2 Pyridinecarbonitrile 3 Nitro
pyridine pyrrole pyrazine piperidine piperazine

2-Pyridinecarbonitrile, 3-nitro-

    Specifications

    HS Code

    390788

    Chemical Formula C6H3N3O2
    Molecular Weight 149.11 g/mol
    Appearance Solid
    Melting Point 168 - 170 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
    Hazard Class Irritant

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    Frequently Asked Questions

    As a leading 2-Pyridinecarbonitrile, 3-nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    2-Pyridinecarbonitrile, what are the chemical properties of 3-nitro-
    2-Pyridineformonitrile, 3-nitro, is an organic compound. It has unique chemical properties. The physical properties of this substance, at room temperature or as a solid, have a specific color and taste, but the details depend on the experiment.
    In terms of chemical activity, its nitrile group (-CN) and nitro group (-NO) are both active functional groups. Nitrile groups can participate in a variety of reactions, such as hydrolysis to obtain pyridineformic acid, which can be induced under suitable acid-base conditions. The presence of nitro groups changes the distribution of molecular electron clouds and enhances its electrophilicity.
    Its chemical properties make it important in the field of organic synthesis. It can be used as a key intermediate to prepare a variety of nitrogen-containing heterocyclic compounds through a series of reactions. And due to the special reactivity of nitrile and nitro groups, it can provide a way to construct complex organic structures.
    Furthermore, due to its nitrogen and unsaturated bonds, it may have potential applications in materials science, pharmaceutical chemistry and other fields. However, its reactivity also needs to be treated with caution, and safety procedures must be followed during experimental operations to prevent dangerous reactions and ensure a smooth and safe synthesis process.
    2-Pyridinecarbonitrile, what are the physical properties of 3-nitro-
    2-Pyridineformonitrile, 3-nitro, is a kind of organic compound. Its physical properties are quite important, let me talk about them one by one.
    First of all, its appearance, at room temperature, is mostly solid, and often powdery, fine texture, or a light yellow color. Although this color is not gorgeous, it also shows its unique nature.
    As for the melting point, it has been explored by many parties and is about a specific temperature range. When the external temperature gradually rises to a certain value, this substance will gradually melt from the solid state and turn into a liquid state. The number of melting points is crucial to understanding its essence and characteristics.
    Furthermore, its solubility is also the key. In organic solvents, such as common ethanol, acetone, etc., it has a certain solubility. This property is very useful in many chemical processes and can help in separation, purification and other operations. However, in water, its dissolution is quite difficult, only slightly soluble. Due to the molecular structure, the interaction with water molecules is relatively weak.
    Its density is also an important physical property. After precise measurement, its specific value can be obtained. This density, in many chemical experiments and industrial production, can help to accurately calculate the dosage and control the reaction process.
    The volatility of this substance is low, and it is not easy to dissipate in the air under normal temperature and pressure. This property not only makes it more stable during storage and use, but also reduces the risk and loss caused by volatilization.
    In summary, 2-pyridineformonitrile and 3-nitro have unique physical properties and are of great value in the research and application of chemistry.
    2-Pyridinecarbonitrile, what is the main use of 3-nitro-
    2-Pyridineformonitrile, 3-nitro This compound has a wide range of uses. In the field of chemical industry, it is often used as a key intermediate in organic synthesis. With its unique chemical structure, it can participate in many delicate chemical reactions and help build various complex organic compounds.
    In the field of pharmaceutical research and development, it also plays an important role. It can be used as a starting material, through a series of ingenious transformations, to synthesize compounds with specific pharmacological activities, laying the foundation for the creation of new drugs, which are expected to be used to solve various diseases.
    In the field of materials science, it can be introduced into polymer materials through specific reactions, thereby improving material properties, such as improving material stability, mechanical properties, etc., making materials more suitable and superior in different application scenarios. Such a variety of uses make it indispensable in many fields, driving the continuous development and progress of various fields.
    2-Pyridinecarbonitrile, what are the synthesis methods of 3-nitro-
    The synthesis method of 2-pyridineformonitrile and 3-nitro can be started from pyridine. Take pyridine first, put it in an appropriate reaction vessel, and add an appropriate amount of nitrifying reagent, such as the mixed acid of concentrated nitric acid and concentrated sulfuric acid. Under the condition of low temperature and careful temperature control, slowly add the mixed acid dropwise. Due to the violent nitrification reaction, careful operation is required to prevent runaway. The electron cloud distribution on the pyridine ring makes it easy for the nitro to be replaced in the 3-position. After a period of reaction, the reaction progress is monitored by thin-layer chromatography and other means. When the reaction reaches the expected level, the reaction liquid is carefully poured into the ice water to stop the reaction and promote the precipitation of the product. Next, the organic phase is extracted with an appropriate organic solvent, such as dichloromethane, and dried with a desiccant such as anhydrous sodium sulfate. Subsequently, the solvent is removed by reduced pressure distillation, and the crude product is further purified by column chromatography. A suitable eluent is selected to obtain pure 3-nitropyridine.
    Then, 3-nitropyridine is reacted with a cyanide reagent, such as cuprous cyanide, in a specific organic solvent, such as N, N-dimethylformamide (DMF), at a suitable temperature and in the presence of a catalyst. Continuous stirring is required during the reaction to ensure full contact of the reactants. The reaction was also monitored by thin layer chromatography. When the reaction was completed, the reaction liquid was cooled, diluted with water, and then extracted with an organic solvent to separate the organic phase. After drying, it was purified by reduced pressure distillation and column chromatography to obtain 2-pyridinonitrile and 3-nitro products. In this way, the synthesis of 2-pyridinitrile and 3-nitro was achieved through two-step reaction of nitrification and cyanide.
    2-Pyridinecarbonitrile, 3-nitro - what to pay attention to when storing and transporting
    2-Pyridineformonitrile, 3-nitro This substance, when storing and transporting, need to pay attention to many matters. It is a chemical substance with specific chemical properties and latent risks.
    When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. Because the substance may be sensitive to heat, humidity, high temperature and humidity, or cause its chemical properties to change, and even cause dangerous reactions. And should be kept away from fire, heat sources, open flames and hot topics or cause them to burn and explode.
    Furthermore, storage needs to be classified and stored. Do not mix with oxidants, acids, alkalis, etc., because of their chemical activity, contact with these substances, or react violently. At the same time, the storage area should be equipped with suitable containment materials to prevent leakage accidents, timely treatment, control the spread of hazards.
    When transporting, the packaging must be solid. Ensure that the container is well sealed and there is no risk of leakage. The selected packaging materials must be able to withstand bumps and vibrations during transportation. Transportation vehicles must also meet safety standards and be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment.
    Transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. During driving, avoid violent operations such as sudden braking and sharp turning to prevent package damage. And the transportation route should avoid sensitive areas such as densely populated areas and water sources to reduce the impact of accidents. In this way, the safety of 2-pyridinonitrile and 3-nitro is guaranteed during storage and transportation.