2-Phenyl-3H-imidazo[4,5-b]pyridine

2-Phenyl-3H-imidazolo [4,5-b] pyridine is an organic compound. It has a wide range of uses in the field of medicine and is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms. By modifying its structure, it is expected to develop specific drugs for specific diseases, such as cancer and neurological diseases.
In the field of materials science, it also has important uses. It can be used as a basic unit for the construction of new functional materials, endowing materials with unique properties such as fluorescence and conductivity, and may play an important role in organic Light Emitting Diode (OLED), sensors, etc.
In addition, in the field of chemical research, it is an important research object in organic synthetic chemistry. Chemists use various chemical reactions to explore novel synthesis methods and reaction mechanisms to promote the development of organic chemistry. In short, 2-phenyl-3H-imidazolo [4,5-b] pyridine has important value in many fields, and its potential uses may be further expanded with the deepening of research.

2-Phenyl-3H-imidazolo [4,5-b] pyridine, this material property is special, and it is related to the mystery of chemistry. Its color state, mostly solid at room temperature, is like a fine powder, and the pure one is white and flawless, just like the purity of winter snow.
Looking at its melting point, the melting point is quite high, and it needs intense heat to melt. This is due to the strong intermolecular force and stable structure. As for the boiling point, it is also at a high level, and it needs to be extremely hot to vaporize into steam.
Solubility is also important for physical properties. In water, it dissolves very little, because its molecular polarity is weak, it is very different from that of water, and it is difficult to dissolve. However, organic solvents, such as dichloromethane, chloroform, etc., dissolve quite well, due to the principle of "similar miscibility", such organic solvents are similar to 2-phenyl-3H-imidazolo [4,5-b] pyridine molecules in polarity and can dissolve and blend with each other.
Its density is higher than that of common solvents, and it is placed in a liquid and often sinks at the bottom. And it has certain stability, and it is not easy to decompose and deteriorate under ordinary conditions. In case of extreme conditions such as strong acid, strong base or high temperature, strong oxidant, etc., the molecular structure may be damaged, causing chemical changes.
The physical properties of this substance are the cornerstone of chemical research and application, assisting chemists in understanding its characteristics, and then being used in the synthesis of new substances, the development of drugs, and many other fields.

2-Phenyl-3H-imidazolo [4,5-b] pyridine is an organic compound with many unique chemical properties.
In its structure, the core structure of imidazolo-pyridine endows the compound with specific electronic properties and spatial configuration. The imidazole ring contains two nitrogen atoms, and the pyridine ring has a conjugated system. The fusion of the two makes the molecular electron cloud unique, affecting its chemical activity and reactivity.
From the perspective of physical properties, the compound is mostly in a solid state, and the melting point is relatively high due to the existence of intermolecular forces. Its solubility varies according to the characteristics of the solvent. In polar organic solvents such as dimethyl sulfoxide, N, N-dimethylformamide, the solubility is better. Due to the interaction of molecular partial polarity with the solvent, it can help it disperse and dissolve. In non-polar solvents such as n-hexane and benzene, the solubility is poor. Because of the large difference between molecular polarity and non-polar solvents, it is difficult to interact and mix.
When it comes to chemical activity, the imidazole ring nitrogen atom is electron-rich and nucleophilic. It can participate in nucleophilic substitution reactions and react with electrophilic reagents such as halogenated hydrocarbons to introduce new substituents at the nitrogen atom to expand the structure The pyridine ring can also undergo electrophilic substitution reaction, although the activity is lower than that of the benzene ring, but under appropriate conditions, such as the presence of strong activating groups or the action of specific catalysts, substituents can be introduced at specific positions of the pyridine ring, such as nitrification and halogenation reactions. In addition, due to the existence of the conjugate system, the compound has certain photophysical properties, or can absorb specific wavelengths of light, undergo electron transitions, and exhibit fluorescent properties, which may have potential applications in optoelectronic devices, fluorescent probes and other fields.

The synthesis method of 2-phenyl-3H-imidazolo [4,5-b] pyridine has been around for a long time, and it has been evolving over time.
In the early days, the synthesis of this compound required many complicated steps and special raw materials. One method is to use pyridine derivatives as starting materials, first modify the pyridine ring and introduce specific substituents. This process requires fine regulation of reaction conditions, such as temperature, pH, etc., and a slight difference in the pool will affect the yield and purity.
At that time, the commonly used reaction was nucleophilic substitution reaction, which introduced suitable nucleophilic reagents on the pyridine ring to form key carbon-nitrogen or carbon-carbon bonds. After the cyclization reaction, the core skeleton of imidazolopyridine was constructed. However, this cyclization reaction requires a specific catalyst, and the structure of the reaction substrate is very strict.
With the improvement of chemical technology, new synthesis methods are gradually emerging. Modern synthesis methods pay more attention to atomic economy and step simplification. If the reaction path catalyzed by transition metals is used, and metals such as palladium and copper are used as catalysts, the construction of carbon-carbon and carbon-nitrogen bonds can be efficiently realized. Such reaction conditions are relatively mild and the universality of substrates is also good.
There is also a method of multi-component reaction synthesis, in which several simple raw materials are reacted in the same reaction system to construct a complex 2-phenyl-3H-imidazolo [4,5-b] pyridine structure in one step. This is due to the ingenious reaction design, which makes the orderly reaction between the raw materials and reduces the generation of intermediate steps and waste, which is the embodiment of the green chemistry concept.
However, regardless of the ancient methods and techniques, it is necessary to precisely control the reaction and improve the quality and yield of the product. The way of synthesis is like a craftsman's carving. It requires careful planning and patient practice to obtain a pure target product, which lays the foundation for subsequent research and application.

I look at your question, but I am inquiring about the price range of 2-phenyl-3H-imidazolo [4,5-b] pyridine in the market. However, the price of this product varies with quality, source, supply and demand, and it is difficult to determine.
If it comes from an ordinary workshop, the quality is average, and the supply in the market is quite sufficient, and the demand is not hot, the price may be slightly cheaper. The price per gram may be between tens and hundreds of dollars.
If it is a refined product, it comes from a famous workshop, and the quality is high, the impurities are rare, and there are many people in the market and the supply is not large, the price will be expensive. The price per gram, or to thousands of dollars, or even higher.
Furthermore, the amount purchased is also related to the price. If you buy in bulk, the merchant may give a discount to promote sales, and the price should be lower than the zero purchase.
The market conditions are fickle, and the price fluctuates accordingly. Or due to the rise and fall of raw materials, the improvement of processes, and changes in policies, the price may rise or fall. Therefore, in order to know the exact price of this item, you must consult the suppliers in detail to check the current price.