2 Methylamino 3 Nitro 6 Chloropyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Methylamino-3-nitro-6-chloropyridine

    Specifications

    HS Code

    653852

    Chemical Formula C6H6ClN3O2
    Molecular Weight 187.58
    Appearance Solid (usually a powder or crystalline solid)
    Color May vary, often off - white to yellowish
    Odor Typically has a characteristic, potentially pungent odor
    Melting Point Specific value would require lab determination
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like acetone, dichloromethane
    Pka No common pKa value readily available without experimental determination
    Stability Can be stable under normal conditions but may decompose on exposure to heat, light or strong acids/bases
    Hazard Class Potentially hazardous, may be toxic if ingested, inhaled or absorbed through skin

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    General Information
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    Frequently Asked Questions

    As a leading 2-Methylamino-3-nitro-6-chloropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Methylamino-3-nitro-6-chloropyridine?
    2-Methylamino-3-nitro-6-chloropyridine has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help create new drugs. The unique structure of Geinpyridine compounds can interact with many targets in organisms. By modifying the structure of 2-methylamino-3-nitro-6-chloropyridine, specific drugs for specific diseases, such as tumors and cardiovascular diseases, can be developed.
    In the field of pesticides, it also has important functions. As a raw material, a variety of high-efficiency pesticides can be synthesized. The pesticides based on it are highly selective and toxic to pests, and environmentally friendly. Due to its specific chemical structure, it can precisely act on the specific physiological processes of pests, such as interfering with the nervous system of pests or inhibiting their growth and development, so as to achieve the purpose of efficient pest control, while reducing the impact on the environment and non-target organisms.
    In the field of materials science, 2-methylamino-3-nitro-6-chloropyridine also shows potential value. Or can participate in the preparation of special functional materials, such as materials with specific optical and electrical properties. Due to its nitrogen, chlorine and other elements and specific functional groups, during the material synthesis process, the material may be endowed with a unique electronic structure and spatial configuration, which in turn makes the material exhibit special properties such as fluorescence and conductivity, opening up new paths for the research and development of new functional materials.
    What are the physical properties of 2-Methylamino-3-nitro-6-chloropyridine?
    2-Methylamino-3-nitro-6-chloropyridine, this is an organic compound. Its physical properties are quite important and are related to applications in many fields.
    Looking at its properties, it is mostly in solid form at room temperature. This state makes it necessary to follow specific rules during storage and transportation to maintain stability. As for the color, it is often light yellow to yellow, and the depth of color may vary due to differences in purity.
    Melting point is one of the key physical properties. After many experiments, the melting point of 2-methylamino-3-nitro-6-chloropyridine is within a certain range. The melting point can help determine the purity of the substance. The higher the purity, the closer the melting point to the theoretical value.
    Solubility cannot be ignored either. In common organic solvents, their solubility varies. In some organic solvents, such as methanol and ethanol, there is a certain solubility. This property facilitates its chemical synthesis and purification steps. It can be used to select suitable solvents to achieve the purpose of separation and purification. However, in water, the solubility is relatively low, because the molecular structure of the compound has fewer hydrophilic groups and a larger proportion of hydrophobic groups.
    In addition, 2-methylamino-3-nitro-6-chloropyridine has a certain density. Density data is of great significance to chemical production. It is related to the calculation of reactor volume, material ratio and other links to ensure the accuracy of the production process.
    Understanding the physical properties of this compound not only helps chemical researchers design synthesis routes and optimize reaction conditions, but also lays the foundation for its application in materials science, medicinal chemistry and other fields. By mastering its physical properties, it can better control its behavior in various systems and achieve the expected functions and effects.
    What is 2-Methylamino-3-nitro-6-chloropyridine synthesis method?
    The synthesis of 2-methylamino-3-nitro-6-chloropyridine is a crucial issue in the field of organic synthesis. The synthesis route is a conventional approach of multi-step chemical synthesis, which varies according to different starting materials and reaction conditions.
    One of the common methods is to use a specific pyridine derivative as the starting material. If a pyridine compound is taken first, its structure needs to have a check point for subsequent reaction modification. In a suitable reaction vessel, add the pyridine substrate and dissolve it in a suitable organic solvent to create a homogeneous reaction environment. Then, under strictly controlled temperature and stirring conditions, add the methylamino-containing reagent dropwise. The choice of this reagent needs to consider its reactivity and selectivity to ensure that the methyl amino group is accurately introduced into the target check point. During the reaction, the control of temperature is extremely critical, too high or too low can cause side reactions to occur or the reaction rate is too slow.
    After the successful introduction of methyl amino group, transfer to the nitroization step. Here, select a suitable nitrifying reagent, such as the mixed acid system of nitric acid and sulfuric acid. At low temperature and with sufficient stirring, slowly add the mixed acid to the reaction system. Due to the strong exothermic nature of the nitrification reaction, if the operation is not careful, it is easy to cause the reaction to go out of control. This step aims to introduce nitro groups at specific positions in the pyridine ring to achieve part of the structure of the target molecule.
    Finally, carry out the chlorination reaction. Select a suitable chlorination reagent, such as a chlorine-containing halogenating agent. In the presence of an appropriate catalyst, the chlorination reagent is fully reacted with the modified pyridine derivative, and chlorine atoms are introduced at the designated position to successfully synthesize 2-methylamino-3-nitro-6-chloropyridine. During the whole synthesis process, after each step of the reaction, the product needs to be separated and purified by means such as column chromatography and recrystallization to ensure the purity of the product in each step and lay a good foundation for the subsequent reaction. In this way, the target product 2-methylamino-3-nitro-6-chloropyridine can be obtained through the carefully designed and operated reaction of multiple steps.
    What are the precautions in storage and transportation of 2-Methylamino-3-nitro-6-chloropyridine?
    2-Methylamino-3-nitro-6-chloropyridine is a chemical substance. When storing and transporting, many matters need to be paid attention to.
    First words storage. This substance needs to be placed in a cool, dry and well ventilated place. Because of its sensitivity to heat, if it is exposed to high temperature environment, it may cause chemical changes and even cause dangerous reactions. And moisture is also a big enemy. Humid environment may affect the purity and stability of the substance. Furthermore, it should be stored separately from oxidizing agents, acids, bases and other substances. Because of its active chemical properties, contact with the above substances, or react violently, it can be stored in isolation to ensure safety. The storage area also needs to be equipped with suitable containment materials in case of leakage.
    Times and transportation. Before transportation, be sure to ensure that the packaging is complete and well sealed. This can prevent material leakage and avoid harm to the transporter and the surrounding environment. During transportation, keep away from fire and heat sources. Because it is flammable or may react with heat, it is close to the fire source heat source, which is prone to danger. Transport vehicles should also be equipped with corresponding fire equipment and leakage emergency treatment equipment to deal with emergencies. At the same time, transport personnel need professional training, familiar with the characteristics of the substance and emergency treatment methods, in order to ensure safety during transportation.
    2-Methylamino-3-nitro-6-chloropyridine impact on the environment and human health
    2-Methylamino-3-nitro-6-chloropyridine is a chemical substance. The impact on the environment and human health must be investigated in detail.
    As far as the environment is concerned, if this chemical substance escapes into the nature, it may have multiple effects. It may accumulate in the soil, causing changes in soil properties, or hindering plant roots from taking up nutrients and water, thereby affecting plant growth. Inflow into water bodies, or cause water quality deterioration, endangering aquatic organisms. Or change the chemical composition of water bodies, affecting the living environment of aquatic organisms, causing their reproduction and growth to be blocked, and even causing some species to become extinct, destroying the balance of aquatic ecology.
    As for personal health, its potential harm should not be underestimated. It enters the human body through breathing, skin contact or ingestion, or causes a series of health problems. Or irritate the respiratory tract, cause cough, asthma and other diseases; contact with the skin, or cause skin allergies, redness, swelling, itching. If ingested by mistake, or damage the digestive system, causing nausea, vomiting, abdominal pain, etc. Long-term exposure to this substance may be potentially carcinogenic, affecting the genes of the human body, causing cell mutations, and increasing the risk of cancer. And may damage the nervous system, affect nerve conduction, make people slow to respond, memory loss, etc.
    Therefore, the use and disposal of 2-methylamino-3-nitro-6-chloropyridine should be treated with caution, and proper protection and treatment methods should be adopted to reduce its harm to the environment and human health.