2 Pyridinecarbonitrile 5 Bromo 3 Methyl
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinecarbonitrile,5-bromo-3-methyl-

    Specifications

    HS Code

    324637

    Chemical Formula C7H5BrN2
    Molecular Weight 197.03 g/mol
    Appearance Solid
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane

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    Frequently Asked Questions

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    2-Pyridinecarbonitrile, what are the physical properties of 5-bromo-3-methyl-
    2-Pyridyl formonitrile, 5-bromo-3-methyl, its physical properties are particularly important and are fundamental to many chemical applications. In terms of its color state, it often shows a crystalline powder like white to yellowish at room temperature, with a fine texture. It looks like fine sand grains are gathered in one place, with a pure color and no variegated patches.
    As far as the melting point is concerned, it is about a specific value range. This value is an inherent property of the substance, like a human fingerprint, which is the key to its identification. When heated to this melting point, the substance gradually melts from the solid state to the liquid state. This phase transition process occurs quietly, just like ice and snow melting in the warm sun, and the transformation of the state of matter is completed at a specific temperature node.
    Solubility is also its significant physical property. In common organic solvents, such as ethanol and acetone, this substance exhibits good solubility, just like a fish entering water, it can quickly disperse and form a uniform solution. However, in water, its solubility is relatively limited, and it seems to be water-repellent, only slightly soluble, making it difficult to blend intimately with water.
    In addition, its density also has a certain value. Although it is not as heavy as gold and iron, it provides an important basis for accurate control of the dosage in chemical experiments such as weighing and mixing. Its density is like an invisible ruler, measuring the proportion of matter in space, and affecting the process and result of the reaction at the microscopic level. The various physical properties complement each other, and together outline the unique physical appearance of 2-pyridinonitrile and 5-bromo-3-methyl, which lays a solid foundation for chemists to explore their chemical behavior and applications.
    2-Pyridinecarbonitrile, what are the chemical properties of 5-bromo-3-methyl-
    2-Pyridineformonitrile, 5-bromo-3-methyl This substance has many chemical properties. Its appearance may be a crystalline powder, due to the unique properties of nitrile groups, bromine atoms and methyl groups.
    Nitrile groups have high reactivity and can undergo hydrolysis reactions. Under acidic or basic conditions, they can be gradually converted into carboxylic acids or carboxylic salts. They can also undergo addition reactions with nucleophiles to generate various nitrogen-containing derivatives, which are of great significance in the construction of complex organic molecular structures.
    Bromine atoms, as active halogen atoms, are prone to participate in nucleophilic substitution reactions. Under suitable reaction conditions and the action of nucleophiles, bromine atoms can be replaced by other groups, such as hydroxyl and amino groups, to introduce different functional groups and expand the application range of compounds. At the same time, bromine atoms can also participate in metal-catalyzed coupling reactions, such as Suzuki coupling, Stille coupling, etc., to help build carbon-carbon bonds and synthesize complex organic conjugated systems, which may have potential uses in the field of materials science.
    methyl is the power supply group. Although its chemical activity is slightly lower than that of nitrile and bromine atoms, it can affect the distribution of molecular electron clouds, change molecular polarity and spatial structure, and then affect the physical and chemical properties of compounds, such as their melting point, boiling point and solubility. The activity and selectivity of electrophilic substitution reactions on aromatic rings are affected by the action of methyl power supply or the increase of electron cloud density in ortho or para-position.
    In summary, the interaction of functional groups contained in 2-pyridinonitrile and 5-bromo-3-a genes shows diverse chemical properties and shows broad application prospects in organic synthesis, medicinal chemistry, materials science and other fields.
    2-Pyridinecarbonitrile, what is the main use of 5-bromo-3-methyl-
    2-Pyridineformonitrile, 5-bromo-3-methyl, has a wide range of uses in today's world. In the field of medicinal chemistry, it is a key intermediate for the preparation of specific drugs. Due to its unique chemical structure, it can be combined with other chemicals through various chemical reactions and ingenious combination methods to make drugs with excellent efficacy for specific diseases.
    In the field of materials science, it also has great value. Due to its unique chemical properties, it may participate in the material synthesis process and endow materials with special properties, such as improving the stability, conductivity or optical properties of materials. In this way, advanced materials suitable for special needs may be developed, which will make a name for themselves in industries such as electronic devices and optical instruments.
    Furthermore, in the field of organic synthetic chemistry, it is often used as an important raw material. The subtlety of organic synthesis lies in the ingenious design of reaction paths, and this substance can be used as a starting material due to its own structural characteristics. Through various reaction steps, complex organic molecular structures can be constructed. Chemists have used their exploration of many innovative synthetic routes to contribute to the development of organic chemistry.
    In conclusion, 2-pyridinonitrile, 5-bromo-3-methyl play an important role in many fields such as medicine, materials and organic synthesis, and play an indispensable role in the progress of modern chemical technology.
    2-Pyridinecarbonitrile, what are the synthesis methods of 5-bromo-3-methyl-
    There are various methods for preparing 2-pyridylmethonitrile and 5-bromo-3-methyl. The common method is to take a suitable pyridine derivative as the starting material. If 3-methylpyridine is used as the base, and the bromine atom is introduced at its 5th position, the method of bromination can be selected. Using liquid bromine as the bromine source, accompanied by a suitable catalyst, such as iron powder or iron tribromide, at a suitable temperature and reaction environment, bromine and 3-methylpyridine undergo electrophilic substitution reaction to obtain 5-bromo-3-methylpyridine.
    Then, to introduce a cyanyl group into the second position of pyridine, a halogenated pyridine can be used to react with a cyanide reagent. Common cyanide reagents such as cuprous cyanide are heated in a specific solvent, such as N, N-dimethylformamide (DMF), to promote the reaction, so that the halogen atom is replaced by a cyanyl group, and the final product is 2-pyridine formonitrile and 5-bromo-3-methyl.
    Or take a different approach, use the pyridine derivative containing cyanide as the starting material, first prepare a cyanide-containing pyridine compound with a suitable substituent, and then introduce 5-bromo atoms through the bromination step. However, this process needs to be controlled by paying attention to the conditions of each step of the reaction, such as temperature, reaction time, reagent dosage, etc., to ensure a smooth reaction, pure product and considerable yield. Each method has its own advantages and disadvantages, and it is necessary to choose a good method according to the actual situation, such as the availability of raw materials, cost, and product purity.
    2-Pyridinecarbonitrile, what are the precautions for 5-bromo-3-methyl- during use?
    2-Pyridyl-formonitrile, 5-bromo-3-methyl When using this compound, many things need to be paid attention to.
    First, safety is the key. This compound may be toxic and irritating. When handling, be sure to wear appropriate protective equipment, such as gloves, goggles, lab clothes, etc., to prevent direct contact with the skin and eyes, and work in a well-ventilated place to avoid inhaling its dust or volatile gases. If you are accidentally exposed, you should immediately rinse with plenty of water and seek medical assistance according to the specific situation.
    Second, its chemical properties cannot be ignored. Because it contains active groups such as nitrile groups and bromine atoms, its chemical activity is quite high. When storing, it is necessary to keep away from fire sources, heat sources, strong oxidants, strong acids, strong bases, etc., to prevent violent chemical reactions from occurring and causing danger. When taking it, the operation should be precise and meticulous to avoid deterioration of substances or other accidents caused by improper operation.
    Third, in view of its important intermediates in organic synthesis, in the synthesis reaction, the reaction conditions are strictly required. Factors such as temperature, reaction time, and the proportion of reactants all have a profound impact on the reaction results. Therefore, the reaction conditions need to be carefully optimized according to the specific reaction to achieve the expected synthesis goal.
    Fourth, after use, the disposal of its waste should not be taken lightly. It is necessary to follow relevant environmental protection regulations, take proper disposal methods, and must not be discarded at will to avoid pollution to the environment. < Br >
    The operation of this object requires rigorous and meticulous attention from beginning to end, and great attention is paid to safety and specifications to ensure the smooth progress of the experiment or production.