2-(Pyridin-3-yl)acetamide

2-%28Pyridin-3-yl%29acetamide, in ancient Chinese, this is one of the organic compounds. Its chemical structure can be detailed as follows:
The core of this compound is a pyridine ring, and the pyridine is a nitrogen-containing hexamembered heterocyclic compound. It has unique properties and aromatic properties. Its 3-position is connected with an acetamide group.
In the pyridine ring, the nitrogen atom is bonded with a sp ² hybrid orbit, and together with the other five carbon atoms form a planar structure. There is a large π bond in the ring, which makes the pyridine have certain stability and special chemical activity.
The acetamide group is connected, among which the carbonyl group (C = O) has a strong polarity, the nitrogen atom is connected to the carbonyl carbon, and the amide group can participate in the formation of hydrogen bonds. The methylene group of the acetyl group (-CH 2O -) connects the pyridine ring and the amide group, which plays a bridge role and affects the overall spatial structure and chemical properties of the molecule.
The chemical structure of this compound makes it have the characteristics of both pyridine ring and amide group, and may have unique uses and reactivity in organic synthesis, medicinal chemistry and other fields.

2-%28Pyridin-3-yl%29acetamide is 2- (pyridine-3-yl) acetamide, which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. In many drug development processes, it is like a cornerstone of a grand building, laying the foundation for the creation of new drug molecular architectures. In terms of innovative drug synthesis for the treatment of specific diseases, 2- (pyridine-3-yl) acetamide can use its unique chemical structure, through a series of delicate chemical reactions, cleverly linked with other active groups, to construct compounds with specific pharmacological activities, or with antibacterial, antiviral, antitumor and other effects.
In the field of materials science, it also has good performance. In the preparation of some functional polymer materials, 2 - (pyridine-3-yl) acetamide can participate in the polymerization reaction, giving the material special properties. For example, the material has better solubility, thermal stability, or exhibits excellent adsorption capacity for specific substances, so that the material can be used in many fields such as separation membranes, adsorbents and so on.
In the field of organic synthesis, it is an extremely important building block. Organic chemists can achieve efficient construction of various complex organic compounds by chemically modifying it. It is like a multi-functional tool in the hands of a skilled craftsman, capable of assisting in the completion of various delicate and complex synthesis tasks, expanding the variety and structural diversity of organic compounds, and injecting a steady stream of vitality into the vigorous development of organic synthetic chemistry.

To prepare 2- (pyridine-3-yl) acetamide, there are many methods, which are described in detail as follows.
First, it can be obtained by hydrolysis of 3-pyridine acetonitrile. Take an appropriate amount of 3-pyridine acetonitrile, place it in a reaction kettle, add an appropriate amount of acid or alkali aqueous solution, such as hydrochloric acid or sodium hydroxide solution. When acid catalyzes, hydrogen ions in the kettle promote the hydrolysis of nitrile groups, and first form amide intermediates to obtain 2 - (pyridine-3-yl) acetamide; alkali catalyzes the action of hydroxide ions on nitrile groups and follow a similar path to form products. The reaction needs to be temperature controlled. Depending on the catalyst used, the temperature may be between tens of degrees Celsius and hundreds of degrees Celsius, and the duration should also be adjusted accordingly, ranging from a few hours to even tens of hours. After the reaction is completed, the product can be purified by extraction, distillation, and recrystallization.
Second, it can be prepared by reacting 3-pyridyl acetic acid with ammonia. In the reaction vessel, 3-pyridyl acetic acid is placed and ammonia gas is introduced. To promote the reaction, a shrinking agent, such as dicyclohexyl carbodiimide (DCC), can be added. Under the action of DCC, the carboxyl group of the acid interacts with ammonia to dehydrate into an amide bond to obtain the target product. This reaction also needs to be temperature controlled, usually between room temperature and tens of degrees Celsius After the reaction is completed, it is separated and purified by steps such as filtration to remove the by-products of the condensation agent, and then the purified product is obtained by chromatography and crystallization.
Third, 3-pyridyl ethanol can be obtained by a series of reactions. First, 3-pyridyl ethanol is oxidized to 3-pyridyl acetaldehyde with a suitable oxidant, such as chromium trioxide-pyridyl complex, followed by an oxidant, such as potassium permanganate or hydrogen peroxide, and further oxidized to 3-pyridyl acetic acid, and then according to the above method of reacting the acid with ammonia to form 2 - (pyridyl-3-yl) acetamide. Each step of the reaction needs to be carefully controlled, and the oxidation step needs to pay attention to the temperature and the amount of oxidant to prevent excessive oxidation. After each step of the reaction, it also needs to be properly purified to ensure the smooth subsequent reaction and finally obtain pure 2- (pyridine-3-yl) acetamide.

2-%28Pyridin-3-yl%29acetamide, organic compounds are also. Its physical properties are particularly important, related to many uses and properties of this substance.
First of all, its properties, under room temperature and pressure, are mostly white to white crystalline powders. This form is easy to store and use, and the crystalline structure also affects its chemical stability and reactivity. Looking at its color, it is white and pure, and there is little variegation, which shows that its purity is quite high.
When it comes to melting point, 2-%28Pyridin-3-yl%29acetamide a specific melting point range, usually in a certain temperature range. The determination of melting point can determine its purity. The higher the purity, the narrower the melting point range and approaching the theoretical value. This property plays a significant role in the identification and quality control of compounds.
Solubility is also a key physical property. In common organic solvents, such as ethanol, methanol, etc., 2-%28Pyridin-3-yl%29acetamide have a certain solubility. This solubility makes it participate in many chemical reactions in the form of solutions, or in pharmaceutical preparations, to help it disperse and absorb. However, the solubility in water is relatively limited, which is due to the characteristics of molecular structure, the balance of hydrophilic groups and hydrophobic groups.
Furthermore, the density of this substance is established, although it is not the focus of daily attention. However, in the fields of chemical production, mass measurement and other fields, accurate density determination provides key data for material ratio and reactor design.
2-%28Pyridin-3-yl%29acetamide has various physical properties, and each property is interrelated, which jointly determines the application and characteristics of this substance in different fields. Properties such as properties, melting point, solubility, and density lay a solid foundation for research and practice in scientific research, production, and medicine.

I am not sure about the price range of 2 - (pyridine-3-yl) acetamide on the market. The price of this compound is affected by many factors, and it is difficult to generalize.
First, the purity has a great impact. If its purity is extremely high, it is almost scientific-grade pure, and it is used in laboratory precision experiments, the price will be high. Because of its complicated purification process, it consumes a lot of manpower, material resources and financial resources. However, if the purity is slightly lower, it is suitable for general industrial use, and the price may be relatively low.
Second, the purchase quantity is also the key. For bulk purchases, due to the scale effect, the unit price may be favorable. For small purchases, merchants may price higher due to transaction costs.
Third, the market supply and demand situation determines the price. If the demand for this compound is strong and the supply is limited, if there is a large demand in a specific industry, the price will rise. On the contrary, if the supply exceeds the demand, the price will easily fall.
Fourth, different suppliers have different pricing strategies. Well-known and reputable suppliers may have high prices due to stable product quality and high service. And some emerging or small suppliers may be more affordable in order to compete for market share. Therefore, if you want to know the exact price range of 2 - (pyridine - 3 - yl) acetamide, you need to consult the relevant chemical product suppliers in detail, or check the chemical product trading platform carefully, and integrate multiple parties' information to obtain a more accurate price range.