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What is the main use of 2-pyridinebutanoic acid?
2-Pyridinobutyric acid has a wide range of uses. In the field of pharmaceutical research and development, this substance is often used as a key intermediate. Due to the unique structure of pyridine and butyric acid, it can be converted into compounds with specific pharmacological activities by chemical modification and synthesis pathways. Such as the creation of many targeted drugs, 2-pyridinobutyric acid can undergo complex reactions to construct structures that fit the target of diseased cells, achieving the effect of precision therapy.
In the chemical industry, it is also indispensable. It can participate in the synthesis of polymer materials, and by means of its active groups, it can be copolymerized with other monomers to improve material properties. For example, the preparation of polymers with special adsorption or stability is used for adsorption separation, slow-release carriers, etc. Its structural properties endow materials with unique physical and chemical properties, expanding the scope of material applications.
In the field of agricultural chemicals, 2-pyridyl butyric acid is also involved. It can be modified and derived into biologically active substances, such as as plant growth regulators. It can regulate the process of plant growth and development, affect the balance of plant hormones, promote physiological processes such as rooting, flowering, and fruiting, and improve crop yield and quality.
Furthermore, in organic synthetic chemistry, 2-pyridyl butyric acid is an important raw material and reagent. Because it contains active functional groups, it can participate in a variety of organic reactions, such as esterification, amidation, etc. By ingeniously designing reaction routes, complex organic molecular structures can be constructed, providing a basis for organic synthetic chemists to explore new compounds.
What are the physical properties of 2-pyridinebutanoic acid
2-Pyridinobutyric acid is a kind of organic compound. Its physical properties are quite unique, under normal temperature and pressure, it usually appears as a solid state. Looking at its color, or white to light yellow, the appearance is often crystalline powder, fine texture.
When it comes to the melting point, the melting point of this substance is in a specific range, about [X] ° C. The characteristics of the melting point are crucial in the identification and purification of this compound. Due to the different purity of 2-pyridinobutyric acid, its melting point may be slightly different, and its purity can be judged by accurately measuring the melting point.
Furthermore, 2-pyridinobutyric acid also has characteristics in terms of solubility. Its solubility in water is limited, but some organic solvents, such as ethanol and acetone, exhibit good solubility. This property makes it possible to choose suitable solvents for dissolution, separation and reaction operations according to requirements in relevant chemical experiments and industrial production.
In addition, the density of this compound is also an important physical property. Its density is about [X] g/cm ³, which is of great significance for accurate measurement and control of its dosage during preparation and use. The stability of density helps to ensure the accuracy and consistency of chemical reactions.
To sum up, the physical properties of 2-pyridyl butyric acid, such as appearance, melting point, solubility, and density, play an indispensable role in chemical research, chemical production, and many other fields, providing a solid foundation for in-depth exploration of its chemical properties and practical applications.
What are the chemical properties of 2-pyridinebutanoic acid
2-Pyridine butyric acid is also an organic compound. It has unique chemical properties, let me tell you one by one.
Looking at its structure, it contains a pyridine ring and a side chain of butyric acid, which gives it unique properties. In terms of physical properties, it is mostly solid at room temperature, and it shows a certain solubility in organic solvents, such as ethanol and ether, etc., but its solubility in water is slightly inferior.
In terms of chemical properties, pyridine rings are electron-rich systems, aromatic, and can undergo a variety of electrophilic substitution reactions. For example, when encountering electrophilic reagents, they can be substituted at specific positions of the pyridine ring, such as the 3-position or the 4-position, to generate new derivatives. < Br >
The carboxyl group of the side chain of butyric acid has the properties of a typical carboxylic acid. It can neutralize with bases to form corresponding carboxylic salts. If it is catalyzed by acids, it can be esterified with alcohols to form ester compounds. This reaction is used in organic synthesis and is often used to prepare esters with specific functions.
In addition, the pyridine ring nitrogen atom of this compound has lone pairs of electrons and can be used as a ligand to coordinate with metal ions to form metal complexes. This property has potential application value in the field of materials science and catalysis. < Br >
Because its structure contains both aromatic rings and carboxyl groups, it can participate in a variety of condensation reactions. With compounds containing amino or hydroxyl groups, through condensation, more complex organic molecular structures can be constructed. It has important applications in drug synthesis and the preparation of functional materials.
What are the synthesis methods of 2-pyridinebutanoic acid
The synthesis method of 2-pyridine butyric acid has been known in ancient times, and there are many methods, each with its own strengths.
First, pyridine and halobutyrate are used as raw materials, and they are prepared by nucleophilic substitution reaction. The halogen activity of halobutyrate is very good, and the nitrogen atom of pyridine is nucleophilic. When the two meet, such as yin and yang fit, the halogen leaves, and the pyridine is connected, so it becomes pyridine butyrate. After hydrolysis, the ester bond is broken to obtain 2-pyridine butyric acid. This process requires the selection of suitable solvents and bases to promote the smooth progress of the reaction.
Second, starting from 2-methylpyridine, first through side chain halogenation, introducing halogen atoms, and then through cyanide and hydrolysis steps. When side chain halogenation, the conditions need to be precisely controlled to make the halogen positioning accurate. In one step of cyanidation, the cyanyl group replaces the halogen, increases the carbon chain, and then hydrolyzes, and the cyanyl group is converted into a carboxyl group to obtain the target product.
Third, the method of organometallic reagents can be used. For example, pyridine halide interacts with metal reagents such as butyl lithium to form an active intermediate, and then reacts with carbon dioxide to introduce a carboxyl group. After subsequent treatment, 2-pyridyl butyric acid is obtained. This process requires strict reaction conditions, and an anhydrous and anaerobic environment is indispensable to maintain the activity of metal reagents.
All such synthesis methods need to be carefully selected according to factors such as the availability of raw materials, cost considerations, difficulty of reaction, and high or low yield, in order to obtain satisfactory results.
What is the price range of 2-pyridinebutanoic acid in the market?
The price of 2-pyridinobutyric acid is difficult to say in a word. The price of 2-pyridinobutyric acid is often changed due to many reasons, such as the quality of the product, the state of supply and demand, the place of production, and the time difference.
If the quality is excellent, it is made by using exquisite methods, pure and flawless, and impurities are rare, and the price must be high. And if the quality is slightly inferior, the price may be lower. When the supply exceeds the demand, the merchant wants to sell the goods quickly, and the price often drops; if the demand exceeds the supply, and everyone bids, the price will rise.
The origin is also the main reason. The production is convenient, the material is easy to obtain, the labor cost is saved, and the price is cheap; if the place is remote, the mining and transportation are difficult, and the cost is huge, the price will be high. The passage of time can also move the price. In the season when the raw materials are abundant, the production is easy, and the price is flat; when the raw materials are rare, the cost increases, and the price must rise.
Roughly speaking, in today's city, the price of 2-pyridinobutyric acid ranges from a few yuan to tens of yuan per gram. Small retail sales, the price may be high; if you buy in large quantities, the merchant may give a discount, and the price is slightly lower. However, this is only an approximate number, and the actual price must be consulted in detail, depending on the real-time situation. If you want to know the exact price, you must carefully investigate the market and negotiate with various merchants before you can be sure.