2 Methoxymethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-(methoxymethyl)pyridine

    Specifications

    HS Code

    667906

    Chemical Formula C7H9NO
    Molar Mass 123.15 g/mol
    Appearance Liquid (usually)
    Boiling Point Approx. 186 - 188 °C
    Density Approx. 1.04 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Odor Typical pyridine - like odor
    Flash Point Approx. 65 °C

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    General Information
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    Frequently Asked Questions

    As a leading 2-(methoxymethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2- (methoxymethyl) pyridine?
    2-%28methoxymethyl%29pyridine is 2- (methoxy methyl) pyridine, which has a wide range of uses.
    In the field of medicine, it is a key intermediate. Compounds with specific biological activities can be prepared through a series of reactions, and many antibacterial and antiviral drugs are synthesized based on it as the starting material. For example, in the development of a new type of antibacterial drug, 2- (methoxy methyl) pyridine is used as the base, and after modification and transformation, it has obtained a structure with high antibacterial activity, which acts on specific bacterial targets, adding a new path for the treatment of infectious diseases.
    In the field of pesticides, it also plays an important role. Can derive a variety of insecticides and fungicides. With it as the starting material, chemical modification of pesticide components containing pyridine structure can be obtained. Such ingredients have strong contact and stomach toxicity effects on pests, or have inhibitory and killing effects on plant diseases, which can help agricultural pest control and ensure crop yield and quality.
    In addition, in the field of materials science, 2- (methoxy methyl) pyridine can participate in the synthesis of functional materials. For example, the preparation of polymer materials with special optical and electrical properties, the pyridine ring and methoxy methyl structure can endow the material with unique properties, which can be used in organic Light Emitting Diodes, sensors and other fields, injecting new vitality into the development of materials science.
    In summary, 2- (methoxymethyl) pyridine has important uses in medicine, pesticides, materials science and other fields due to its unique structure, which is of great significance to the development of related industries.
    What are the physical properties of 2- (methoxymethyl) pyridine
    2 - (methoxymethyl) pyridine, its physical and chemical properties are as follows:
    When viewed at room temperature and pressure, this substance is mostly colorless to light yellow liquid. When viewed in sunlight, it seems to be clear of glaze, with a faint luster. Its smell is special and slightly irritating. It can feel a different smell when smelled. Although it is not pungent or intolerable, it is also distinct.
    When it comes to the melting point, the melting point is quite low, and it can still maintain a liquid state of circulation in common low-temperature environments. The boiling point is relatively moderate. If heated at a proper temperature, it can be seen that it slowly vaporizes and rises, just like water vapor. This substance has a certain solubility in water, just like a fish entering water, some of it can blend with water, but it is not completely seamless, showing a certain hydrophilicity and partial hydrophobicity.
    Its density is slightly smaller than that of water. If it is placed in the same place as water, it can be seen that it floats leisurely on the water, like a boat wave. In organic solvents, such as ethanol and ether, its solubility is very good, and it can be quickly blended with it, just like water milk blending.
    In addition, 2 - (methoxymethyl) pyridine has a certain chemical activity, and under suitable conditions, it can participate in many chemical reactions, like a smart dancer, performing various changes on the chemical stage. It is an important raw material for organic synthesis and plays an important role in many chemical fields.
    What are the chemical synthesis methods of 2- (methoxymethyl) pyridine
    To prepare 2 - (methoxymethyl) pyridine, there are several common methods.
    First, 2 - chloromethylpyridine is used as the raw material. 2 - chloromethylpyridine and sodium methoxide are placed in a suitable reaction vessel, with a suitable organic solvent such as N, N - dimethylformamide (DMF) as the medium, and controlled at a suitable temperature, usually between 40 and 60 ° C. Nucleophilic substitution reaction occurs between the two. Among them, the methoxyradical of sodium methoxide attacks the chloromethyl of 2 - chloromethylpyridine, and the chlorine atom leaves, so 2 - (methoxymethyl) pyridine is obtained. The reaction mechanism is clear and the operation is relatively simple. However, the acquisition of 2-chloromethylpyridine requires a pre-step, and the separation and purification of the product after the reaction requires fine operation.
    Second, 2-hydroxymethylpyridine is used as the starting material. React 2-hydroxymethylpyridine with dimethyl sulfate in an alkaline environment. A base such as potassium carbonate can be selected and heated to 50-70 ° C in a solvent such as acetonitrile. Dimethyl sulfate provides methyl, and methylates with the hydroxyl group of 2-hydroxymethylpyridine to obtain the target product. In this process, the regulation of the alkaline environment is very critical, and too strong or too weak bases can affect the reaction process and yield. Dimethyl sulfate has certain toxicity and corrosiveness, and it must be carefully protected during operation.
    Third, 2-methylpyridine is used as the starting material. First, through oxidation reaction, such as using suitable oxidants, such as hydrogen peroxide and suitable catalysts, the methyl of 2-methylpyridine is oxidized to hydroxymethyl to obtain 2-hydroxymethyl pyridine. Then, as above, it is reacted with methylation reagents such as dimethyl sulfate to obtain 2 - (methoxymethyl) pyridine. This route has a little more steps, but the starting material 2-methylpyridine is relatively widely sourced. Each method has its advantages and disadvantages, and the actual synthesis needs to be weighed by factors such as raw material availability, cost, yield and product purity.
    2- (methoxymethyl) pyridine during storage and transportation
    2-%28methoxymethyl%29pyridine is 2 - (methoxymethyl) pyridine. Many things need to be paid attention to when storing and transporting this product.
    First, when storing, find a cool, dry and well-ventilated place. Because of its flammability, if placed near high temperature or fire sources, it is easy to cause fire, so be sure to keep away from heat sources and open flames. The temperature of the warehouse should also be properly controlled, not too high, to prevent changes in material properties.
    Second, the packaging must be tight. This product may be more sensitive to air and moisture. If the packaging is not strict, moisture will invade, or cause it to react such as hydrolysis, which will affect the quality. Store in a sealed container and ensure that the container is not damaged or leaked.
    Third, during transportation, follow the relevant regulations on the transportation of hazardous chemicals. Transport vehicles need to have corresponding safety protection measures, such as fire extinguishing equipment. Escort personnel should also be familiar with the characteristics of this substance and emergency treatment methods to prevent accidents.
    Fourth, isolation from other substances is also critical. 2- (methoxymethyl) pyridine should not be mixed or mixed with strong oxidizing agents, strong acids and other substances, because it comes into contact with it, or causes violent chemical reactions, endangering safety.
    In conclusion, whether it is storing or transporting 2 - (methoxymethyl) pyridine, it is necessary to strictly follow safety regulations and operating procedures, and exercise caution to ensure the safety of people and the environment.
    What is the market outlook for 2- (methoxymethyl) pyridine?
    2-%28methoxymethyl%29pyridine is 2 - (methoxy methyl) pyridine, which has a promising future in the chemical raw material market.
    In today's chemical industry, the demand for fine chemicals is growing. 2 - (methoxy methyl) pyridine, as a key organic intermediate, is widely used in many fields such as medicine, pesticides and materials science.
    In the field of medicine, it is the cornerstone of the synthesis of many kinds of specific drugs. Today, human beings need to fight diseases urgently, and new drug development is non-stop. 2 - (methoxy methyl) pyridine is indispensable in the process of innovative drug development because of its unique chemical structure, which can help chemists construct complex and biologically active molecules. This is where its bright future lies in the pharmaceutical market.
    As for the field of pesticides, with the deepening of people's attention to food safety and environmental protection, the development of high-efficiency and low-toxicity pesticides has become the general trend. 2 - (methoxymethyl) pyridine can provide a key structural unit for the creation of new pesticides, and help synthesize pesticide products with high selectivity, strong biological activity and environmental friendliness. Therefore, in the pesticide market, it also has a wide range of applications.
    Furthermore, materials science is booming, and new functional materials are constantly emerging. 2 - (methoxymethyl) pyridine can participate in the synthesis of functional polymers and organic semiconductor materials, injecting new vitality into materials science. With the advancement of science and technology, the demand for high-performance materials continues to rise, and the application of 2- (methoxymethyl) pyridine in the field of materials will be more extensive.
    In summary, 2- (methoxymethyl) pyridine, with its important uses in many fields, has a bright future in today's chemical raw material market. The future development space is extremely broad, and it is expected to play a major role in the upgrading and innovation process of various related industries.