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What are the main uses of 2-PYRIDINECARBONITRILE, 3,5-Dichloro-?
3,5-Dichloro-2-pyridineformonitrile is widely used. In the field of pharmaceutical synthesis, it is an important intermediate. Many drugs with special curative effects are often synthesized from 3,5-dichloro-2-pyridineformonitrile. Through a series of delicate chemical reactions, complex molecular structures with specific pharmacological activities can be constructed, and then therapeutic drugs for various diseases can be developed.
In the creation of pesticides, 3,5-dichloro-2-pyridineformonitrile also plays a key role. With its unique chemical structure, many high-efficiency pesticide ingredients can be derived. Such pesticides either have strong killing ability against specific pests, or have significant control effects on certain plant diseases, providing strong support for the control of pests and diseases in agricultural production.
In the field of materials science, this compound also shows potential application value. After specific treatment and modification, it may participate in the preparation of new materials. Or improve the stability and functionality of materials, providing new ideas and approaches for the innovation and development of materials science. In short, 3,5-dichloro-2-pyriformonitrile has important uses in many fields and plays an indispensable role in promoting the development of related industries.
What are the physical properties of 2-PYRIDINECARBONITRILE, 3,5-Dichloro-?
3,5-Dichloro-2-pyridineformonitrile, this is an organic compound. Its physical properties are quite unique and it is widely used in the field of organic synthesis.
Let's talk about the appearance first. At room temperature, 3,5-dichloro-2-pyridineformonitrile is often in the state of white to light yellow crystalline powder. When it is pure, the color is uniform and the particles are fine. This form is easy to store, transport and subsequent use. Because its powder shape can increase the contact area with other substances, it is conducive to the progress of chemical reactions.
Let's talk about the melting point. After many experiments, its melting point is about 105-109 ° C. Melting point is one of the important physical properties of a substance, which can help to identify its purity. If the measured melting point matches the standard value and the melting range is narrow, it usually indicates that the purity of the substance is quite high; conversely, if the melting point deviates or the melting range is too wide, it may contain impurities.
When it comes to solubility, this compound exhibits different solubility characteristics in common organic solvents. In halogenated hydrocarbon organic solvents such as dichloromethane and chloroform, it has good solubility and can quickly dissolve to form a uniform solution. In polar aprotic solvents such as N, N-dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), it also has good solubility. However, in water, the solubility of 3,5-dichloro-2-pyridineformonitrile is very small, because there are few polar groups in the molecular structure and the force between water molecules is weak, so it is difficult to dissolve.
In addition, the density of 3,5-dichloro-2-pyridineformonitrile is moderate. Although the exact density data will vary slightly due to measurement conditions, it is roughly within a certain range. This property is of great significance for material measurement and reaction system ratio in industrial production and laboratory operations.
In summary, the physical properties of 3,5-dichloro-2-pyridineformonitrile, from appearance, melting point, solubility to density, are related to each other and affect their application in organic synthesis, pharmaceutical and chemical fields. Understanding these properties can better control this compound and lay the foundation for research and production in related fields.
What are the chemical properties of 2-PYRIDINECARBONITRILE, 3,5-Dichloro-?
3,5-Dichloro-2-pyridylmethonitrile, this is an organic compound. Looking at its structure, there are chlorine atoms and cyanyl groups at specific positions on the pyridine ring, and this structure gives it unique chemical properties.
In terms of its physical properties, it may be a solid under normal conditions, with a certain melting point and boiling point. Because the molecule contains a polar group cyanyl group, it may have a certain solubility in polar solvents, but it may have limited solubility in non-polar solvents.
In terms of chemical properties, cyanyl groups have high activity and can participate in many chemical reactions. If under suitable conditions, cyanyl groups can be hydrolyzed into carboxyl groups to obtain corresponding pyridine carboxylic acids; it can also be reduced to form amine groups to obtain pyridine derivatives containing amine groups. The chlorine atom on the pyridine ring can undergo nucleophilic substitution reaction. Under the action of bases or nucleophiles, the chlorine atom can be replaced by other groups, thereby expanding the diversity of molecular structures.
In addition, in view of the conjugation system of the pyridine ring, this compound may have certain stability and electron delocalization characteristics, which affect its chemical activity and reaction selectivity. Due to its unique chemical properties, it is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various drugs, pesticides and functional materials.
What are the synthesis methods of 2-PYRIDINECARBONITRILE, 3,5-Dichloro-
There are various methods for the synthesis of Fu 3,5-dichloro-2-pyridyl methanonitrile. The following are common methods:
First, 3,5-dichloropyridine is used as the starting material. First, it reacts with suitable reagents and introduces cyanyl groups. It is often reacted with metal cyanides, such as cuprous cyanide, in an organic solvent under suitable reaction conditions. This reaction requires control of factors such as temperature and reaction time. If the temperature is too high, or side reactions increase, the product is impure; if the temperature is too low, the reaction rate will be slow and take a long time. The reaction time also needs to be precisely controlled. If it is too short, the reaction will be incomplete, and if it is too long, it may lead to overreaction. In this process, the choice of organic solvent is also crucial, which needs to be able to dissolve the reactants without adverse effects on the reaction, such as N, N-dimethylformamide (DMF), etc., because of its good solubility and relatively stable chemical properties, it is often preferred.
Second, it can be started from 3,5-dichloro-2-pyridinecarboxylic acid. First convert it into the corresponding acid chloride, and common chlorination reagents such as dichlorosulfoxide react with it to generate 3,5-dichloro-2-pyridinecarboxylic chloride. This step requires attention to the amount of chlorination reagent and reaction conditions to ensure high yield of acid chloride. Then, the resulting acid chloride is reacted with a cyanide reagent, such as sodium cyanide, in an appropriate reaction system to obtain 3,5-dichloro-2-pyridyl formonitrile. In this process, the intermediate products of each step of the reaction need to be properly handled to ensure the purity and yield of the final product.
Or there may be a method of using other related compounds as starting materials through multi-step reactions. However, no matter what method, the conditions of each reaction step, the selection and dosage of reagents need to be carefully considered, and the reaction process needs to be closely monitored to achieve the purpose of efficient synthesis of 3,5-dichloro-2-pyridyl formonitrile.
2-PYRIDINECARBONITRILE, 3,5-Dichloro - in which areas are they used?
3,5-Dichloro-2-pyridinecarbonitrile, which is used in many fields.
In the field of medicine, it is a key class of pharmaceutical intermediates. Through specific chemical reactions, it can be converted into bioactive compounds, which can be used to develop new drugs. For example, in the creation of antibacterial drugs, its unique chemical structure can be combined with specific targets in bacteria to hinder the normal physiological metabolism of bacteria, thereby exerting antibacterial effects and providing a strong basis for drug development against bacterial infections.
In the field of pesticides, it also plays an important role. Using it as a starting material, a variety of highly efficient pesticide products can be prepared. For example, some pesticides achieve efficient pest control by precisely acting on the nervous system or physiological and metabolic pathways of pests, and have a relatively small impact on the environment. They help agricultural production to achieve green and efficient pest prevention and control, and ensure the yield and quality of crops.
In the field of materials science, 3,5-dichloro-2-pyridineformonitrile also shows unique value. It can participate in the synthesis process of functional materials, such as some materials with special optical and electrical properties. By ingeniously introducing it into the molecular structure of materials, novel physical and chemical properties are endowed to materials, opening up new paths for the development and application of new materials, and has potential application prospects in electronic devices, optical displays, etc.