2 Methoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

2-methoxypyridine

    Specifications

    HS Code

    154048

    Name 2-methoxypyridine
    Molecular Formula C6H7NO
    Molecular Weight 109.13 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 142 - 144 °C
    Melting Point -66 °C
    Density 1.03 g/cm³
    Flash Point 43 °C
    Solubility In Water Slightly soluble
    Odor Characteristic pyridine - like odor
    Pka 6.67

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    General Information
    Where to Buy 2-methoxypyridine in China?
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    Frequently Asked Questions

    As a leading 2-methoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-methoxypyridine?
    2-% Aminoethoxyvinylglycine, its main uses are as follows:
    This is a plant growth regulator with a wide range of uses in agriculture and horticulture. Its core role is to inhibit the biosynthesis of ethylene in plants. As a plant hormone, ethylene has a profound impact on the growth, development and aging process of plants, such as ripening fruits, promoting the aging and withering of leaves and flowers, etc.
    In terms of fruit preservation, 2-% Aminoethoxyvinylglycine has a significant effect. For example, during the storage and transportation of tropical fruits such as bananas and mangoes, appropriate application of this substance can effectively delay the ripening rate of fruits. Due to its inhibition of ethylene synthesis, the respiration rate of fruits is reduced, which delays the appearance of ripening phenomena such as fruit softening, sweetening and color change, greatly prolongs the fresh-keeping time of fruits, reduces the loss caused by premature maturity and rot, and ensures that fruits can be delivered to consumers in good condition.
    In the flower industry, it also plays an important role. Many flowers are prone to rapid withering due to the action of ethylene after harvest, such as carnations, lilies, etc. The use of 2% amino ethoxy vinyl glycine to treat cut flowers can delay the aging of flowers, maintain the brightness and shape of flowers, prolong their vase life, enhance the ornamental value and commercial value of flowers, and make flowers more competitive in the market.
    In addition, in vegetable cultivation, such as tomatoes, the application of 2% amino ethoxy vinyl glycine at a specific stage of growth can regulate the growth and maturation process of plants, optimize fruit quality, increase yield, and help farmers achieve more ideal economic benefits.
    What are the physical properties of 2-methoxypyridine?
    2-% methoxypyridine is an organic compound with unique physical properties. Under normal temperature and pressure, it is a colorless to light yellow transparent liquid, which is clear and pure. This substance has a specific odor. Although it is not pungent or intolerable, it is also unique and can impress the sniffer.
    When it comes to boiling point, 2-% methoxypyridine is in a certain temperature range. This boiling point value makes it change from liquid to gaseous under specific conditions, which is of great significance in separation, purification and related chemical processes. In terms of melting point, it also has its inherent value, which defines the critical temperature for a substance to change from solid to liquid.
    2% methoxypyridine exhibits an affinity for some organic solvents in terms of solubility. For example, in common organic solvents such as ethanol and ether, it can dissolve well to form a uniform solution. However, its solubility in water is relatively limited and only slightly soluble. This difference in solubility provides a basis for its selection in different chemical operations and application scenarios.
    Furthermore, the density of 2% methoxypyridine is also an important physical property. The specific density value requires careful consideration when involving metrology, mixing, etc., to ensure the accuracy of chemical reactions and the reliability of experimental results.
    In addition, its refractive index also has specific values, and this optical property may have potential uses in optical materials, analysis and testing. Through the study of the characteristics of light refraction, it may open up new paths for related scientific research and practical applications. These physical properties are intertwined to build a unique physical property map of 2-% methoxypyridine, laying the foundation for its application in many fields such as chemical industry, medicine, and materials.
    What are the synthesis methods of 2-methoxypyridine?
    There are many synthesis methods of 2-% methoxypyridine, which are described in detail below:
    First, pyridine is used as the starting material. Pyridine first interacts with strong bases such as n-butyl lithium to generate corresponding lithium salt intermediates, which are highly active. Then, it meets methylating reagents such as dimethyl sulfate, and methoxy groups can be introduced to generate 2-% methoxypyridine. This approach is relatively simple, and the starting material pyridine is also relatively common. However, the reaction conditions are quite harsh. When using strong bases, careful operation is required, and the reaction selectivity needs to be carefully regulated to prevent side reactions from breeding.
    Second, starting from 2-halopyridine. 2-Halopyridine can be selected from 2-chloropyridine, 2-bromopyridine, etc. First, it is mixed with alkoxides such as sodium methoxide in a suitable solvent to undergo a nucleophilic substitution reaction. The halogen atom leaves, and the methoxy group replaces it to achieve the synthesis of 2-% methoxy pyridine. The advantage of this method is that the reaction conditions are relatively mild, and the reactivity of halopyridine is easy to control. However, the preparation of halopyridine may require additional steps, and the ability of the halogen atom to leave has a greater impact on the reaction process.
    Third, the coupling reaction is catalyzed by palladium. The coupling of 2-pyridyl boric acid and its derivatives with halomethane is achieved in a basic environment under the catalysis of palladium catalysts such as This reaction has excellent regioselectivity and chemical selectivity, which can efficiently synthesize the target product. However, palladium catalysts are expensive, the reaction cost is high, and the reaction system requires strict anhydrous and anaerobic conditions, and the operation needs to be extremely fine.
    Fourth, the use of pyridine nitrogen oxides. Pyridine is oxidized to form pyridine nitrogen oxides, and then reacts with methylating reagents such as dimethyl sulfate. Methoxy groups are preferentially introduced at the 2-position, and finally the oxygen on the nitrogen oxides is removed by reduction means to obtain 2-% methoxy pyridine. This route can effectively avoid the problem of regioselectivity in the direct reaction of pyridine, but the total yield may be affected by the multi-step reaction, and the oxidation and reduction steps are complicated, so the reaction conditions need to be properly controlled.
    What are the precautions for storing and transporting 2-methoxypyridine?
    For 2-% ethylaminopyridine, there are several ends that should be paid attention to during storage and transportation.
    The first word is storage. This substance should be placed in a cool, dry and well ventilated place. If it is placed in a warm and humid place, it is prone to deterioration. For example, if it is placed in an open sun place, it will cause chemical changes due to heat; if it is placed in a humid place or eroded by water vapor, its purity will be affected. And it must be placed separately from oxidizing agents, acids and other substances, covering 2-% ethylaminopyridine. When encountering such substances, it may cause violent chemical reactions, or even the risk of explosion.
    As for transportation, there are also many details. It needs to be packaged properly to ensure good sealing to prevent leakage. If it leaks during transportation, it will not only damage the environment, but also be harmful to people and animals in contact. Transportation vehicles should be equipped with corresponding emergency treatment equipment, such as adsorption materials, neutralizing agents, etc., just in case. Drivers and escorts should also be familiar with the characteristics and emergency treatment methods of 2-% ethylaminopyridine. In case of emergencies, they can respond quickly and reduce the harm. In addition, the planning of transportation routes should also be careful to avoid densely populated areas and sensitive areas such as water source reserves, so as not to cause large-scale harm when leaking. In short, the storage and transportation of 2-% ethylaminopyridine must be carefully and strictly followed to ensure security.
    What is the market price trend of 2-methoxypyridine?
    In today's world, business conditions are ever-changing, and the market is impermanent. It is not easy to know the market price trend of 2-aminopyridine. However, we can get a glimpse of it from the traces of the past, the current situation, and the measurement of the future.
    Looking at the past, the price of 2-aminopyridine may change due to the times. In the past, due to the abundance of raw materials, the quality of craftsmanship, and the strictness of government orders, the price of 2-aminopyridine fluctuated from time to time. If raw materials are widely available and the supply is plentiful, the price may decline; conversely, if raw materials are scarce, the demand exceeds the supply, and the price will rise. If the process is refined, the production will increase and the cost will decrease, which can also make the price drop; however, the process will encounter difficulties, the cost will be high, and the price will also rise. If the government order provides incentives and support to facilitate its production, the price may be stable; if restrictions are imposed, the cost will increase, and the price will fluctuate.
    As for the current situation, the global situation is complicated, the economic situation is confused, and the chemical industry field is also disturbed by it. 2-Aminopyridine involves many industries, such as medicine, pesticides, and materials. Medicine seeks innovation, and research and development is advancing day by day. If the formation of new drugs requires this material, the demand will increase greatly, and the price is also expected to rise. In terms of pesticides, in response to the needs of the time and the need to prevent diseases and pests, if it is the key to making good medicines, the market demand is not small, and the price may be strong. Material technology is changing with each passing day. If new materials are synthesized based on this, the demand will rise, and the price will be difficult to fall. And the supply and demand vary from place to place. If the supply in the production area is sufficient and the demand is slow, the price may be stagnant; if the sales area is prosperous and the supply is scarce, the price will be high.
    Pushing forward to the future, the progress of science and technology, and the change of the industry are all variables. If the new way is opened, the application will increase widely, and the demand will exceed the supply, and the price will rise. However, if the industry competes, if the new And environmental regulations are becoming stricter, production regulations are getting stricter, compliance costs are increasing, and prices may rise as a result.
    In short, the market price trend of 2-aminopyridine is influenced by factors such as supply and demand, cost, policy, and technology. Businesspeople should consider the situation and observe the micro-knowledge in order to seek profits in the market.