cosmetics and various fragrance products with unique fragrance, create a different atmosphere, and enhance the olfactory experience of products.
    In the field of food additives, it can add special flavors to food. In the production of beverages, candies, baked goods, etc., the flavor of food is optimized and the taste enjoyment of consumers is enhanced. However, the amount used needs to be strictly controlled in accordance with relevant food regulations.
    In the field of pharmaceutical chemicals, it is an important organic synthesis intermediate. Through a series of chemical reactions, a variety of drugs can be synthesized, which is of great significance for the treatment of diseases; it also acts as a key raw material in the preparation of some chemical products, promoting the development of the chemical industry.
    In addition, in the agricultural field, some of its derivatives may have the functions of regulating plant growth or deworming, and help agricultural production.
    In short, 5-methyl-2-pentenoic acid plays a key role in many industries due to its own characteristics. With the development of science and technology and industry, its application prospects may be broader.
    What is the preparation method of 5-methyl-2-pyridinecarboxylic acid?
    The preparation of 5-methyl-2-pentenoic acid is related to the technology of chemical synthesis. The method has various paths, which are described in detail today.
    First, it can be obtained by oxidation of the corresponding alcohol or aldehyde. For example, using 5-methyl-2-pentenol as the starting material, choose a suitable oxidizing agent, such as Jones reagent, that is, the mixture of potassium dichromate ($K_2Cr_2O_7 $) and sulfuric acid ($H_2SO_4 $). Under appropriate reaction conditions, the alcohol hydroxyl group can be oxidized to a carboxyl group to obtain 5-methyl-2-pentenoic acid. In this process, it is necessary to pay attention to the control of the reaction temperature, the proportion of reactants and the reaction time. If the temperature is too high, it may cause excessive oxidation or double bond side reactions; if the ratio is improper, it may affect the yield; if the time is too short, the reaction will not be fully functional, and if it is too long, it may cause other side reactions.
    Second, it is prepared by the substitution and carboxylation of halogenated hydrocarbons. First, use a suitable halogenating agent to halogenate 5-methyl-2-pentene to generate halogenated 5-methyl-2-pentene. Subsequently, it reacts with metal magnesium to form Grignard reagent, and then reacts with carbon dioxide to obtain 5-methyl-2-pentenoic acid after hydrolysis. This path requires attention to the selectivity of the halogenation reaction to ensure that the halogen atom is substituted in a suitable position; when preparing Grignard reagent, the reaction system needs to be anhydrous and oxygen-free, otherwise Grignard reagent is easy to decompose.
    Third, through the carbonylation of olefins. Using 5-methyl-2-pentene as raw material, in the presence of carbon monoxide ($CO $) and a suitable catalyst, and reacting with hydrogen ($H_2 $) or water ($H_2O $), olefin can be converted into carboxylic acid. This method requires high-efficiency catalysts, such as some transition metal complexes, and the reaction conditions are relatively harsh. It is necessary to control the pressure of carbon monoxide, reaction temperature and other factors in order to achieve good yield and selectivity.
    There are various methods for preparing 5-methyl-2-pentenoic acid, each with its own advantages and disadvantages. In practical application, the best method needs to be weighed according to specific needs and conditions.
    What are the precautions for storing and transporting 5-methyl-2-pyridinecarboxylic acids?
    5-Methyl-2-pentenoic acid requires careful attention during storage and transportation.
    It is active and requires strict storage environment. This acid is volatile to a certain extent. If the storage container is not well sealed, it is easy to cause volatile loss and reduce the concentration of components. And it should be placed in a cool, dry and well-ventilated place, away from heat sources and open flames. Because of its heat or exposure to open flames, there is a risk of combustion or even explosion.
    Furthermore, 5-methyl-2-pentenoic acid has a corrosive effect on metals. Metal materials should not be used for storage containers. Corrosion-resistant plastics, glass and other materials should be used. Corrosion of metals not only damages the container, but also may mix the acid with impurities, which affects the quality.
    When transporting, the packaging must be solid and reliable. Make sure that the container is sealed and wrapped with buffer material to prevent the container from being damaged due to collision and vibration during transportation and acid leakage.
    In addition, 5-methyl-2-pentenoic acid has an irritating odor and certain toxicity. Transportation and storage personnel should take protective measures, wear gas masks, gloves, and protective clothing. In the event of acid leakage, personnel should quickly evacuate to a safe area and take corresponding emergency measures according to the leakage situation. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; a large amount of leakage needs to be built embankment or excavated for containment, transferred to a tank car or a special collector by pump, recycled or transported to a waste treatment site for disposal.
    During transportation, follow relevant regulations and standards, and do not mix with oxidants, alkalis, etc., to prevent chemical reactions. Strictly control the transportation temperature and humidity to ensure transportation safety. In this way, the safety and quality of 5-methyl-2-valenoic acid during storage and transportation can be guaranteed.