2-oxo-1,2-dihydropyridine-3-carboxylate

2-Oxo-1,2-dihydropyridine-3-carboxylic acid ester, which has a wide range of uses. In the field of medicine, it is an important intermediate in organic synthesis. Many pharmaceutical chemical structures contain this part. After chemical reaction modification, compounds with specific pharmacological activities can be obtained, such as some cardiovascular disease treatment drugs, which can help regulate the function of the cardiovascular system or lay the foundation for the development of new drugs.
In the field of materials science, it can participate in the preparation of functional materials. Due to its unique chemical structure and properties, it can endow materials with specific properties, such as improving the optical and electrical properties of materials, so that materials can show special application value in optoelectronic devices, sensors, etc., or improve material stability and durability.
In the field of organic synthesis chemistry, it is a key building block for the construction of complex organic molecules. With its structural characteristics, it undergoes a variety of chemical reactions with other organic reagents, such as cyclization, addition, etc., to synthesize organic compounds with diverse and complex structures, expand the chemical boundaries of organic synthesis, and provide the possibility for the creation of new compound molecules.
In short, 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters play an important role in many fields such as medicine, materials and organic synthesis due to their structural characteristics. With the deepening of scientific research, their application prospects will be broader.

The physical properties of 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters are described below.
This compound is mostly in a solid state at room temperature, but the specific properties may vary depending on the substituent. Its melting point is quite important. Different 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters have large differences in melting points. This is due to different molecular forces, such as hydrogen bonds, van der Waals forces, etc. When the intermolecular forces are strong, the melting point is higher; otherwise, it is lower. < Br >
Looking at its solubility, in organic solvents, such as ethanol, acetone, etc., it shows a certain solubility. Due to the existence of polar parts in its molecular structure, it interacts with the polarity of the organic solvent, resulting in solubility. In water, the solubility is relatively limited, because the polarity of water matches the polarity of the compound to the same extent as that of organic solvents.
Its density is also one of the physical properties. The size of the density is related to the weight of the molecule and the degree of close packing between molecules. If the molecular mass is large and the packing is close, the density is relatively large; otherwise, it is small.
Furthermore, the color state of the compound is usually almost colorless to light yellow, but it also changes due to impurities or specific groups in the structure.
In addition, its crystal structure is also an important physical property. The crystal structure is related to the arrangement of molecules in the lattice and affects many properties of compounds, such as hardness and optical properties.
In summary, the physical properties of 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters are influenced by many factors such as molecular structure and substituents, showing diverse characteristics.

To prepare 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters, the following ancient method can be used.
First take the pyridine as the group, and the nitrogen in the ring has a one-pair electron and is active. Under suitable reaction conditions, such as acyl halide or acid anhydride, under suitable reaction conditions, such as in an inert solvent, catalyzed by a mild base, the acyl group is electrophilically attacked at a specific position of the pyridine ring. The electron cloud density at the 2-position of the pyridine ring is relatively suitable, and it is vulnerable to acyl attack to form an intermediate product.
Then, the intermediate product is hydrogenated. Select a suitable hydrogenation reagent, such as metal hydride, and hydrogenate the 1,2-position double bond of the pyridine ring in a controlled reaction environment to obtain 1,2-dihydropyridine derivatives. This step requires attention to the reaction conditions to avoid structural changes caused by excessive hydrogenation.
Then carboxyl esterification of the resulting derivative is performed. Take the corresponding alcohol, and under acid catalysis, or the reaction of acid chloride and alcohol, the carboxyl group and alcohol are formed into esters. In acid catalysis, sulfuric acid or p-toluenesulfonic acid are commonly used to promote the esterification equilibrium to move in the direction of the product; the reaction of acid chloride and alcohol is relatively fast and the yield is high. After these steps, 2-oxo-1,2-dihydropyridine-3-carboxylic acid esters can be obtained. Each step requires precise control of conditions, such as temperature, time, and ratio of reactants, to obtain high-purity target products.

I don't know the price range of 2-oxo-1,2-dihydropyridine-3-carboxylate in the market. However, if you want to know the price of this product, you can find it in various ways.
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2-Oxo-1,2-dihydropyridine-3-carboxylate, this is an organic compound. However, it is difficult to specify its safety and toxicity due to the lack of literature.
Although it is difficult to find traces of this thing in ancient books such as "Tiangong Kaiwu", it is because there are many traditional processes and common things in ancient books, and such fine organic compounds cannot be prepared and recognized at that time.
Today's chemical research, the safety and toxicity assessment of compounds requires many experiments. Acute toxicity experiments can know its short-term damage to organisms; long-term toxicity experiments can know its chronic effects. Mutagenicity, teratogenicity and carcinogenesis experiments are related to the potential harm of heredity and body development.
To accurately determine the safety and toxicity of 2-oxo-1,2-dihydropyridine-3-carboxylate, when searching modern chemical literature, looking at professional experimental data and research results. If it is a newly synthesized compound, rigorous experiments and evaluations are required to clarify its effects on organisms and the environment, so as to ensure safe use.