2-(N-Methylamino)-3-hydroxymethylpyridine

2-%28N+-+Methylamino%29-3-hydroxymethylpyridine is 2- (N-methylamino) -3-hydroxymethylpyridine, which has a wide range of uses. In the field of medicine, it can be a key intermediate for the synthesis of many drugs. Because of its special chemical structure, it can interact with specific targets in organisms, which is of great significance for the development of drugs for the treatment of specific diseases. The creation of related drugs such as neurological diseases and cardiovascular diseases may be able to use it to build an infrastructure to help the construction of drug molecules to meet the needs of disease treatment.
In the field of materials science, it may participate in the synthesis of functional materials. With its active groups, it can play a unique role in the material synthesis process, such as regulating the optical and electrical properties of materials, providing the possibility for the preparation of new materials with special properties, and showing potential application value in the fields of optoelectronic materials, polymer materials, etc., helping to develop materials with better performance to meet the needs of different scenarios.
In organic synthetic chemistry, as a multifunctional reagent, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, condensation reactions, etc. Through these reactions, a series of organic compounds with diverse structures can be derived, expanding the synthesis path for organic synthetic chemists, enriching the organic compound library, promoting the continuous development of organic synthetic chemistry, and exploring more novel compounds and synthesis methods.

To prepare 2- (N-methylamino) -3-hydroxymethylpyridine, there are many methods, and the best ones can be obtained.
First, it can be started from a pyridine derivative. Introduce appropriate substituents at specific positions in the pyridine ring, such as using pyridine as a group, and use electrophilic substitution to connect specific carbon sites on the pyridine ring to groups containing suitable functional groups to lay the foundation for subsequent reactions. After multi-step conversion, such as under suitable conditions, specific reagents are used to promote the transformation of substituents, and methylamino and hydroxymethyl groups are gradually introduced. This process requires fine regulation of reaction conditions, and temperature, pH, and reaction time are all related to success or failure. If the temperature is too high, or cause side reactions to multiply and the product is impure; if the temperature is too low, the reaction will be slow and time-consuming.
Second, the pyridine ring can be constructed from compounds containing nitrogen and hydroxyl groups. Select raw materials containing nitrogen and hydroxyl groups with appropriate activity, and directly construct the pyridine ring through a series of reactions such as condensation and cyclization, and at the same time generate the key structure of the target molecule. This approach requires delicate design of the reaction route, considering the activity of the raw materials and the reaction sequence. For example, the difference in the activity of the raw materials affects the initial check point and process of the reaction. If the reaction is high in activity first, it can guide the reaction to the desired direction and avoid unnecessary side reactions.
Third, catalytic reaction is also a good strategy. Utilize high-efficiency catalysts to accelerate specific reaction steps. For example, transition metal catalysis can precisely promote the formation of carbon-nitrogen and carbon-oxygen bonds. However, the choice of catalyst is crucial, and the one with good activity and selectivity should be selected according to the reaction characteristics. If the activity is insufficient, the reaction is difficult to start; if the selectivity is poor, a complex mixture will be obtained, and separation and purification will be difficult.
Preparation of 2- (N-methylamino) -3-hydroxymethylpyridine requires detailed review of the advantages and disadvantages of each method. According to its own conditions, choose the best route and operate carefully to obtain a pure target product.

2-%28N+-+Methylamino%29-3-hydroxymethylpyridine, that is, 2 - (N - methylamino) - 3 - hydroxymethylpyridine, this physical property is particularly important, related to its performance in various reactions and applications.
Looking at its physical properties, under room temperature, it is mostly solid, colored or nearly white, if crystalline. Its melting point is quite fixed, because of the intermolecular force, it usually melts within a certain temperature range. This temperature range is especially critical for the material handling of experiments and production. It can be known that the node of its thermal transformation can be properly controlled at temperature.
Furthermore, its solubility is also an important item. In polar solvents, such as water and common alcoholic solvents, it exhibits a certain solubility. This is because there are both polar hydroxymethyl groups and nitrogen-containing methyl amino groups in the molecule, which can be dissolved in polar solvent molecules through hydrogen bonding, dipole-dipole interaction, etc. However, in non-polar solvents, the solubility is not good, which is related to molecular polarity. The force between non-polar solvents and the molecules of the substance is weak, making it difficult to disperse and dissolve.
And its volatility is relatively low. Due to the existence of hydrogen bonds and van der Waals forces between molecules, the molecules are bound in the system and are not easy to escape to the gas phase. This property can reduce its loss due to volatilization during storage and use, and also affect its reaction path and efficiency in some reactions that require gas phase participation.
As for the density, although there is no exact universal value, it is deduced according to the structure and the law of similar compounds. When its density is similar to that of common organic compounds, it is also a parameter that cannot be ignored in the design of separation, mixing and other processes. It is related to the space occupied by the material and the mass ratio, and has an impact on the specifications of the reaction vessel and the size of the conveying pipeline.
In summary, the physical properties such as melting point, solubility, volatility and density of 2 - (N-methylamino) -3-hydroxymethylpyridine are of critical significance in the fields of chemical research and chemical production.

2 - (N-methylamino) - 3 -hydroxymethylpyridine is one of the organic compounds. It has many unique chemical properties.
Looking at its structure, it contains a pyridine ring, which endows the compound with certain stability and aromaticity. The pyridine ring is a six-membered heterocycle with a conjugated system, which makes its chemical properties different from ordinary aliphatic compounds.
As far as the substituent is concerned, the presence of N-methylamino groups introduces the characteristics of amino groups. Amino groups have a certain alkalinity, because there are lone pairs of electrons on the nitrogen atom, which can bind protons. And the substitution of methyl groups affects the electron cloud density and steric resistance of amino groups, and then changes their alkalinity and reactivity.
Furthermore, the presence of 3-hydroxymethyl groups is also of great significance. Hydroxyl groups in hydroxymethyl groups can participate in various reactions, such as esterification reactions, and react with acids to form ester compounds. And hydroxyl groups are prone to form hydrogen bonds, which affect the physical properties of compounds, such as melting point, boiling point and solubility. Due to hydrogen bonding, the compound may have a certain solubility in water or some polar solvents.
At the same time, different groups in the compound interact with each other. For example, the conjugation effect of amino groups and pyridine rings affects the distribution of electron clouds on the pyridine ring, which in turn changes the activity and position selectivity of the substitution reaction on the ring. There are also electronic and spatial effects between hydroxymethyl groups and pyridine rings, which jointly determine the overall chemical properties and reaction behavior of the compound. It can be used as a key intermediate in the field of organic synthesis, participating in the construction of more complex organic molecular structures.

I have not heard the exact price of "2- (N-methylamino) -3-hydroxymethylpyridine" on the market. The price of this compound may vary depending on the purity, source, and purchase quantity.
If a small amount is purchased for experimental needs, and high purity is required, the price will be high. Due to the preparation of high-purity compounds, exquisite methods are often required, and multiple purifications are required, and the cost is high. For example, small packages sold by reagent companies, with purity of excellent grade purity, the price per gram may range from tens of yuan to hundreds of yuan.
If it is an industrial dosage and purchased in large quantities, the unit price may drop due to economies of scale. However, it also depends on market supply and demand. If the demand for this product is wide and the supply is tight, the price will be difficult to drop; conversely, if the supply exceeds the demand, the price may have room for downward adjustment.
Furthermore, different regions have different prices due to differences in transportation and taxes. Prosperous commercial ports, convenient logistics, or slightly lower prices; remote places, high transportation costs, or slightly higher prices.
There are different manufacturers, and the pricing is also different due to differences in production processes and cost control. Well-known large factories, with excellent quality and good after-sales service, or high prices; small factory products, although the price is low, the quality may be worried.
Therefore, if you want to know the exact price, you need to consult the chemical raw material supplier and compare its conditions in detail.