2 Methylthio Oxazolo 4 5 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE

    Specifications

    HS Code

    936685

    Chemical Formula C7H6N2OS
    Molecular Weight 166.2
    Appearance Solid (usually)
    Odor Typical organic odor
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Density Data needed
    Pka Data needed
    Stability Stable under normal conditions
    Hazard Class Data needed

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    General Information
    Where to Buy 2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE in China?
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    Frequently Asked Questions

    As a leading 2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2- (METHYLTHIO) OXAZOLO [4,5-B] PYRIDINE
    2-%28METHYLTHIO%29OXAZOLO%5B4%2C5 - B% 5DPYRIDINE is 2 - (methylthio) oxazolo [4,5 - b] pyridine, which is an organic compound. Its physical properties are as follows:
    Viewed, it is usually a solid state. As for the exact color, it is either white or off-white, which varies depending on the preparation method and purity.
    Smells, or has a special odor. However, the specific description of this odor is difficult to be determined in the existing data.
    Measure its melting point, which is within a certain range. However, due to the test conditions and the purity of the sample, the exact value will fluctuate. In general, the melting point is one of the important characteristics of organic compounds, which can help in their identification and purity judgment.
    When it comes to solubility, it may have a certain solubility in common organic solvents, such as ethanol, dichloromethane, etc. This characteristic is very critical in organic synthesis and related chemical operations, because an appropriate solvent can be selected according to its solubility to facilitate the progress of the reaction, the separation and purification of the product.
    Its density is also a physical parameter. Although the exact value may vary depending on the measurement method, the relative density is of great significance to the design and understanding of processes involving liquid mixing and phase separation.
    Furthermore, the vapor pressure of 2- (methylthio) oxazolo [4,5 - b] pyridine is very low, which means that under normal temperature and pressure, its volatilization degree is limited.
    In summary, the physical properties of 2- (methylthio) oxazolo [4,5 - b] pyridine are all indispensable factors in the research, synthesis and application of organic chemistry in related fields. In-depth understanding of it can help to carry out related work more effectively.
    What are the chemical properties of 2- (METHYLTHIO) OXAZOLO [4,5-B] PYRIDINE
    2-%28METHYLTHIO%29OXAZOLO%5B4%2C5-B%5DPYRIDINE is 2 - (methylthio) oxazolo [4,5 - b] pyridine, which is an organic compound. Its chemical properties are particularly important and relate to many chemical and chemical things.
    In terms of its physical properties, it is mostly solid at room temperature, white or quasi-white, with a specific melting point and boiling point. The exact values of melting point and boiling point vary according to its purity and determination conditions. Its solubility in water is limited, but it can be soluble in some organic solvents, such as ethanol and acetone. Due to the "similar miscibility", the molecular structure of the compound has a suitable force with the organic solvent molecules, so it can be dissolved.
    As for the chemical properties, the oxazolopyridine ring and methylthio group in its structure give it unique reactivity. Oxazolopyridine ring has aromatic properties, so it has certain stability, but it can also participate in a variety of electrophilic substitution reactions. Due to the uneven distribution of electron clouds on the ring, specific positions can be attacked by electrophilic reagents. For example, under appropriate conditions, hydrogen atoms on the ring can be replaced by halogen atoms, nitro groups, etc. The sulfur atom in the methylthio group has lone pair electrons and can participate in the reaction as a nucleophilic center. For example, nucleophilic substitution occurs with halogenated hydrocarbons, forming new carbon-sulfur bonds and expanding molecular structures. In addition, the compound is quite sensitive to oxidation reactions, methionyl is easily oxidized to form sulfoxide or sulfone derivatives, which can be used as a substrate for oxidation reactions in organic synthesis to achieve functional group transformation and construct more complex molecules.
    2- (methionyl) oxazolo [4,5 - b] pyridine's chemical properties make it widely used in organic synthesis and medicinal chemistry, and can be used as a key intermediate for the creation of new bioactive compounds, providing an important foundation for new drug research and development and chemical production.
    2- (METHYLTHIO) OXAZOLO [4,5-B] What is the main use of PYRIDINE
    2-%28METHYLTHIO%29OXAZOLO%5B4%2C5-B%5DPYRIDINE is 2- (methylthio) oxazolo [4,5 - b] pyridine, which has a wide range of uses and is especially important in the field of medicine and chemical industry.
    First, it is a key intermediate in the process of drug development. The structure of Gein oxazolo-pyridine has unique biological activity and can be constructed by 2- (methylthio) oxazolo [4,5 - b] pyridine. Many studies have focused on exploring new compounds containing this structure, hoping that it has antibacterial, anti-inflammatory, anti-tumor and other effects. For example, some researchers have successfully obtained compounds with good anti-tumor activity by modifying this structure, which may pave a new way for the development of new anti-cancer drugs.
    Second, in the field of organic synthesis, 2- (methylthio) oxazolo [4,5 - b] pyridine is often used as a special reagent or structural unit. Due to its structural properties, it can participate in a variety of organic reactions, such as nucleophilic substitution, cyclization, etc., which help organic chemists construct complex and functional organic molecules, providing an effective path for the synthesis of new functional materials or fine chemicals.
    Third, in the field of materials science, it has also attracted attention. Due to specific electronic structures and chemical properties, rational design and modification may endow materials with special electrical and optical properties. For example, in the synthesis of optoelectronic materials, the introduction of this structure may improve the charge transport performance and luminous efficiency of materials, providing new options for the development of new optoelectronic materials.
    What are the synthesis methods of 2- (METHYLTHIO) OXAZOLO [4,5-B] PYRIDINE
    2-% (METHYLTHIO) OXAZOLO [4,5-B] PYRIDINE is 2- (methylthio) oxazolo [4,5-b] pyridine, and its synthesis method is as follows:
    To prepare 2- (methylthio) oxazolo [4,5-b] pyridine, you can start from the raw material containing the pyridine ring. First take the appropriate pyridine derivative and introduce the group that can be converted into the oxazolo-ring structure at the specific position of the pyridine ring. This step requires fine control of the reaction conditions to make the group localization accurate.
    Then, introduce the methylthio group. The method of introducing the methylthio group can use the reagent containing the methylthio group to react in a suitable catalyst and reaction medium. For example, methanethiol salts can be selected to undergo nucleophilic substitution reaction with suitable functional groups on pyridine derivatives under mild alkaline conditions, so that methylthio groups can be successfully integrated.
    When constructing the oxazole ring structure, it is often necessary to rely on condensation reactions. Compounds containing appropriate functional groups, such as condensable groups such as carbonyl and amino groups, are selected, and under the action of dehydrating agents or specific catalysts, they are cyclized and condensed in molecules to form the parent nuclear structure of oxazole [4,5-b] pyridine. During this period, the reaction temperature, reaction time and the ratio of reactants all have a great impact on the reaction process and product yield, and need to be carefully regulated.
    Or, from another idea, the oxazole ring is constructed first, and then it is connected to the pyridine ring. Through a specific reaction, the fragment containing the oxazole ring is combined with the pyridine derivative, and the methylthio group is introduced at the same time. This process also needs to strictly optimize the conditions of each step of the reaction to ensure the selectivity and high efficiency of the reaction, so as to obtain the target product 2- (methylthio) oxazolo [4,5 - b] pyridine.
    2- (METHYLTHIO) OXAZOLO [4,5-B] What is the price range of PYRIDINE in the market?
    There is a question today, what is the price range of 2 - (methyl thiogeneration) oxazolo [4,5 - B] pyridine in the market. However, the price of this compound is difficult to determine, because it varies due to various factors.
    First, the difficulty of preparing this compound is different. If the preparation method is complicated, requires multiple processes, rare raw materials, or harsh reaction conditions, the cost will be high, and the price will also be high. For example, in ancient alchemy, the process is cumbersome and the raw materials are rare, so the price of gold will be high.
    Second, market demand is also the key. If many industries compete for this compound, it is used in pharmaceutical research and development, material science, etc., the demand is strong and the supply is limited, and the price will rise. Just like the grain is cheap in a good year, the grain is expensive in a bad year, and the trend of supply and demand makes it so.
    Third, the quality grade affects the price. Those with high purity and few impurities are mostly used in high-end scientific research and pharmaceutical production, and the price is not cheap; those with low purity, or used in general industry, the price is slightly lower.
    Today in the market, the price may fluctuate from tens to hundreds of yuan per gram. In the fine chemical market, those with high quality can reach more than 200 yuan per gram; ordinary quality, or tens of yuan per gram. However, this is only a rough estimate, and the actual price often varies from time to time and changes with various factors in the market.