2 Methoxyethyl 2 6 Dimethyl 4 3 Nitrophenyl 5 2e 3 Phenylprop 2 En 1 Yl Oxy Methyl 1 4 Dihydropyridine 3 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

2-methoxyethyl 2,6-dimethyl-4-(3-nitrophenyl)-5-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)-1,4-dihydropyridine-3-carboxylate

    Specifications

    HS Code

    639860

    Chemical Formula C30H30N2O7
    Molecular Weight 530.57
    Appearance Solid (predicted)
    Solubility Insoluble in water (predicted)
    Logp 4.78 (predicted)

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    Frequently Asked Questions

    As a leading 2-methoxyethyl 2,6-dimethyl-4-(3-nitrophenyl)-5-({[(2E)-3-phenylprop-2-en-1-yl]oxy}methyl)-1,4-dihydropyridine-3-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate
    This is the chemical name of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) - 5 - ({[( E) -3 -phenylpropyl-2-alkene-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate. To clarify its chemical structure, let me explain it in detail.
    Looking at this name, the core of this compound is a 1,4-dihydropyridine ring. The 2 and 6 positions on the ring are each connected with a methyl group, and the two are like left and right protectors to stabilize its structure. The 4-position is connected with a 3-nitrophenyl group, which is like a flag and gives the molecule different properties. The part connected to the 5-position is more complex, which is ({[ (E) -3 -phenylpropyl-2-ene-1-yl] oxy} methyl), where (E) -3 -phenylpropyl-2-ene-1-group has an unsaturated double bond and contains a benzene ring, which makes the molecular structure more abundant. The oxygen group is connected between this alkenyl group and the methyl group, forming a unique branch chain.
    Furthermore, the 3-position is connected with a carboxylic acid ester structure, specifically 2-methoxyethyl ester. This 2-methoxyethyl group is formed by linking methoxy group to ethyl group, and is partially connected to carboxylic acid to form this carboxylic acid ester.
    Such various structural units are connected by the wonderful hands of chemistry to form this complex and unique chemical structure. The parts of this structure interact with each other, or cause the molecule to have special physical and chemical properties, which may be used in chemistry, medicine and other fields.
    What are the physical properties of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate
    2-Methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylpropyl-2-alkenyl-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylic acid ester, this is an organic compound with unique physical properties. It is mostly solid at room temperature and has high stability. The chemical bond energy in its molecular structure is relatively large, and the interatomic bonding is stable.
    Looking at its solubility, the compound exhibits good solubility in organic solvents such as ethanol and dichloromethane. Due to the formation of van der Waals forces, hydrogen bonds and other forces between organic solvents and compound molecules, it can help it disperse and dissolve. However, in water, the solubility is very small. Due to the strong hydrophobicity of the molecular structure, the force between water molecules and compound molecules is difficult to defeat the interaction between compound molecules, so it is not easily soluble.
    When it comes to the melting point, it has been experimentally determined that the melting point of the compound is within a certain range. This melting point characteristic is closely related to the intermolecular force. The stronger the intermolecular force, the higher the energy required to separate the molecules, and the higher the melting point. There are various interactions between the molecules of the compound, resulting in a specific melting point.
    Again, the density is also a specific value, which is determined by the molecular weight of the compound and the degree of compaction of the molecules. If the molecular mass is large and the packing is tight, the density is relatively large.
    The physical properties of this compound lay an important foundation for its application in chemical synthesis, drug development and other fields. In chemical synthesis, suitable solvents can be selected for reaction according to their solubility; in drug development, properties such as melting point and density are closely related to drug stability and dosage form preparation.
    What is the synthesis method of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate
    The synthesis of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1, 4-dihydropyridine-3-carboxylate is the key to organic chemistry.
    Prepare raw materials such as 3-nitrobenzaldehyde, 2-methoxyethyl acetoacetate, 2-methyl-3-phenylacrylic aldehyde, and ammonium acetate. In the reactor, add an appropriate amount of organic solvent, such as ethanol or toluene, mix 3-nitrobenzaldehyde and 2-methoxyethyl acetoacetate in a certain proportion, and stir well. Then an appropriate amount of ammonium acetate is added as a catalyst, and the temperature is raised to a specific temperature, about 80-100 degrees Celsius. During the reaction, the aldehyde group and the ester group undergo a condensation reaction.
    After this step is completed, slightly cool, slowly add 2-methyl-3-phenylacronaldehyde, and then adjust the temperature to 60-80 degrees Celsius, and continue to stir the reaction. In this process, the double bond of the alkenaldehyde and the previous product undergo an addition reaction to form a key intermediate.
    After the reaction is completed, the organic solvent is removed by vacuum distillation, and then separated by column chromatography or recrystallization to purify the product. When separating by column chromatography, appropriate silica gel is selected as the stationary phase, and a specific proportion of petroleum ether and ethyl acetate mixture is used as the mobile phase, and the polarity difference between the product and the impurity is used to separate it. During recrystallization, select a suitable solvent, such as ethanol-water mixed solvent, heat and dissolve the product, cool the crystallization, and filter to obtain pure 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1, 4-dihydropyridine-3-carboxylate. In this way, it can become a great cause of synthesis.
    What are the application fields of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate
    2-Methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1, 4-dihydropyridine-3-carboxylate, this is an organic compound, which is useful in the fields of medicine and materials.
    In the field of medicine, its role is like a good medicine that can clear the body and remove blood stasis. Because the structure contains 1,4-dihydropyridine fragments, it is like the key structure of many calcium channel blockers, or can regulate the flow of calcium ions inside and outside the cell. Calcium channel blockers can relax the smooth muscle of blood vessels, just like opening the meridians and allowing the blood vessels to be unobstructed, so the compound may have the effect of lowering blood pressure and can treat hypertension. And because it can regulate calcium ions, or has the function of regulating the rhythm of the cardiovascular system, it can be used for the prevention and treatment of heart diseases such as arrhythmia. In addition, on the nervous system, or can stabilize nerve cell membranes, it may relieve nerve excitation, or can be used for the adjuvant treatment of certain nervous system diseases.
    In the field of materials, due to its organic structure characteristics, or with specific optical and electrical properties. If its molecules are arranged in an orderly manner, it can be used in optical materials like delicate crystals, such as making special optical lenses, which can change the path or characteristics of light propagation. From an electrical perspective, it may be used for the research and development of organic semiconductor materials, which may build a microscopic circuit bridge, contribute to the miniaturization and flexibility of electronic devices, or make a name for itself in the future in fields such as flexible displays and wearable electronic devices.
    What is the safety of 2-methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1,4-dihydropyridine-3-carboxylate
    2-Methoxyethyl 2,6-dimethyl-4- (3-nitrophenyl) -5- ({[ (2E) -3-phenylprop-2-en-1-yl] oxy} methyl) -1, 4-dihydropyridine-3-carboxylate, this substance is a more complex organic compound. Looking at its structure, it is composed of a combination of multiple groups and contains groups such as methoxyethyl, dimethyl, nitrophenyl, allyloxy methyl and dihydropyridine carboxylic acid esters.
    Discussing safety, first, from the perspective of chemical structure, nitro-containing 3-nitrophenyl, nitro has strong oxidizing properties. If this compound comes into contact with reducing substances, or is dangerous due to redox reactions, it may explode in case of open flame or hot topic. Second, the presence of allyl structure, because of its carbon-carbon double bond, chemical activity, prone to addition, polymerization and other reactions, under specific conditions, or cause system instability, increasing safety risks. Third, as an organic ester, in the acid-base environment, prone to hydrolysis, if hydrolyzed in the human body or the environment, the resulting products may have different toxicity and reactivity, affecting safety. Fourth, for this compound, although there is no exact data indicating its direct toxicity to the human body, in view of the fact that organic compounds are often fat-soluble, easily penetrate biofilms, or pose potential hazards to organisms, such as entering the human body through respiratory tract and skin contact, or interfering with the normal biochemical processes in the organism, affecting cell function, long-term exposure may pose a risk of toxicity, teratogenicity, and carcinogenesis.
    In terms of storage, because it has a variety of active groups, it needs to be stored in a cool and well-ventilated place, away from fire and heat sources, and avoid mixing with oxidants, reducing agents, acids, bases and other substances to prevent dangerous reactions. During use, the operator must take strict protective measures, such as wearing appropriate protective gloves, goggles, gas masks, etc., to ensure that the operating environment is well ventilated to ensure safety.