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What are the main uses of 2-Methylamino-3-amino-6-methoxypyridine?
2-Methylamino-3-amino-6-methoxypyridine, which has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate in organic synthesis. It can be skillfully converted into compounds with more complex structures through specific chemical reactions, which can be used to create a variety of new drugs. For example, in the development of antimalarial drugs, it plays an indispensable role in helping to construct molecular structures with specific pharmacological activities to achieve anti-malaria parasite effects.
In the field of pesticide chemistry, it also plays an important role. It can be used as a starting material for the synthesis of highly efficient and low-toxicity pesticides. Through chemical modification and reaction, pesticide ingredients that can effectively kill pests and protect crops are generated. Due to its structural characteristics, the synthesized pesticides may have good bioactivity and environmental compatibility, which is in line with the current needs of green agriculture development.
Furthermore, in the field of materials science, it has also emerged. It can participate in the preparation of functional materials, such as some sensor materials with the ability to identify specific substances. With its unique molecular structure and properties, it interacts specifically with the target substance, and then realizes the detection and identification of substances, which has potential application value in environmental monitoring, food safety testing, etc.
In conclusion, 2-methylamino-3-amino-6-methoxypyridine has shown extraordinary uses in many fields such as medicine, pesticides and materials, and has contributed significantly to the development of various fields.
What are 2-Methylamino-3-amino-6-methoxypyridine synthesis methods?
To prepare 2-methylamino-3-amino-6-methoxypyridine, there are three methods.
First, start with 6-methoxy-3-nitropyridine. Let it react with methylamine to obtain 6-methoxy-3- (methylamino) nitropyridine. This step requires temperature control in a suitable range, and the choice of solvent is very important. Alcohol solvents are commonly used. After hydrogenation with suitable reducing agents, such as iron powder-hydrochloric acid system or palladium carbon, the nitro group is also an amino group to obtain the target. This step is still simple, but when the nitro group is reduced or impurities are generated, fine separation is required.
Second, starting from 2-chloro-6-methoxypyridine. First react with methylamine to obtain 2-methylamino-6-methoxypyridine. Then use a suitable amination reagent, such as liquid ammonia and a catalyst, to introduce the amino group at the 3rd position under high temperature and pressure. The amination conditions are severe and the equipment requirements are quite high, so the purity of the product is good.
Third, use 2,3-dichloro-6-methoxypyridine as a group. React with methylamine first, so that one chloride is replaced by a methylamino group. Second, use liquid ammonia and a suitable catalyst, so that another chlorine is replaced by an amino group. The raw materials are easy to buy, but the reaction conditions may be difficult to control. The selectivity of the second substitution product needs to be studied in detail. Each method has its own advantages and disadvantages. In actual preparation, the appropriate method should be carefully selected according to the availability of raw materials, the condition of equipment and the purity of the product.
What are the physical properties of 2-Methylamino-3-amino-6-methoxypyridine?
2-Methylamino-3-amino-6-methoxypyridine is one of the organic compounds. Its physical properties are quite important and have many applications in chemical and scientific research fields.
This compound is mostly solid at room temperature, and its appearance is usually white to off-white crystalline powder, like a fine powder, with uniform texture. Its melting point is also a key physical property. It usually melts within a specific temperature range. This temperature range is of great significance for its identification and purity determination.
Furthermore, solubility is also a significant physical property. In common organic solvents, such as ethanol, dichloromethane, etc., it may have certain solubility. In ethanol, it may be partially soluble to form a uniform solution, but its solubility in water may be poor, and it is mostly insoluble or slightly soluble.
In addition, the density of the compound is also a specific value. Although there is no exact data to specify, this physical quantity is of guiding value in chemical process design, such as material ratio, reaction vessel selection, etc.
Its stability in air also needs to be considered. Although there is no exact data to explain its stability geometry, organic compounds may react with oxygen and moisture in the air, so they may need to be properly stored to prevent deterioration.
In summary, the physical properties of 2-methylamino-3-amino-6-methoxypyridine, such as appearance, melting point, solubility, density and stability, etc., play an important role in scientific research and chemical production. In-depth investigation of it will help to better apply this compound.
What are the chemical properties of 2-Methylamino-3-amino-6-methoxypyridine?
2-Methylamino-3-amino-6-methoxypyridine, this is an organic compound with specific chemical properties.
Its appearance may be white to light yellow crystalline powder, because compounds of the same structure are mostly in this appearance. In terms of solubility, because it contains polar groups or is slightly soluble in water, it can be better soluble in organic solvents such as methanol, ethanol, and dichloromethane, just like many pyridine compounds containing amino and methoxy groups.
When it comes to chemical activity, amino groups are active groups and can participate in a variety of reactions. First, it is easy to react with acids to form salts, and interact with hydrochloric acid, sulfuric acid, etc., to form corresponding salts, which is a typical property of amino groups. Second, under appropriate conditions, nucleophilic substitution reactions can be carried out, because there are lone pairs of electrons on the nitrogen atom, which is nucleophilic and can react with halogenated hydrocarbons and other electrophilic reagents to generate new nitrogen-containing derivatives. Third, although the methoxy group is relatively stable, some reactions may occur under strong acidic or alkaline conditions, such as in strong acids, or the reaction of ether bond breaking.
In terms of stability, under normal storage conditions, this compound may be relatively stable. However, it is necessary to avoid contact with strong oxidizing agents and strong acids and bases to prevent violent reactions from occurring, resulting in structural changes or decomposition. The groups of 2-methylamino-3-amino-6-methoxypyridine exhibit specific physical and chemical properties and may have important uses in organic synthesis and other fields.
What is the price range of 2-Methylamino-3-amino-6-methoxypyridine in the market?
I look at this question, but I am inquiring about the price range of 2-methylamino-3-amino-6-methoxypyridine in the market. However, the price of this chemical often varies due to many factors.
First, quality is important. For high purity, the price will be high; the purity is slightly inferior, and the price may drop. If it is a high-purity product of scientific research grade, the impurity content is strictly controlled, and its price should be higher than that of industrial grade, which requires slightly lower purity.
Second, the supply and demand situation also has a great impact. If the market demand for this product is strong and the supply is limited, the price will rise; on the contrary, if the supply exceeds the demand, the price may decline.
Third, the origin of the source is related to the price. Different origins, due to differences in production costs, transportation conditions, etc., lead to different prices. Distant origins, with transportation costs, the price may be higher.
Fourth, the purchase volume also affects the price. If you buy in large quantities, merchants may give discounts, with small profits but quick turnover; if you buy in small quantities, the unit price is often high.
It is difficult to determine the exact price range after checking the market records of the past. Today, the price of this chemical may fluctuate frequently. For accurate prices, you can consult chemical product suppliers, trading platforms, or go to the chemical market survey in person to get the current real price range.