2 Pyridinecarboxylic Acid 4 Iodo
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinecarboxylic acid, 4-iodo-

    Specifications

    HS Code

    553891

    Chemical Formula C6H4INO2
    Molar Mass 249.005 g/mol
    Appearance Solid
    Melting Point Data may vary, needs specific experiment
    Boiling Point Data may vary, needs specific experiment
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Density Data may vary, needs specific experiment
    Pka Value Data may vary, needs specific experiment
    Odor Odorless (usually)

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    Frequently Asked Questions

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    2-Pyridinecarboxylic acid, what is the chemical property of 4-iodo-
    4-Iodine-2-pyridinecarboxylic acid, this is an organic compound. Its nature is acidic, because it contains carboxyl groups, which can ionize hydrogen ions, so it has the characteristics of acid.
    Its physical rationality, at room temperature or as a solid, the specific properties vary depending on the purity and other factors. In terms of melting boiling point, due to the existence of various forces between molecules, such as hydrogen bonds, van der Waals forces, etc., the melting boiling point has a specific value, but the exact value needs to be accurately determined by experiments.
    In terms of solubility, according to the principle of similar miscibility, there may be a certain solubility in polar solvents. Because the carboxyl group is a polar group, it can interact with polar solvent molecules, but the solubility in non-polar solvents may be low.
    Chemical activity is quite high. Carboxyl groups can participate in many reactions, such as esterification with alcohols, and under acid catalysis, the corresponding esters and water are generated. It can also neutralize with bases to form carboxylic salts and water.
    The presence of iodine atoms gives the compound some properties of halogenated hydrocarbons. Iodine atoms can be replaced by nucleophiles, undergo nucleophilic substitution reactions, introduce other functional groups, and then synthesize compounds with more complex structures, which are widely used in the field of organic synthesis. And the compound may exhibit unique electronic and spatial effects due to the interaction between pyridine rings, carboxyl groups and iodine atoms, affecting its reactivity and selectivity.
    2-Pyridinecarboxylic acid, what are the physical properties of 4-iodo-
    4-Iodine-2-pyridinecarboxylic acid is an organic compound. Its physical properties are quite unique, let me explain in detail.
    Looking at its properties, at room temperature, it often appears in a solid state, mostly crystalline, with a white or white-like color. This is a common state, but also slightly different due to differences in preparation and purity.
    When it comes to the melting point, after many experiments, it is found that it is about a specific temperature range. This temperature is the critical point for its conversion from solid to liquid, and it is of great significance for its identification and purity judgment.
    Solubility is also an important property. In water, it is slightly soluble, and the polarity of water interacts with the structure of the compound, resulting in limited dissolution. However, in organic solvents, such as some polar organic solvents, the solubility is quite good. Due to the principle of similar miscibility, those with similar polarities are easy to dissolve with each other.
    In addition, its stability is also worthy of attention. Under general environmental conditions, it is relatively stable. In case of high temperature, strong light or specific chemical reagents, chemical reactions may also occur, resulting in changes in structure and properties.
    The physical properties of this compound are of great significance in many fields such as organic synthesis and drug development. Because of its specific properties, it can be used to design and synthesize new compounds, or as pharmaceutical intermediates, which can help the development of medicine.
    2-Pyridinecarboxylic acid, what is the main use of 4-iodo-
    4-Iodine-2-pyridinecarboxylic acid, an organic compound. It has a wide range of uses and has shown important value in many fields.
    In the field of medicinal chemistry, this compound is a key intermediate. Medical researchers can use it to synthesize drug molecules with specific biological activities. Due to the unique chemical properties of the pyridine ring and carboxyl and iodine atoms, it can interact with specific targets in organisms. For example, it can participate in the construction of inhibitors for certain disease-related proteins or receptors, providing key starting materials for the development of new drugs, and helping to create drugs with better efficacy and fewer side effects.
    In the field of materials science, 4-iodine-2-pyridinecarboxylic acid also has outstanding performance. It can act as a ligand and combine with metal ions to prepare metal-organic complex materials with special optical, electrical or magnetic properties. Such materials have potential applications in the fields of Light Emitting Diodes, sensors, and catalysis. For example, the formed complexes may have unique luminescent properties, which can be applied to the field of luminescent materials, contributing to the development of new and efficient luminescent materials.
    In the field of organic synthetic chemistry, it is an important synthetic building block. With the reactivity of iodine atoms and the modifiability of carboxyl groups, it can construct complex organic molecules through various organic reactions, such as coupling reactions and esterification reactions. Organic chemists can use it to expand the structural diversity of molecules, provide an effective way to synthesize organic compounds with specific functions, and promote the development of organic synthetic chemistry.
    What are the synthesis methods of 2-Pyridinecarboxylic acid, 4-iodo-
    There are many ways to synthesize 2-pyridinecarboxylic acid and 4-iodine. The synthesis of ancient times often depends on its chemical properties and reaction mechanism.
    First, pyridine can be used as the starting material. Introduce halogen atoms before the 4 position of pyridine, such as a suitable halogenating agent, through halogenation reaction to obtain 4-halogenated pyridine. Then make this halogenated pyridine react with reagents containing carboxyl groups under specific conditions. If carbon dioxide is used at high temperature and pressure and there is a catalyst, a carboxyl group can be introduced to obtain 2-pyridinecarboxylic acid, 4-halogenated-product. After the iodide, in a suitable reaction system, through the substitution reaction, the halogen atom is replaced by the iodine atom, that is, 2-pyridinecarboxylic acid, 4-iodine -.
    Second, other compounds with pyridine rings can also be started. If there are transformable groups on the ring, such as some substituents through oxidation, reduction, substitution and other series of reactions, the carboxyl group is gradually introduced at the 2nd position of the pyridine ring, and the iodine atom is introduced at the 4th position. For example, a pyridine derivative has a group that can be replaced by iodine at the 4th position. First, the carboxyl group is constructed at the 2nd position by a suitable oxidation method, and then the iodine substitution reaction is carried out to obtain the target product.
    Furthermore, the method of metal organic chemistry A coupling reaction catalyzed by metal catalysts, such as palladium and copper. First, a compound containing a pyridine ring with a couplable group at one end is prepared, and a reagent containing iodine and carboxyl groups is prepared. Under the action of a metal catalyst, 2-pyridinecarboxylic acid, 4-iodine - are synthesized in one or more steps through a coupling reaction. This method has advantages and disadvantages, and it is necessary to choose the appropriate one according to the actual conditions, such as the availability of raw materials, the difficulty of reaction, and the high or low yield.
    2-Pyridinecarboxylic acid, 4-iodo- what are the precautions in storage and transportation
    2-Pyridinecarboxylic acid, 4-iodine-This compound requires many precautions during storage and transportation. Its chemical properties are lively, and it must be stored in a cool, dry and well-ventilated place. Due to its hygroscopicity, contact with air or moisture may cause changes in its properties, so the packaging should be tight to prevent water vapor in the air from invading.
    Furthermore, this compound is more sensitive to heat, and it is easy to decompose or cause chemical reactions when heated. Storage temperature should be maintained at a low level, away from heat and fire sources. When transporting, avoid high temperature environment and violent vibration.
    At the same time, 4-iodine-2-pyridinecarboxylic acid may be toxic and corrosive, and protective measures must be taken during storage and transportation. Operators should be equipped with appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent contact and damage. And storage areas and transportation tools should be kept away from food, drugs and other items to prevent contamination.
    In addition, the storage and transportation process should strictly follow relevant regulations and standards, and make records and labels. Detailed labeling of compound names, properties, hazards and other information, so that in an emergency, appropriate response measures can be taken quickly to ensure the safety of personnel and the environment is not contaminated.