2 Nitro 3 Difluoromethoxy Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Nitro-3-difluoromethoxy pyridine

    Specifications

    HS Code

    506232

    Chemical Formula C6H4F2N2O3
    Molecular Weight 192.104
    Appearance Typically a solid
    Melting Point Data may vary, needs specific determination
    Boiling Point Data may vary, needs specific determination
    Solubility In Water Low solubility
    Solubility In Organic Solvents Moderate solubility in some organic solvents
    Vapor Pressure Low vapor pressure
    Density Data may vary, needs specific determination
    Stability Stable under normal conditions but may react with strong oxidizing agents

    As an accredited 2-Nitro-3-difluoromethoxy pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 2-Nitro-3-difluoromethoxy pyridine prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 2-Nitro-3-difluoromethoxy pyridine in China?
    As a trusted 2-Nitro-3-difluoromethoxy pyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-Nitro-3-difluoromethoxy pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-nitro-3-difluoromethoxypyridine?
    2-% nitrile-3-diethylaminoethoxybenzene, this substance is widely used. In the field of medicine, it can be used as a key intermediate to help synthesize a variety of drugs. Due to its specific chemical structure, it can interact with many targets in organisms and affect the treatment process of diseases. For example, in the development of some cardiovascular disease drugs, by modifying and modifying its structure, the drug can more accurately act on the lesion site and improve the curative effect.
    In the field of materials science, it also has important value. It can be used to prepare polymer materials with unique functions. Because of its nitrile group and diethylaminoethoxy group, it gives the material good solubility, thermal stability and special optical and electrical properties. For example, when preparing high-performance liquid crystal materials, the introduction of this substance can optimize the arrangement of liquid crystal molecules, improve the display properties of the material, and make the display effect clearer and more stable.
    In the dye industry, 2-% nitrile-3-diethylaminoethoxy benzene is often used as a raw material for synthesizing new dyes. Due to its structure, the dye has a unique color and dyeing properties, which can dye fabrics with bright colors and high color fastness. The synthetic dye can be widely used in the textile printing and dyeing industry to meet the needs of different fabrics for dyeing.
    This compound plays an indispensable role in many important fields. With the continuous advancement of science and technology, its application prospects will become increasingly broad, and it is expected to give rise to more innovative achievements and applications.
    What are the synthesis methods of 2-nitro-3-difluoromethoxypyridine?
    To prepare 2-hydroxy-3-diethylaminoethoxybenzene, there are various methods.
    First, start with the corresponding phenols, and carry out nucleophilic substitution reaction with halogenated hydrocarbons containing diethylaminoethoxy groups under alkali catalysis. For bases, potassium carbonate and sodium hydroxide can be selected. In the reaction system, organic solvents also need to be adapted, such as acetone, acetonitrile, etc., to help them dissolve and promote the progress of the reaction. The temperature is controlled in a moderate range, and it is often heated to reflux to replace the hydroxyl group of the phenol with the halogen atom of the halogenated hydrocarbon to obtain the target product.
    Second, the principle of Williamson's synthesis method. First, the phenol is treated with a base, so that the phenolic hydroxyl group can become a phenoxy anion, and the activity is greatly increased. Later, when encountering the halogenated derivative of diethylaminoethanol, the phenoxy anion nucleophilic attacks the halogen atom ortho-carbon of the halogenated derivative, and the halogen ion leaves, and then forms an ether bond to obtain 2-hydroxy- 3-diethylaminoethoxy benzene. Among them, the strength of the base, the ratio of the reactants, the reaction temperature and time are all important factors, and need to be fine-tuned to achieve the best effect.
    Third, or through a multi-step reaction, a transformable group such as a halogen atom, a nitro group, etc. can be introduced before a specific position of the phenyl ring. After a series of transformations, the phenyl ring is modified Then by means of nucleophilic substitution, reduction and other reactions, hydroxyl and diethylaminoethoxy are gradually introduced. Although this route is complicated, under specific conditions, it may have advantages to avoid side reactions and improve yield and purity.
    Synthesis methods have their own advantages and disadvantages. Reaction conditions, ease of access to raw materials, cost considerations, purity and yield of the product are all the evidence for choice. It is necessary to study each method in detail, and it depends on the actual situation to form an efficient synthesis path.
    What are the physical properties of 2-nitro-3-difluoromethoxypyridine?
    The physical properties of 2-% hydroxy-3-diethylaminoethoxybenzophenone are as follows:
    This substance usually appears as a light yellow to yellow viscous liquid. Looking at its color, the color is light, but there is a faint yellowish color, like the first yellow leaves in autumn, revealing a soft color under the sun. Its texture is like a glue-like liquid, with an appropriate viscosity. It does not flow freely like water, but it is not thick and difficult to move. It is like a freshly boiled caramel, flowing slowly with a unique texture.
    Its melting point is low, just like the thin ice that melts rapidly under the warm sun in spring, usually around 48 ° C. At this temperature node, it quietly changes from solid to liquid, just like ice and snow turning into babbling water under the caress of the spring breeze. The boiling point is relatively high, about 166 ° C/1.33kPa, and it needs a higher temperature to boil, just like it needs to be tempered by a hot fire before it can be seen like a river rushing violently.
    It has good solubility and can be easily dissolved in organic solvents such as methanol, ethanol, and acetone like a smart fish into water. In these solvents, it seems to be integrated with the solvent, indistinguishable from each other, showing good mutual solubility. At the same time, it is also slightly soluble in water, just like a light feather. Although it cannot be fully integrated into the water, it can also maintain a subtle state of being away from the water above the water surface.
    It also has a certain degree of moisture absorption, just like a dry sponge placed in humid air, it will slowly absorb the moisture in the surrounding air, in order to balance the humidity relationship between itself and the external environment.
    What is the market prospect of 2-nitro-3-difluoromethoxypyridine?
    Today, there are 2-cyano-3-diethoxyaminobenzene, and its market prospects are related to many factors.
    Looking at its use, this substance is involved in the fields of medicine, pesticides and materials. In the pharmaceutical industry, or as a key intermediate for the creation of new drugs, because it contains special functional groups, it can participate in a variety of chemical reactions, help to build complex active molecular structures, and bring opportunities for the development of drugs to overcome difficult diseases. In the field of pesticides, pesticide products with high efficiency and low toxicity can be derived, which meet the current needs of green agriculture. If they can be successfully developed, they will be favored by the market. In the materials industry, special functional materials, such as photoelectric materials, can be chemically modified to meet the needs of emerging industries.
    In terms of its city, the current global chemical industry continues to evolve, and the demand for characteristic fine chemicals is growing. With in-depth scientific research and technological innovation, awareness of the properties and applications of 2-cyano-3-diethoxyaminobenzene is increasing. In addition, countries pay more attention to environmental protection and sustainable development. If the R & D and production process can conform to the concept of green chemistry, it will be able to dominate the market competition.
    However, there are also challenges. The chemical market is highly competitive, and similar or alternative products may exist. And R & D costs are high. From laboratory to industrial production, it is necessary to overcome problems such as engineering scale-up and quality control. Only with excellent technology, reasonable cost and stable quality can we gain a foothold in the market.
    In summary, if 2-cyano-3-diethoxyaminobenzene can effectively meet challenges, seize opportunities, expand applications in emerging fields, optimize production processes, reduce costs and increase efficiency, it will surely achieve great results in the future market, with promising prospects.
    What are the precautions for storing and transporting 2-nitro-3-difluoromethoxypyridine?
    2-% nitrile-3-diethoxyamino should be treated with caution during storage and transportation, and must not be slack in the slightest.
    When storing it, the first choice of environment. It needs to be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its active nature, heat can easily cause danger, and it is crucial to control temperature. Generally, it should be maintained in a specific low temperature range to prevent its chemical properties from changing. And it should be placed separately from oxidants, acids, bases and other substances, and must not be mixed. This is because it is prone to violent reactions with various chemicals, which may lead to unexpected disasters. Furthermore, the storage place should be equipped with suitable equipment for containing and handling leaks, in case of leakage, it can be properly disposed of in time and will not cause a disaster.
    As for transportation, it should not be taken lightly. Before transportation, be sure to ensure that the packaging is complete and tightly sealed to prevent its leakage and volatilization. Vehicles used for transportation must have good ventilation conditions, and must strictly abide by the relevant transportation regulations. Drive according to the designated route, and must not be changed at will to avoid passing through crowded areas or places with many fire sources. During transportation, escorts must always be vigilant and pay close attention to the condition of the goods, such as temperature, packaging damage, etc. In the event of an emergency, such as a damaged package causing it to leak, emergency measures should be taken immediately, evacuate the surrounding population, quickly report to the relevant departments, and properly handle the leakage according to the established emergency plan to prevent pollution of the environment and endanger the safety of everyone. In short, 2-% nitrile-3-diethoxylamino must follow strict specifications and requirements during storage and transportation to ensure safety.