2 Methyl 5 Bromopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Methyl-5-Bromopyridine

    Specifications

    HS Code

    872618

    Chemical Formula C6H6BrN
    Molar Mass 172.02 g/mol
    Appearance Solid (usually white to off - white)
    Boiling Point 212 - 214 °C
    Melting Point 39 - 41 °C
    Density 1.55 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point 82 °C
    Pka 3.76
    Odor Characteristic, unpleasant

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    General Information
    Where to Buy 2-Methyl-5-Bromopyridine in China?
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    Frequently Asked Questions

    As a leading 2-Methyl-5-Bromopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-methyl-5-bromopyridine?
    2-% methyl-5-hydroxypyridine is an organic compound. Its physical properties are quite unique and closely related to many applications.
    In terms of appearance, this compound is mostly white to pale yellow crystalline powder at room temperature, just like fine sand, with uniform texture. Its color is pure, like the first snow in winter, showing a sense of purity.
    Looking at its melting point, it is about 145-148 ° C. Just like ice melts when it is warm, when the temperature rises to a specific range, 2-% methyl-5-hydroxypyridine quietly converts from solid to liquid. This melting point characteristic plays a crucial role in its purification and identification process, like a precise ruler, helping chemists determine its purity.
    As for solubility, 2-% methyl-5-hydroxypyridine is soluble in water, just like salt melted into soup, quietly disappearing, but giving water a different chemical property. At the same time, it also has good solubility in common organic solvents such as ethanol and acetone. This property makes it like a duck to water in organic synthesis reactions, freely shuttling through different solvent environments, setting up an ideal stage for various chemical reactions.
    Its density is about 1.26 g/cm ³, which is like a code for measuring the relationship between weight and volume of an object. This density value gives us a clear basis when considering its storage and transportation, and knows how to properly place it to ensure its safety.
    Furthermore, 2-% methyl-5-hydroxypyridine also has certain sublimation properties. Under certain conditions, it can be directly converted from a solid state to a gaseous state like a cloud, which is very useful in some separation and purification processes. It is like a mysterious dancer who performs unique variations on the stage of chemistry.
    What are the common synthesis methods of 2-methyl-5-bromopyridine?
    The common synthesis methods of 2-% methyl-5-furanyl include the following:
    One is a method using furan as the starting material. Furan can be reacted with halomethane under specific conditions. This reaction needs to be carried out under the action of suitable catalysts, such as some metal salt catalysts. Through this reaction, the methyl group of halomethane can replace the hydrogen atom at a specific position on the furan ring, thereby introducing methyl groups. Subsequently, after a series of functional group conversion reactions, such as oxidation, reduction, substitution, etc., the desired furanyl structure is gradually constructed at a suitable position. The raw materials for this method are easily available, but the reaction steps are slightly complicated, and the reaction conditions of each step need to be carefully controlled to ensure that the reaction proceeds in the desired direction.
    The second is the strategy of using organometallic reagents. First prepare organometallic reagents containing furan groups, such as lithium furan or magnesium furan. Then, the organometallic reagent reacts with electrophilic reagents containing methyl groups, such as methyl halide or methyl sulfonate. Through such nucleophilic substitution reactions, methyl groups can be introduced into furan-specific sites. This method has high reactivity and good selectivity, but organometallic reagents require strict reaction conditions and need to be operated in an anhydrous and oxygen-free environment to avoid reagent failure.
    Furthermore, it can be synthesized by means of cyclization reaction. Select a suitable chain compound, whose molecular structure needs to contain both functional groups that can construct furan rings and methyl introduction check points. Under suitable reaction conditions, such as in a specific catalyst, temperature and solvent environment, the chain compound undergoes intra-molecular cyclization reaction, and the construction of methyl and furan groups is completed at the same time. This method is relatively compact and has high atomic economy, but it is quite challenging to find suitable starting chain compounds and optimize cyclization reaction conditions.
    In addition, there are conversion methods using heterocyclic compounds as raw materials. Heterocyclic compounds with similar structures are selected and gradually converted into 2-methyl-5-furan groups through a series of ring opening, ring closing and substitution reactions. This method requires in-depth understanding of heterocyclic chemistry and rational design of reaction routes in order to achieve the synthesis of the target product efficiently.
    What fields are 2-methyl-5-bromopyridine used in?
    2-% methyl-5-nitropyridine, which is used in many fields such as medicine, pesticides, and materials.
    In the field of medicine, it is a key organic synthesis intermediate. The construction of many drug molecules requires this as the starting material, and various chemical reaction steps can be used to produce drugs with specific biological activities. For example, in the synthesis of some antibacterial drugs, 2-methyl-5-nitropyridine can participate in the construction of the core structure of drug molecules. By modifying and modifying its structure, it can enhance the inhibition and killing ability of drugs against specific bacteria, and escort human health.
    In the field of pesticides, 2-methyl-5-nitropyridine also plays an important role. On this basis, a variety of high-efficiency pesticides can be synthesized, and some pesticides cannot be created without it. With its unique chemical structure, the synthesized insecticides can precisely act on specific physiological targets of pests and interfere with the normal physiological metabolism of pests, so as to achieve the purpose of efficient insecticides, protect crops from insect infestation, and help agricultural harvests.
    The field of materials science is also a place for 2-methyl-5-nitropyridine. When synthesizing certain functional materials, it can be introduced into polymers as a structural unit. For example, in the process of preparing polymer materials with special optoelectronic properties, the addition of 2-methyl-5-nitropyridine can regulate the electron cloud distribution of the material, thereby improving the optical absorption and emission characteristics of the material, so that the material can be used in optoelectronic devices, such as organic Light Emitting Diode (OLED). This shows potential application value and promotes the continuous progress and development of materials science.
    What is the approximate market price of 2-methyl-5-bromopyridine?
    The price of 2-methyl-5-nitropyridine often varies for various reasons, making it difficult to determine the exact number. However, according to past market conditions and industry reports, its price probably has a range to be found.
    In today's world, the price of chemical products is mostly determined by the abundance of raw materials, the simplicity of the process, and the urgency of supply and demand. 2-methyl-5-nitropyridine, its preparation requires exquisite methods, and the raw materials may be rare. If the raw materials are sufficient and the process is smooth, the supply in the city is safe, and the price may be slightly cheaper. On the contrary, if the raw materials are scarce, or the preparation process is blocked, the output is sparse, and there are many people who need it, the price will be high.
    Looking at the era of past transactions, in the state of balance between supply and demand, the price of 2-methyl-5-nitropyridine per kilogram is about a few hundred yuan. However, the market situation changes, and there have been sudden shortages of raw materials, causing prices to soar to more than 1,000 yuan; there are also large increases in production capacity, oversupply, and prices fall to a lower position.
    Therefore, in order to know the exact price, when consulting chemical companies, real-time supply and demand, knowing the situation of raw materials, and changes in processes, the price can be obtained. Although it is difficult to describe the specific geometry in a single word, in normal times, the price per kilogram is several hundred yuan, or it is a common state.
    What are the storage conditions for 2-methyl-5-bromopyridine?
    The storage conditions of 2-% methyl-5-furanaldehyde need to be paid attention to in many aspects. This compound is more active and sensitive to environmental factors.
    First, temperature is very important. It should be stored in a cool place to avoid the disturbance of high temperature. High temperature can easily cause its volatilization to intensify, or cause chemical reactions to cause its deterioration. Generally speaking, it is appropriate to maintain the temperature at 2 ° C - 8 ° C. This temperature range can effectively slow down its physical and chemical change rate and ensure its stability.
    Second, light is also a key factor. 2-methyl-5-furanaldehyde should be stored in the dark. Under light, especially direct exposure to strong light, it can promote photochemical reactions, change its chemical structure, and damage its quality. Therefore, it should be placed in a dark container such as a brown bottle and hidden in a dark place.
    Third, the influence of air should not be underestimated. This compound is prone to oxidation reaction with oxygen in the air, so it needs to be sealed and stored. A well-sealed container, such as a glass bottle with a sealed lid, can be used to reduce contact with air, delay the oxidation process, and prolong its shelf life.
    Fourth, humidity also needs to be concerned. If the humidity is too high, 2-methyl-5-furan formaldehyde may absorb moisture, which will affect its purity and stability. It should be stored in a dry place, and a desiccant can be placed in the storage place to maintain the dryness of the environment.
    In this way, follow the storage conditions of cool, dark, sealed and dry, so that 2-methyl-5-furanaldehyde can be better preserved and its original chemical properties and quality can be maintained for a certain period of time.