2-Pyridinecarboxylic acid, 5-chloro-

5-Alkane-2-nonyl acid is an organic compound with interesting chemical properties.
This acid is acidic because of the carboxyl group. In aqueous solutions, the carboxyl group can be partially ionized, releasing hydrogen ions, making the solution acidic. Its acidity is weaker than that of inorganic strong acids, but it can neutralize with bases. If it meets sodium hydroxide, sodium 5-alkane-2-nonyl acid and water are formed. This reaction follows the general formula for acid-base neutralization: acid + base → salt + water. < Br >
5-alkane-2-nonyl acid contains long-chain alkyl groups, resulting in its limited solubility in water and certain lipophilic properties. This makes it soluble in many organic solvents, such as ethanol, ether, etc. With this property, it can be used as a solvent or intermediate in organic synthesis.
Because of its carboxyl group, it can participate in the esterification reaction. When with alcohols under suitable catalysts and conditions, ester compounds are formed. This reaction is often used to prepare fine chemicals such as fragrances and plasticizers. For example, when reacted with methanol, the corresponding methyl ester can be obtained. This process requires acid as a catalyst and heating to promote the reaction.
In addition, substitution reactions can occur on the alkyl chain of 5-alkane-2-nonyl acids. Under specific conditions, halogens and other substituents can replace hydrogen atoms on alkyl groups, thereby deriving a series of new compounds, opening up more paths for organic synthesis.
The chemical properties of 5-alkane-2-nonyl acids are rich and diverse, and have potential application value in organic synthesis, chemical industry and other fields. By understanding and controlling their properties, more novel compounds can be created and applied.

5-Alkane-2-nonyl acid, also known as an alkane-acid, this is an organic compound. Its physical properties are quite impressive, let me tell you one by one.
Looking at its properties, under room temperature, it is mostly liquid or solid. If the number of carbon atoms is small, the intermolecular force is relatively weak, often in a liquid state, with a lighter texture and good fluidity; when the number of carbon atoms increases, the intermolecular force increases, and it tends to be solid, and the texture is relatively solid.
When it comes to the melting boiling point, the melting boiling point increases with the increase in the number of carbon atoms. As the number of carbon atoms increases, the molecular mass increases, and the van der Waals force in the intermolecular force also increases. In order to make the molecules break free from each other and change from solid to liquid, or from liquid to gas, the energy required increases, so the melting boiling point increases. And the melting boiling point of the linear structure is slightly higher than that of the branched chain structure, because the linear chain molecule arrangement is more regular, the intermolecular contact area is large, and the action force is strong.
In terms of solubility, 5-alkane-2-nonyl acids are insoluble in water. Although it contains carboxyl groups (-COOH) in its molecules, this group has a certain polarity and can form hydrogen bonds with water molecules. However, the alkane group is non-polar. As the number of carbon atoms increases, the proportion of non-polar parts increases, which dominates the solubility of the molecule and makes it generally exhibit hydrophobic characteristics. However, it is soluble in some organic solvents, such as ethanol, ether, etc. Organic solvent molecules such as ethanol and ether can interact with 5-alkane-2-nonyl acid molecules through van der Waals forces, so they are mutually soluble.
As for the density, generally speaking, it is less than the density of water. This is because the proportion of carbon and hydrogen atoms in 5-alkane-2-nonyl acid molecules is relatively large, the atomic weight is relatively small, and the arrangement between molecules is not closely ordered, so that its unit volume mass is less than that of water.

The common preparation methods of 5-alkane-2-pentenoic acid are as follows:
First, pentene is used as the starting material. The pentene is first hydroformylated with carbon monoxide and hydrogen under the catalysis of a specific catalyst such as cobalt or rhodium under suitable temperature and pressure conditions to form aldehyde intermediates. This aldehyde intermediate is then oxidized by an oxidation process, such as oxygen or air. Under the action of suitable oxidants and catalysts, the aldehyde group is oxidized to a carboxyl group to obtain 5-alkane-2-pentenoic acid.
Second, starting from the corresponding halogenated hydrocarbon. A suitable halopentene is selected and reacted with sodium cyanide or potassium cyanide in an alcohol solvent to form a cyanyl substitute. Then the cyanyl group undergoes hydrolysis under acidic or basic conditions, and the cyanyl group is converted to a carboxyl group, and then the target product is obtained 5-alkane-2-pentenoic acid.
Third, through the synthesis of malonate esters. Diethyl malonate and halogenated alkanes under the action of alkaline reagents such as sodium alcohol undergo nucleophilic substitution and alkyl groups are introduced. After that, it reacts with suitable unsaturated halogenated hydrocarbons to construct a carbon chain structure. Finally, hydrolysis under basic conditions, followed by acidification and decarboxylation, can obtain 5-alkane-2-pentenoic acid.
The above methods have their own advantages and disadvantages. In actual preparation, it is necessary to comprehensively consider factors such as the availability of raw materials, the difficulty of reaction conditions, the cost and yield, and select an appropriate preparation route.

To prepare 5-bromo-2-pentenoic acid, you can do it as follows.
First take an appropriate amount of 2-pentene and place it in a clean reaction vessel. Slowly add a solution containing a brominating agent to it. The brominating agent can be a solution composed of liquid bromine and an appropriate solvent, such as carbon tetrachloride solution. During the dropwise addition process, close attention should be paid to the reaction temperature. The temperature can be controlled by water bath or other means to maintain the reaction temperature within a suitable range, generally 0-10 ° C. This reaction is an electrophilic addition reaction. Under the reaction conditions, the bromine molecule is heterolyzed into positive bromide ion and negative bromide ion. The positive bromide ion attacks the double bond of 2-pentene to form a bromide ion intermediate, and then the negative bromide ion attacks the bromide ion from the reverse side to generate 1,2-dibromopentane.
After obtaining 1,2-dibromopentane, place it in another reaction vessel with an appropriate amount of basic substance. The basic substance can be selected as an alcohol solution of potassium hydroxide. This reaction is carried out under heating conditions and is an elimination reaction. Hydroxide ions in the alcohol solution capture hydrogen atoms from the carbon atoms attached to the bromine atoms in 1,2-dibromopentane, while the bromine ions leave to form 2-bromo-2-pentene.
Subsequently, 2-bromo-2-pentene is co-placed in an autoclave with carbon monoxide, water, and a suitable catalyst. This catalyst can be selected from complexes containing transition metals such as palladium. Under a certain pressure and temperature, carbon monoxide and 2-bromo-2-pentene undergo carbonylation reaction, carbon monoxide is inserted between carbon-bromine bonds, and then water molecules attack, and under the action of catalysts, 5-bromo-2-pentenoic acid is finally formed.
The whole process requires fine operation and strict control of the reaction conditions to improve the yield and purity of the target product.

I look at what you are asking, but I am inquiring about the price range of 5-hydroxy- 2-indoleacetic acid in the market. However, the change of the price of this chemical product is often caused by many factors.
First, it is difficult to make. If the method of making this 5-hydroxy- 2-indoleacetic acid is difficult, the materials used are rare, and the manpower and material resources required are large, the price will be high. On the contrary, if the method is simple and the materials are easy to obtain, the price may be slightly flat.
Second, the situation of demand and supply. There are many people in the market who want this 5-hydroxy- 2-indoleacetic acid, but there are few suppliers, so the price will be higher. If the supply exceeds the demand, the merchant will reduce the price to compete for the market in order to sell its goods.
Third, the quality is good or bad. The best quality is 5-hydroxy- 2-indoleacetic acid, with few impurities, high purity, and the price is high if the quality is inferior.
Generally speaking, in today's city, the price of 5-hydroxy- 2-indoleacetic acid may be between tens of yuan and hundreds of yuan per gram. However, this is only an approximate number and is not a definite value. If you want to know the exact price, you should consult the merchant of chemical raw materials or check it carefully on the chemical product trading platform to obtain the actual price at that time.