2 Pyridinecarboxylic Acid 5 Iodo
pyridine pyrrole pyrazine piperidine piperazine

2-pyridinecarboxylic acid, 5-iodo-

    Specifications

    HS Code

    251554

    Chemical Formula C6H4INO2
    Molar Mass 249.006 g/mol
    Appearance Solid (predicted)
    Boiling Point 350.9°C at 760 mmHg (predicted)
    Melting Point 193 - 197 °C
    Density 2.087 g/cm³ (predicted)
    Pka 2.49 (predicted)
    Solubility In Water Slightly soluble (predicted)
    Flash Point 166.0°C (predicted)
    Logp 1.69 (predicted)

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    Frequently Asked Questions

    As a leading 2-pyridinecarboxylic acid, 5-iodo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    2-pyridinecarboxylic acid, what is the chemical property of 5-iodo-
    5-Iodine-2-pyridinecarboxylic acid, this is an organic compound with unique chemical properties. Its appearance is often a crystalline solid, relatively stable at room temperature and pressure.
    From the structural point of view, the pyridine ring is connected to carboxyl and iodine atoms. The pyridine ring endows it with certain aromaticity, which gives the molecule a specific electron cloud distribution and stability. The presence of carboxyl (-COOH) makes the compound acidic, and hydrogen ions can be dissociated under appropriate conditions. It can neutralize and react with bases to form corresponding salts.
    The iodine atom is a halogen atom with high electronegativity, which introduces molecular polarity changes and affects the physical and chemical properties of the compound. Iodine atoms can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Under appropriate reagents and conditions, iodine atoms can be replaced by other groups to construct new compound structures, which are widely used in the field of organic synthesis.
    Furthermore, the solubility of 5-iodine-2-picolinecarboxylic acid is related to the molecular structure. Its solubility in polar solvents (such as water and alcohols) is better than that of non-polar solvents. This property needs to be considered in the separation, purification and construction of reaction systems. In chemical reactions, due to its structural characteristics, it can be used as an important intermediate to participate in the synthesis of various compounds such as drugs and materials, showing unique chemical activity and application value.
    2-pyridinecarboxylic acid, what are the main uses of 5-iodo-
    5-Iodine-2-pyridinecarboxylic acid, an organic compound. It has a wide range of uses and is often used as an intermediate in drug synthesis in the field of medicine. The unique structure of the pyridine ring and the iodine atom gives it a specific chemical activity and spatial configuration, which can introduce key structural fragments to drug molecules to optimize the activity, selectivity and pharmacokinetic properties of drugs. For example, when developing some antibacterial and antiviral drugs, its structural properties can be used to construct molecular structures that are in line with the target of pathogens and enhance the efficacy of drugs.
    In the field of materials science, 5-iodine-2-pyridinecarboxylic acid also has its uses. It can participate in the preparation of functional materials, such as organic materials with specific optical and electrical properties. Its iodine atom and pyridine ring structure can affect the electron cloud distribution and conjugation system of the material, thereby regulating the luminous properties and conductivity of the material. When preparing organic Light Emitting Diode (OLED) materials, its structural properties can be used to optimize the luminous efficiency and stability of the material.
    In the field of chemical research, it is often used as a reagent for organic synthesis. With its acidity and the reactivity of pyridine ring and iodine atom, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, metal-catalyzed coupling reactions, etc. With this, chemists can construct more complex organic molecular structures, expand the methods and routes of organic synthesis, and provide effective means for the creation of new compounds.
    In short, although 5-iodine-2-picolinecarboxylic acid is an organic compound, it has important uses in many fields such as medicine, materials science, and chemical research, and is of great significance to promote the development of related fields.
    What are the synthesis methods of 2-pyridinecarboxylic acid, 5-iodo-
    The synthesis of 5-iodine-2-pyridinecarboxylic acid is a very important topic in the field of organic synthesis. There are many ways to synthesize it, which are described in detail below.
    First, pyridine can be started from pyridine. First, pyridine is introduced into iodine atoms through a halogenation reaction under specific conditions to obtain iodine-substituted pyridine. This halogenation reaction requires careful selection of halogenating reagents, such as iodine elementals in combination with appropriate oxidizing agents, or specific iodine-containing reagents, and the reaction temperature, time and solvent must be strictly controlled to promote the precise substitution of iodine atoms at the fifth position of the pyridine ring. Subsequently, iodopyridine is carboxylated. This carboxylation step can be used, such as the interaction of carbon dioxide with metal-organic reagents (such as Grignard reagents), that is, in an anhydrous and oxygen-free environment, the Grignard reagent of iodine-substituted pyridine is first prepared, and then it is reacted with carbon dioxide, and then acidified to obtain 5-iodine-2-pyridinecarboxylic acid.
    Second, 2-pyridinecarboxylic acid can also be used as the starting material. The carboxyl group of 2-pyridinecarboxylic acid should be properly protected to prevent it from being affected in subsequent reactions. There are many ways to protect the carboxyl group, such as forming an ester group. Then the pyridine ring is halogenated, and the 5-position iodine substitution is achieved by reasonably selecting the halogenated reagents and optimizing the reaction conditions. Finally, the protected carboxyl group is deprotected to restore the structure of the carboxyl group, so as to obtain the target product 5-iodine-2-pyridinecarboxylic acid. The deprotection step needs to select the appropriate reaction conditions and reagents according to the type of protecting group used.
    Third, some more complex synthesis strategies can be used, such as the rearrangement reaction of pyridine derivatives. However, such methods usually require more stringent reaction conditions and require rich experience and skills in organic synthesis to be effectively implemented.
    In conclusion, the methods for synthesizing 5-iodine-2-pyridinecarboxylic acid are diverse and need to be carefully selected according to the actual raw material availability, reaction cost, yield and purity requirements and many other factors.
    2-pyridinecarboxylic acid, 5-iodo- in which areas is it widely used
    5-Iodine-2-pyridinecarboxylic acid is widely used in many fields such as medicine and chemical industry.
    In the field of medicine, it is often used as a key intermediate to synthesize many drugs. For example, some compounds with specific biological activities can be constructed by chemical reactions involving 5-iodine-2-pyridinecarboxylic acid. Due to its unique chemical structure, it can endow the synthesized drugs with special pharmacological properties, such as targeting specific cell receptors and regulating specific enzyme activities, which lays the foundation for the development of innovative drugs for the treatment of various diseases, and has potential value in the development of anti-tumor, anti-infection, and neurological diseases.
    In the chemical industry, 5-iodine-2-pyridinecarboxylic acid can be used as a catalyst ligand. It can coordinate with metal ions to form a specific structure of complexes, which play an important role in catalytic reactions. Like some organic synthesis reactions, it can improve the reaction rate and selectivity, make chemical production more efficient and accurate, and help synthesize high value-added organic compounds, which is of great significance to the development of the fine chemical industry. In addition, in materials science, it may participate in the preparation of materials with special properties. By reacting or modifying with other substances, it endows materials with unique electrical, optical or mechanical properties, expanding the scope of material applications.
    What is the market outlook for 2-pyridinecarboxylic acid, 5-iodo-
    5-Iodine-2-pyridinecarboxylic acid, the future of this product in the world, is related to many aspects, let me come one by one.
    Its use in the field of medicine may have unique potential. In today's world, medicine is developing rapidly, and the exploration of new compounds has never stopped. 5-Iodine-2-pyridinecarboxylic acid may be used as a key intermediate for the synthesis of specific drugs. With the current trend of pharmaceutical research and development, there is a growing demand for compounds with specific structures and activities. If they can demonstrate excellent pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc., they will surely win a place in the pharmaceutical market.
    In the field of materials science, there is also something to be traced. Today's material research pursues high performance and multi-functionality. If 5-iodine-2-pyridinecarboxylic acid can participate in material synthesis and endow materials with unique optical and electrical properties, it is expected to be applied to cutting-edge fields such as optoelectronic materials and sensors. The development of these emerging fields is like a prairie fire, and there is endless demand for new materials, so it may have broad prospects in this field.
    However, its market prospects are also constrained by many factors. The difficulty of the synthesis process is one of the keys. If the preparation process is complicated and the cost is high, even if the performance is excellent, it is difficult to promote on a large scale. And the market competition is fierce, with similar or alternative products emerging in an endless stream. If you want to stand out, you need to have unique advantages in performance and cost.
    Furthermore, the impact of regulations and policies cannot be underestimated. Regulations related to medicine and materials are becoming increasingly stringent, and 5-iodine-2-picolinecarboxylic acid needs to meet various safety and environmental protection standards in order to enter the market smoothly.
    Overall, although 5-iodine-2-picolinecarboxylic acid has potential value and broad prospects, it is still necessary to overcome many difficulties such as synthesis process, competitive pressure, and regulatory compliance in order to show its strength in the market. Only by forging ahead and continuously optimizing and improving can we seize opportunities and win the future.