2-METHOXYPYRIDINE-5-CARBONITRILE

2-Methoxypyridine-5-formonitrile has a wide range of uses. In the field of pharmaceutical synthesis, it is often used as a key intermediate. The structure of gainpyridine and formonitrile endows the compound with unique chemical and biological activities, and can be combined with other molecules through various chemical reactions to build complex drug molecular structures. For example, when developing specific anti-inflammatory drugs, it can be used to react with compounds containing active groups to generate specific pharmacologically active drug molecules through multi-step reactions, achieving the purpose of targeted treatment of diseases.
In the field of materials science, 2-methoxypyridine-5-formonitrile also has important uses. Due to its structure containing nitrogen and methoxy groups, it has a unique impact on material properties. When preparing some functional polymer materials, it can be introduced as a monomer or additive to change the electronic structure of the polymer material and the interaction between molecules, thereby improving the properties of the material such as conductivity, optical properties, and thermal stability. For example, when preparing new photoelectric materials, adding this substance in an appropriate amount may improve the photoelectric conversion efficiency of the material, and expand the application of photoelectric devices such as solar cells and Light Emitting Diodes.
In addition, in the study of organic synthetic chemistry, 2-methoxypyridine-5-formonitrile is also a common reagent. With its unique activity check point, it can participate in many organic reactions, such as nucleophilic substitution, cyclization reaction, etc., to help synthesize organic compounds with complex structures and special functions, provide diverse possibilities for the development of organic synthetic chemistry, and promote scientific research in this field.

2-Methoxypyridine-5-formonitrile is an important compound in organic chemistry. Its physical properties are as follows:
This substance is usually in a solid state, mostly white to light yellow crystalline powder, which is easy to identify and distinguish from other substances. Its melting point is in a specific range. After accurate determination, it is about [X] ° C, and the melting point is relatively stable. It is a key indicator for substance identification. It is of great significance for purity analysis and synthesis process control.
2-methoxypyridine-5-formonitrile has different solubility in common organic solvents. In polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), it exhibits good solubility and can quickly and uniformly disperse to form a uniform solution. In non-polar solvents such as n-hexane, the solubility is very poor, insoluble or only slightly soluble. This difference in solubility has far-reaching implications for its separation, purification and choice of reaction solvent.
The density of this compound is also an important physical property. Under standard conditions, the density is about [X] g/cm ³, which reflects the relationship between its mass and volume. It is indispensable for chemical production material measurement and reaction system design.
Its stability is acceptable at room temperature and pressure, but when it encounters strong oxidizing agents, strong acids or strong bases, chemical reactions may occur and structural changes may occur. Avoid such substances when storing, and choose a dry, cool and well-ventilated place to prevent deterioration.
Physical properties of 2-methoxypyridine-5-formonitrile are widely used in organic synthesis, pharmaceutical chemistry and other fields. In organic synthesis, the appropriate reaction conditions and separation methods are selected according to their melting point and solubility. In pharmaceutical chemistry, these properties are related to drug development. For example, drug solubility affects bioavailability, and stability affects the shelf life of drugs. In short, in-depth understanding of its physical properties is of great significance for research and application in related fields.

The synthesis method of 2-methoxypyridine-5-formonitrile has been known for a long time. One of the common synthesis methods is to use pyridine compounds as the starting material and go through specific reaction steps to achieve this target product.
First take the appropriate pyridine derivative and make it meet the methoxylating agent under suitable reaction conditions. This reaction requires fine regulation of the reaction temperature, reaction time and reagent ratio. For example, at a certain temperature, the pyridine derivative is mixed with the methoxylating agent in a certain proportion and reacted in a specific solvent for several hours to successfully integrate the methoxy group into the pyridine ring.
Subsequently, the methoxylated pyridine intermediate is introduced with a cyano group. This step also requires careful operation, selection of appropriate cyanide reagents and reaction environment. With a cyanide reagent, with the help of a catalyst, it can be reacted with intermediates through several steps to obtain 2-methoxypyridine-5-formonitrile.
In addition, other nitrogen-containing heterocyclic compounds are also used as the starting point, and the pyridine ring is gradually constructed through multi-step transformation, and methoxy and cyano are introduced at the same time. Although this path is more complicated, it is also an effective method under specific circumstances. First, the nitrogen-containing heterocyclic ring is skillfully modified to generate a specific structure intermediate, and then cyclization and functional group transformation are carried out to finally achieve the target product. Every step of the reaction requires careful control of the reaction conditions, from the choice of solvent, temperature control, to the addition of catalyst, all of which are related to the success or failure of the synthesis and the yield. Such various synthesis methods have their own strengths, and they need to be selected according to the actual situation, weighing the advantages and disadvantages.

2-Methoxypyridine-5-formonitrile is an organic compound and should be stored with caution. Although its properties are relatively stable, there are many things to be paid attention to.
First, it should be stored in a cool and ventilated place. This compound is easy to decompose due to heat, or cause danger. If it is in a high temperature environment, its chemical structure may be damaged, resulting in a decrease in quality, or even the risk of fire and explosion.
Second, it should be kept away from fires and heat sources. The substance is flammable and can cause combustion in case of open flames and high heat. Therefore, fireworks are strictly prohibited in storage places. Electrical equipment must also be explosion-proof to avoid the danger caused by static electricity.
Third, it needs to be stored separately from oxidants, acids, bases, etc. 2-methoxypyridine-5-formonitrile is chemically active, and contact with these substances may cause severe chemical reactions, resulting in serious consequences such as leakage and explosion.
Fourth, the storage container must be sealed. This compound is exposed to the air or reacts with oxygen, water vapor, etc., which affects the purity and quality. A well-sealed container can prevent its volatilization and deterioration.
Fifth, the storage area should be equipped with suitable materials to contain leaks. Even with comprehensive precautions, it is difficult to prevent accidents. Once a leak occurs, it needs to be dealt with quickly and effectively to avoid polluting the environment and expanding the harm.
In conclusion, when storing 2-methoxypyridine-5-formonitrile, it is necessary to strictly follow safety regulations and operating procedures to ensure personnel safety and material quality.

2-Methoxypyridine-5-formonitrile, the price of this substance in the market is difficult to determine. Its price often varies due to various reasons and cannot be generalized.
First, the difficulty of its preparation is related to the cost, so it has a great impact on the price. If the preparation method is complicated, many rare medicinal materials are required, or the operation process is difficult, and superb skills and precision equipment are required, the cost will be high, and the price will follow. If the opposite is true, the preparation method is simple, and the medicinal materials are usually easy to cause, the price may be slightly cheaper.
Second, the supply and demand of the market is also the main reason. If there is a strong demand for this product in the market, but the supply is limited, the so-called "rare is expensive", the price will rise. If the supply exceeds the demand, the merchant will sell the product or reduce the price to promote it.
Furthermore, different producers have different prices. Famous producers, with their faith and high quality, produce prices that may be slightly higher. And the unknown, in order to compete for market profits, or compete at low prices.
Also, the amount of purchase varies depending on the price. If the buyer is large, the producer may give a discount for small profits but quick turnover, and the price will be reduced accordingly. If the purchase quantity is small, it is difficult to enjoy this benefit.
To sum up, if you want to know the exact price of 2-methoxypyridine-5-formonitrile in the market, you must carefully consider the preparation, supply and demand, production, purchase quantity, etc. If you want to know the quasi-price, you can consult the chemical material supplier, or check the recent transaction price on the chemical trading platform, and you can get a near-real price.