2 Methylimidazo 1 2 A Pyridine 3 Carboxylic Acid Ethyl Este
pyridine pyrrole pyrazine piperidine piperazine

2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl este

    Specifications

    HS Code

    696084

    Chemical Formula C11H12N2O2
    Appearance Solid (usually white to off - white powder)
    Boiling Point Estimated around 340 - 360°C under normal pressure
    Melting Point Typically in the range of 70 - 90°C
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Density Approximately 1.2 g/cm³
    Flash Point Estimated around 160 - 180°C
    Pka No specific common pKa data available for this molecule in standard conditions
    Odor May have a faint, characteristic odor

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    General Information
    Where to Buy 2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl este in China?
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    Frequently Asked Questions

    As a leading 2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl este supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-Methylimidazo [1,2-a] pyridine-3-carboxylic acid ethyl este
    2-Methylimidazolo [1,2-a] pyridine-3-carboxylate ethyl ester, this substance has a wide range of uses. In the field of medicine and chemical industry, it is often used as a key intermediate. Due to its unique structure, it can participate in a variety of chemical reactions, and after clever transformation, compounds with specific pharmacological activities can be obtained, which can be used in the development of new drugs. For example, using this as a starting material, through a series of organic synthesis steps, drugs with therapeutic effects on specific diseases may be prepared.
    In the field of materials science, it also has potential applications. In the preparation of some functional materials, its special chemical structure can be used to improve material properties. Such as introducing the substance during the synthesis of some polymer materials, or giving the material better stability and optical properties.
    Furthermore, in the study of organic synthetic chemistry, it is a favored research object. Chemists use the exploration of its reaction characteristics to expand new methods and paths of organic synthesis, and promote the development of organic chemistry. Its rich reaction check points and unique spatial structure provide many possibilities for synthetic chemistry, motivating researchers to continuously explore new reactions and new synthesis strategies.
    What are the physical properties of 2-Methylimidazo [1,2-a] pyridine-3-carboxylic acid ethyl este
    2-Methylimidazolo [1,2-a] pyridine-3-carboxylate ethyl ester, the physical properties of this substance are as follows.
    Looking at its properties, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This is because the atoms in the molecular structure interact, resulting in the orderly arrangement of molecules, showing such an appearance.
    When it comes to the melting point, it is usually within a specific range. The intermolecular forces and crystal structure of this compound determine the melting point. During the heating process, the molecule obtains enough energy to overcome the lattice energy, resulting in a phase transition.
    As for solubility, it shows a certain solubility in organic solvents such as ethanol and dichloromethane. This is because the compound molecule and the organic solvent molecule can form interactions such as hydrogen bonds, van der Waals forces, etc., so that it can be dispersed in the solvent. However, in water, the solubility is relatively limited, because its molecular structure is not highly hydrophilic, and the interaction between water molecules and compound molecules is weak, making it difficult to disperse a large amount in the aqueous phase.
    In addition, its density also has a specific value, which reflects the mass of the substance per unit volume, and is related to the relative mass of the molecule and the way the molecule is deposited. Its stability is acceptable under normal conditions, but in case of extreme environments such as strong acids, strong bases or high temperatures, its molecular structure may change, causing chemical properties to change.
    In summary, the physical properties of ethyl 2-methylimidazolo [1,2-a] pyridine-3-carboxylate are determined by its molecular structure, which plays a key role in various chemical processes and practical applications.
    What is the chemical synthesis method of 2-Methylimidazo [1,2-a] pyridine-3-carboxylic acid ethyl este
    The synthesis of 2-methylimidazolo [1,2-a] pyridine-3-carboxylate ethyl ester is an important research direction in the field of organic synthesis. Its synthesis path often requires a multi-step reaction, the steps are as follows:
    The first step is to select suitable starting materials, such as specific pyridine derivatives and imidazole derivatives as starting materials. The selection of pyridine derivatives requires specific substituents for subsequent reactions. This starting material is carefully selected, because the structural characteristics of the starting material are crucial to the formation of the product.
    The second step is to carry out the key reaction step. The condensation reaction is often the beginning, and under suitable reaction conditions, the pyridine derivative and the imidazole derivative are condensed with each other. This condensation reaction requires precise control of the reaction temperature, reaction time and the proportion of reactants. Generally speaking, the reaction temperature is set to a moderate range, such as between 50 and 80 ° C, and the reaction time lasts for several hours to ensure that the reaction is fully carried out. The ratio of reactants also needs to be strictly controlled to ensure the accurate ratio of the two, so as to promote the reaction towards the formation of the target product.
    Furthermore, in order to make the product have the desired ethyl carboxylate structure, an esterification reaction needs to be carried out. In this step, select an appropriate esterification reagent, such as ethanol and a suitable catalyst. The catalyst can be selected from concentrated sulfuric acid, etc., to promote the esterification reaction at a specific temperature and reaction environment. The reaction temperature is usually controlled at 70-100 ° C, and the reaction temperature is continuously stirred to allow the react
    During the reaction process, the reaction situation must be closely monitored. The progress of the reaction can be tracked in real time by thin layer chromatography (TLC), and the consumption of raw materials and the formation of products can be observed. When the reaction reaches the expected level, the product is separated and purified. Column chromatography or recrystallization is often used to obtain high-purity 2-methylimidazo [1,2-a] pyridine-3-carboxylate products. In column chromatography, separation is achieved according to the difference in the partition coefficient between the product and the impurity in the stationary phase and the mobile phase; recrystallization method uses the different solubilities of the product and the impurity in a specific solvent to achieve the purpose of purification through multiple crystallization operations. In this way, through a series of carefully designed and strictly controlled reaction steps, the target product can be obtained.
    2-Methylimidazo [1,2-a] pyridine-3-carboxylic acid ethyl este What are the precautions in storage and transportation
    Ethyl 2-methylimidazolo [1,2-a] pyridine-3-carboxylate is an organic compound. When storing and transporting, the following numbers should be paid attention to:
    First, when storing, place in a cool, dry and well-ventilated place. This is because the compound may be quite sensitive to humidity and temperature, and high temperature or high humidity environment may cause it to deteriorate. If the moisture is too heavy, or the reaction such as hydrolysis is initiated, the purity and quality of the compound will be damaged; if the temperature is too high, it may accelerate the chemical reaction rate and reduce its stability.
    Second, keep away from fire and heat sources. Because of its flammability, in case of open flame, hot topic or cause combustion danger, it threatens storage and transportation safety.
    Third, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. Due to its chemical properties, contact with these substances may trigger violent chemical reactions, or cause serious accidents such as explosion and leakage. For example, contact with strong acids and alkalis, or hydrolysis of ester groups, changing the structure and properties of compounds.
    Fourth, the storage place should be equipped with suitable materials to contain leaks. Once a leak occurs, it can be dealt with in a timely and effective manner to prevent the spread of pollution and reduce the harm to the environment and personal safety.
    Fifth, during transportation, ensure that the container does not leak, collapse, fall, or damage. Compounds leak due to bumps, collisions, or rupture of the container.
    Sixth, when transporting, you need to follow the specified route and do not stop in residential areas and densely populated areas. This can reduce the harm to many people in the event of an accident and ensure public safety.
    What is the market price range for 2-Methylimidazo [1,2-a] pyridine-3-carboxylic acid ethyl este
    There is a question today, what is the market price range of 2 - Methylimidazo [1,2 - a] pyridine - 3 - carboxylic acid ethyl este. This is a question in the field of fine chemicals, and its price is affected by multiple factors.
    First, the difficulty of the production process is related to the cost, which in turn affects the price. If the process is complicated, special equipment and technology are required, the cost will rise, and the price will be high. Second, purity is also the key. High purity is mostly used in high-demand fields such as pharmaceutical research and development, which is difficult to prepare and expensive; low purity is used in general industry, and the price is slightly lower. Third, the market supply and demand situation has a significant impact. With strong demand and limited supply, prices will rise; on the contrary, if supply exceeds demand, prices will fall.
    Check the past market transaction records, and the price of this chemical fluctuates greatly. In the fine chemical raw material trading market, the price per gram may be in the range of hundreds of yuan for those with higher purity and high quality; if the purity is slightly lower, for ordinary industrial synthesis, the price per gram may drop to tens of yuan. However, this is only a rough range, and the specific price depends on the current market conditions, buyer-seller negotiation, and transaction quantity. In short, its market price varies due to many factors, and it is difficult to have a fixed number.