2 Pyridinecarboxylic Acid 4 Bromo 6 Chloro
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinecarboxylic acid, 4-bromo-6-chloro-

    Specifications

    HS Code

    866722

    Name 4-bromo-6-chloro-2-pyridinecarboxylic acid
    Chemical Formula C6H3BrClNO2
    Molar Mass 236.45 g/mol
    Appearance Solid (usually white or off - white powder)
    Solubility In Water Low (organic acid with halogen substituents, relatively hydrophobic)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF

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    Frequently Asked Questions

    As a leading 2-Pyridinecarboxylic acid, 4-bromo-6-chloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-bromo-6-chloro-2-pyridinecarboxylic acids?
    4-6-bromo-2-carboxylic acid, this is a compound with many characteristics. Its chemical properties are rich and rich, and it is worth exploring in depth.
    First, acidity is one of its important properties. Because the molecule contains a carboxyl group, it can exhibit typical acidity. It can neutralize and react to compounds. If it is oxidized, it will form carboxylic acid water. The normal mode of acid neutralization is useful in the fields of synthesis and chemical analysis.
    Second, the alkyl group also gives it many properties. The alkyl group has a certain water content, which makes the alkyl compound exhibit a specific solubility in some solvents. In addition, the alkyl group can be used for esterification reaction. If it encounters an alcoholic compound, an ester compound can be formed under the appropriate catalytic reaction. This reaction is important in the synthesis of flavors and compounds.
    Third, the presence of bromine atoms is also important. Bromine atoms have high activity and can generate substituted reactions. For example, under certain conditions, bromine atoms can be replaced by other functionalities such as amino groups and cyanos, etc., providing the possibility to synthesize more complex compounds. This property can be used in the synthesis of important groups.
    Fourth, the interaction of the empty functionalities of the compounds also affects their chemical activity. The sub-effects and immediate effects of each functional, etc., make the anti-activity of the compounds appear. The study of this interaction is of great significance for the precise control of chemical reactions and the synthesis of chemical compounds. In addition, the chemistry of 4-6-bromo-2 to its carboxylic acid is rich and subtle, and has great potential for application in both chemical research and related fields.
    What is the main use of 4-bromo-6-chloro-2-pyridinecarboxylic acid?
    4-6-aldehyde-2-pentenoic acid, its main use is described in "Tiangong", or has the following ends.
    This compound was used in ancient times, or it can be used in the way of use. In ancient times, the family often explored the properties of plants, trees, gold, and stones, in order to cure diseases and save people. 4-6-aldehyde-2-pentenoic acid or has some special principles, can be used to treat people and treat general diseases. For example, it can be used to treat some diseases, because of its characteristics of transformation, it can help people's blood and help the five organs recover.
    Furthermore, it can be used for dyeing. In ancient dyes, to obtain a long-lasting color, various natural or synthetic aids are often required. 4-6-aldehyde-2-pentenoic acid or because of its special activity, can be used as a media dye or a color aid. The dye is immersed in a dye solution containing this compound, which can make the dye better adhere to the material, the dyed color is firmer, and it is not easy to fade. And improve the quality of the product, so that the color of the product can be used for a long time or washed.
    may also be useful in some products. In ancient pottery, lacquer ware, etc., to make the surface of the object show a special feeling or color effect, use various additions. 4-6-aldehyde-2-pentenoic acid may be able to change the surface of the utensil to make it more glossy, or increase the beauty of the product.
    What are the synthesis methods of 4-bromo-6-chloro-2-pyridinecarboxylic acid?
    The synthesis method of 4-bromo-6-chloro-2-methoxybenzoic acid can be obtained from the following ways.
    First, the corresponding phenols are used as starting materials. First, the phenol and the halogenated hydrocarbon are reacted in an alkaline environment to achieve methoxylation. For example, phenol and bromomethane react with potassium carbonate and other bases in a suitable organic solvent, such as N, N-dimethylformamide (DMF), in a certain temperature to obtain methoxylation products. Subsequently, by halogenation reaction, bromine and chlorine atoms are introduced at specific positions in the aromatic ring. For example, in the presence of a suitable catalyst, such as iron powder or iron trihalide, it reacts with bromine, chlorine elemental substance or its corresponding halogenation reagent in an appropriate solvent, regulates the reaction conditions, and achieves precise halogenation at the desired position. Finally, through carboxylation reaction, a specific group is converted into a carboxyl group. For example, carbon dioxide is used as the carboxyl source, and under the action of a metal catalyst, carboxylation is realized to obtain the target product 4-bromo-6-chloro-2-methoxybenzoic acid.
    Second, halogenated aromatics are used as the starting material. Methoxy groups are introduced first, and nucleophilic substitution reactions can be used to react with halogenated aromatics with methoxylation reagents such as sodium methoxide, and react with methoxylation reagents such as sodium methoxide After that, the carboxylation reaction can be carried out, and the Grignard reagent method can be borrowed. Halogenated aromatics are first made into Grignard reagents, such as reacting with magnesium chips in anhydrous ether or tetrahydrofuran to make Grignard reagents, and then reacting with carbon dioxide, followed by acidification treatment to obtain carboxyl-containing products. Finally, under suitable conditions, another halogen atom is introduced at a specific position on the aromatic ring, and through a series of reactions, 4-bromo-6-chloro-2-methoxybenzoic acid is synthesized.
    Third, benzoic acid derivatives can be considered as starting materials. First, bromine and chlorine atoms are introduced in sequence on the aromatic ring of benzoic acid, and halogenation reactions are used to control the conditions to replace the halogen atoms at the designated positions. After that, the target product 4-bromo-6-chloro-2-methoxybenzoic acid is synthesized by methoxylation reaction, methoxy group is added, such as nucleophilic substitution mechanism, and suitable methoxylation reagent. All methods need to consider the reaction conditions, reagent selection and product separation and purification to achieve a good synthesis effect.
    What is the price range of 4-bromo-6-chloro-2-pyridinecarboxylic acid in the market?
    The price of 4-6-alkane-2-carboxylic acid in the market is determined by the price. The price of this compound is often affected by general factors.
    First, the cost of raw materials. If the raw materials are rare and available, or the cost of collection and extraction is high, the price of carboxylic acid will rise. Second, the synthesis is easy. If the synthesis method is complicated, multiple processes are required, and the rate of reaction of each step is not high, or special equipment is required, which will increase the cost and make the market go up. Third, the supply and demand of the market. If the market has a strong demand for this carboxylic acid, but the supply is limited, the price of natural water will be high; conversely, if the supply is limited, the price will drop.
    However, roughly speaking, if this is the case and the synthesis is easy, the price per gram may be between ten and one or two hundred words. If the synthesis is hard, or the raw materials are rare, the price per gram or more than 100 words, even as high as a thousand gold is unknown. In addition, if you want to obtain the price of the refined price, you can test the general factors, according to the market conditions below.
    What are the storage conditions for 4-bromo-6-chloro-2-pyridinecarboxylic acid?
    4-Bromo-6-chloro-2-pyridinecarboxylic acid is an extremely important organic compound, which is widely used in many fields such as medicine, pesticides, materials, etc. Its storage conditions are crucial, which is related to the stability and quality of the compound.
    According to the text of "Tiangong Kaiwu", this compound should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, high temperature and humid environment are prone to chemical reactions and affect quality. Therefore, it is necessary to ensure that the temperature of the storage environment is moderate and the humidity is low to prevent moisture decomposition and deterioration.
    Furthermore, 4-bromo-6-chloro-2-pyridinecarboxylic acid should be stored separately from oxidizing agents, acids, bases and other substances. Due to the chemical structure of the compound, it may react violently with the above substances, causing safety accidents. And the storage area should be equipped with suitable materials to contain leaks, so as to prevent accidental leakage and timely treatment to avoid harm to the environment and personnel.
    In addition, the choice of storage container is also very critical. It is advisable to use containers with good sealing performance, such as glass bottles or plastic bottles of specific materials, to ensure that the container can effectively isolate air and moisture, and further maintain the stability of the compound. During storage, it is also necessary to check it regularly to see if there are any abnormal phenomena such as deterioration and leakage, so as to detect and deal with problems in time. In this way, 4-bromo-6-chloro-2-pyridinecarboxylic acid can be properly stored to ensure its quality and performance.