2 Methylthiopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-methylthiopyridine

    Specifications

    HS Code

    535731

    Chemical Formula C6H7NS
    Molar Mass 125.19 g/mol
    Appearance Liquid (usually)
    Odor Characteristic sulfur - containing odor
    Density Data varies, around 1.1 - 1.2 g/cm³
    Boiling Point 214 - 216 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, acetone
    Flash Point Data may vary, potentially around 80 - 90 °C

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    Frequently Asked Questions

    As a leading 2-methylthiopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-methylthiopyridine?
    2-Methylthiopyridine, or 2-methylthiopyridine, is a member of the family of organic compounds. This substance has unique physical properties and is widely used in the chemical field.
    Looking at its appearance, under room temperature and pressure, 2-methylthiopyridine is often colorless to light yellow liquid, like a clear oil, with a shimmer when flowing. Its smell is quite unique, pungent, and unforgettable. This smell is one of its most significant characteristics.
    When it comes to solubility, 2-methylthiopyridine exhibits good solubility in organic solvents, such as common ethanol, ether, chloroform, etc., just like fish entering water and easily fusing. However, its solubility in water is extremely limited, and the two are like incompatible enemies and difficult to fuse.
    The boiling point of 2-methyl thiopyridine is also one of its important physical properties. When the boiling point of 2-methyl thiopyridine is in a specific numerical range, it will transform from liquid to gaseous state at a certain temperature (the specific value depends on accurate measurement), and the physical state will change like a phoenix nirvana. This boiling point characteristic is of great significance for its separation and purification operations in chemical experiments and industrial production, so it can be effectively treated by distillation and other methods.
    In terms of density, 2-methyl thiopyridine also has a specific value. Compared with water, its density may be light or heavy (depending on the actual measurement). This density property plays a key role in operations such as delamination, providing an important basis for the control of related chemical processes.
    These physical properties of 2-methylthiopyridine, like its unique "chemical business card", not only help chemists understand its essence, but also lay a solid foundation for its application in many fields such as organic synthesis and drug development, making it an indispensable place in the vast world of chemistry.
    What are the chemical properties of 2-methylthiopyridine?
    2-Methylthiopyridine is also an organic compound. Its chemical properties are unique and have attracted much attention in the field of organic synthesis.
    First of all, its physical properties, 2-methylthiopyridine is a liquid with a special odor, which can be miscible with most organic solvents, but its solubility in water is quite limited. This property is closely related to its molecular structure. The presence of the pyridine ring gives it a certain polarity, while the introduction of methyl thio affects its solubility and volatility.
    In terms of chemical activity, the nitrogen atom of the pyridine ring has lone pairs of electrons, making it weakly basic and can react with acids to form corresponding salts. For example, in the case of strong acids such as hydrochloric acid, pyridine hydrochloride can be formed. At the same time, the π electron cloud structure of the pyridine ring makes 2-methylthiopyridine prone to electrophilic substitution. However, due to the high electronegativity of the nitrogen atom, the electron cloud is biased towards the nitrogen atom, so the electrophilic substitution activity on the pyridine ring is lower than that of the benzene ring, and the substitution position is mostly β-position.
    Furthermore, the methylthio group of 2-methylthiopyridine also participates in many chemical reactions. Sulfur atoms have lone pair electrons, which can be used as nucleophilic reagents to undergo nucleophilic substitution reactions with electrophilic reagents such as halogenated hydrocarbons, thereby realizing functional group transformation and structural modification of molecules.
    In addition, 2-methylthiopyridine also has unique performance in oxidation reactions. Suitable oxidants can oxidize sulfur atoms to form sulfoxides or sulfone derivatives. This process can regulate the polarity and chemical activity of compounds, providing more strategies and paths for organic synthesis.
    In conclusion, 2-methylthiopyridine has shown a wide range of application prospects in many fields such as medicinal chemistry and materials science due to its diverse chemical properties, providing rich materials and opportunities for the research and development of organic synthetic chemistry.
    What are the common synthetic methods of 2-methylthiopyridine?
    2-Methylthiopyridine is also an organic compound. The common synthesis methods have the following numbers.
    First, pyridine is used as a group to interact with methyl mercaptan. In this case, the nitrogen atom of the pyridine is nucleophilic, and the negative charge of the sulfur atom in the methyl mercaptan salt can undergo nucleophilic substitution with the carbon atom at a specific position on the pyridine ring. During the reaction, it is necessary to use appropriate solvents, such as dimethyl sulfoxide, under appropriate temperature and pressure. In this environment, the halogen atom (if any) on the pyridine ring can be replaced by methyl thiopyridine, so 2-methylthiopyridine is obtained. < Br >
    Second, through the conversion of sulfur-containing heterocycles. First prepare specific sulfur-containing heterocyclic compounds, such as some thiazole derivatives. Such compounds undergo a series of reactions such as rearrangement, ring opening and ring closing under specific reaction conditions, such as acid or base catalysis, in which sulfur atoms migrate and connect to pyridine rings, and methyl groups are introduced to obtain the final target product.
    Third, react with methyl mercaptan in an alkaline environment with 2-halogenated pyridine. The base can convert methyl mercaptan into methyl mercaptan negative ion. This negative ion has strong nucleophilicity and can attack the carbon atom connected by the halogen atom in 2-halopyridine, and the halogen atom leaves to form 2-methyl thiopyridine. During the reaction, suitable bases, such as potassium carbonate, sodium hydroxide, etc., need to be selected, and the temperature and time are controlled to obtain good yield.
    These synthesis methods have their own advantages and disadvantages. When implementing, they need to be weighed according to many factors such as the availability of raw materials, cost, and difficulty of reaction conditions.
    2-methylthiopyridine in what areas?
    2-Methylthiopyridine is useful in various fields. In the field of medicine, it can be used as a raw material for the synthesis of drugs. Because it has a specific chemical structure, it can interact with molecules in organisms and help create new drugs for the treatment of diseases. When developing antibacterial drugs, its structural characteristics can be used to enhance the affinity and activity of drugs to pathogens, so as to achieve better therapeutic effects.
    In the field of materials science, 2-methylthiopyridine is also quite useful. It can participate in the synthesis of special polymer materials, giving the materials unique properties. For example, when preparing materials with high selective adsorption properties for specific gases, the introduction of this compound can adjust the microstructure of the material, making it more adsorptive to specific gas molecules, and it is very useful in gas separation and purification.
    In the field of agriculture, it can be used to synthesize pesticides. With its chemical properties, efficient and low-toxicity pesticides can be prepared, which can not only effectively kill pests and bacteria, but also reduce the harm to the environment and the residual pollution of agricultural products, contributing to the green and sustainable development of agriculture.
    In the field of organic synthetic chemistry, 2-methylthiopyridine is often used as an important reagent and intermediate. Chemists can use it to participate in the synthesis of many complex organic compounds, and use its special reactivity to construct novel organic molecular structures, contributing to the development of organic synthetic chemistry.
    What is the market outlook for 2-methylthiopyridine?
    2-Methylthiopyridine is also an organic compound. It has considerable use in chemical, pharmaceutical and other fields, so the market prospect is quite promising.
    In the chemical industry, 2-methylthiopyridine is an important organic synthesis intermediate. Based on it, a variety of high-value fine chemicals can be prepared. For example, in the field of new materials research and development, through specific chemical reactions, with the special structure of 2-methylthiopyridine, polymer materials with unique properties can be synthesized. The demand for these materials in high-end fields such as electronics and aerospace is increasing, so the demand for 2-methylthiopyridine is also increasing.
    In the field of medicine, 2-methylthiopyridine also plays a key role. It is an indispensable raw material in the synthesis of many drugs. With the increasing aging of the global population, the scale of the pharmaceutical market continues to expand, and the demand for various drugs is increasing day by day. As an important intermediate in drug synthesis, 2-methylthiopyridine has also benefited from this trend, and the market demand is on the rise.
    Furthermore, with the progress of science and technology and the deepening of research and development, the application of 2-methylthiopyridine in emerging fields has gradually emerged. For example, driven by the concept of green chemistry and sustainable development, its potential value in new catalytic reactions and environmentally friendly product preparation is being gradually tapped. This undoubtedly opens up a broader market space for 2-methylthiopyridine.
    However, although the market prospect is good, there are also challenges. Optimization of production processes and cost control are urgent priorities. Efficient and environmentally friendly production technologies can make products stand out in market competition. In addition, the intensity of market competition cannot be underestimated, and competitors need to continuously improve product quality and service levels to compete for a place. Overall, the market for 2-methylthiopyridine has a bright future, but practitioners need to make unremitting efforts to meet various challenges in order to enjoy the dividends of market development.