2 Methoxy N 3 Dimethyl N Phenylpyridine 4 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

2-Methoxy-N,3-dimethyl-N-phenylpyridine-4-carboxamide

    Specifications

    HS Code

    223796

    Chemical Formula C15H18N2O2
    Molecular Weight 258.32 g/mol
    Appearance Solid (usually)
    Melting Point Varies, needs experimental determination
    Boiling Point Varies, needs experimental determination
    Solubility In Water Low (organic compound)
    Solubility In Organic Solvents Good in many organic solvents like ethanol, chloroform
    Density Needs experimental determination
    Pka Data may vary depending on environment
    Logp Estimated to be positive, indicating lipophilicity
    Odor Typical organic compound odor (description may vary)

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-carboxamide?
    The chemical structure of 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide is analyzed according to its naming rules. "Pyridine" is a nitrogen-containing six-membered heterocyclic compound, which is the core skeleton of the molecule. "4-formamide" indicates that a formamide group is connected at the 4th position of the pyridine ring, that is, the -CONH-structure, and the nitrogen atom is the connection check point. "N, 3-dimethyl" means that the nitrogen atom of the formamide group is connected to a methyl group at the 3rd position of the pyridine ring, and the methyl group is -CH. " 2-Methoxy "refers to the methoxy group attached to the second position of the pyridine ring, and the methoxy group structure is -OCH < unk >." N-phenyl "indicates that the nitrogen atom of the formamide group is still connected to a phenyl group, and the phenyl group is the remaining part after removing a hydrogen atom from the benzene ring, with the -C < unk > H < unk > structure. Overall, the chemical structure of this compound is centered on the pyridine ring, with methoxy at the 2nd position, methyl at the 3rd position, and formamide at the 4th position. The nitrogen atom of the formamide group is connected with methyl and phenyl. In this way, each group forms the unique chemical structure of 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide according to the specific position and connection mode.
    What are the main uses of 2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-carboxamide
    2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. Due to its specific chemical structure and properties, it can be converted into compounds with specific biological activities through a series of chemical reactions for the development of new drugs. For example, in the development of anti-cancer drugs, the compound may be modified and modified to generate substances that target cancer cells, interfere with the growth and proliferation of cancer cells, and provide the possibility of conquering cancer.
    It also has important applications in the field of materials science. With its unique molecular structure, it may be able to participate in the preparation of materials with special properties. For example, in the preparation of optical materials, it may improve the optical properties of materials, so that the materials have better absorption and emission characteristics for specific wavelengths of light, and be applied to optical sensors, Light Emitting Diodes and other optoelectronic devices to improve device performance and function.
    In addition, in the field of agricultural chemistry, it may be used as a lead compound to optimize the structure and develop new pesticides. These pesticides may have high inhibitory and killing effects on specific pests and pathogens, and have a small impact on the environment, contributing to sustainable agricultural development and ensuring crop yield and quality. In conclusion, 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide has important potential applications in many fields, and brings many possibilities for scientific research and industrial production.
    What is the synthesis method of 2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-carboxamide
    The synthesis method of 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide is a crucial research in the field of organic synthesis. Due to its unique chemical structure, this compound has shown potential application value in many fields such as drug development and materials science. Its synthesis method can usually be achieved by multi-step reaction.
    The selection of starting materials is very critical. Compounds with pyridine structure and reagents containing methoxy, methyl and phenyl functional groups are often selected. For example, a 4-halogenated pyridine-4-carboxylic acid derivative can be initiated, and the carboxyl group is converted into an ester group through an esterification reaction. Common reagents such as methanol and concentrated sulfuric acid are heated to form a pyridine-4-carboxylic acid methyl ester derivative.
    Subsequently, N-alkylation is carried out. Select a suitable alkylation reagent, such as iodomethane or dimethyl sulfate, in the presence of a base (such as potassium carbonate), to achieve the introduction of the 3-position methyl group. This step requires attention to the control of reaction temperature and time to prevent excessive alkylation or side reactions.
    Then with an appropriate amination reagent, such as N-methylaniline, under the action of a catalyst (such as copper salt or palladium salt), the amidation reaction occurs with the methyl pyridine-4-formate derivative to construct the N-phenyl-N-methylamide structure. Optimization of reaction conditions is particularly important to improve the yield, such as the reaction solvent, temperature and catalyst dosage need to be fine-tuned.
    Finally, 2-methoxy is introduced through the methoxylation reaction. Commonly used methoxylating reagents such as sodium methoxide or dimethyl carbonate can complete the synthesis of the final product 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide under suitable reaction conditions.
    During the synthesis process, the product of each step needs to be separated and purified. Common methods such as column chromatography and recrystallization are used to ensure the purity of the product and meet the needs of subsequent research and application. Although the steps of this synthesis method are complicated, rational design and optimization can provide an effective way for the preparation of the compound.
    What are the physical properties of 2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-carboxamide
    2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide, this is an organic compound. Its physical properties are quite important and often need to be considered in the fields of chemical industry, pharmaceutical research and development.
    Looking at its properties, it is mostly white to quasi-white crystalline powder under normal circumstances. This form is easy to store and transport, and is easily dispersed in many reaction systems, which is conducive to the reaction. Its melting point is about [X] ° C. This characteristic can be used for purity identification. Due to the fixed melting point of pure substances, if the melting point of the sample matches the standard value or the deviation is very small, it can be preliminarily determined that the purity is higher.
    In terms of solubility, the substance exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), and can quickly dissolve to form a uniform solution, which is conducive to participating in various reactions as a reactant or intermediate in organic synthesis. However, the solubility in water is very small, due to the fact that its molecular structure contains many hydrophobic groups, resulting in poor hydrophilicity.
    In addition, the density of 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide is about [X] g/cm ³, which is of great significance in the process of reactant ratio and product separation. Knowing the density helps to accurately control the relationship between the volume and quality of the reaction system, and then optimize the reaction conditions and product yield. At the same time, its stability cannot be ignored. Under normal conditions, stored in a dry and cool place, the substance can maintain relatively stable structure and properties. However, in the case of strong acid, strong alkali or high temperature environment, chemical reactions may occur, resulting in structural changes and affecting its application effect.
    How safe is 2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-carboxamide?
    2-Methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide is an organic compound. To discuss its safety, a multi-faceted view is required.
    First physical and chemical properties. The morphology, melting point, boiling point, solubility and other characteristics of this substance have a great impact on its stability and reactivity in different environments. If the melting point is too low, it may be liquid at room temperature, which is more volatile and may increase risk during storage and use; if the solubility is specific, it will quickly dissolve and react in a specific solvent, which will also affect its safety.
    Times and toxicity. Oral, percutaneous or inhalation routes into the body, or cause various toxic effects. Animal experiments can detect its acute toxicity, and observe its lethal dose and poisoning symptoms to experimental animals. If the acute toxicity is high, a small amount of exposure may be life-threatening. Long-term toxicity studies are concerned with its chronic effects, such as whether it is carcinogenic, teratogenic, and mutagenic. If there is such potential harm, even a small amount of long-term exposure may cause damage to the genetic material of the organism, resulting in irreversible consequences.
    Environmental safety. If this substance is released into the environment, the migration and transformation of it in air, water, and soil need to be investigated in detail. In the soil, or affect the soil microbial community, damage the soil ecological balance; in the water body, or affect the survival and reproduction of aquatic organisms, enrichment through the food chain, and ultimately endanger human health.
    And there is a risk of combustion and explosion. In case of open flames, hot topics, this material can be combustible, or even explode, and its combustion products may contain toxic and harmful gases, such as nitrogen oxides, carbon monoxide, etc., which pollute the air and endanger surrounding organisms and the environment.
    In summary, the safety of 2-methoxy-N, 3-dimethyl-N-phenylpyridine-4-formamide is influenced by many factors, and rigorous scientific research and evaluation are required to know its latent risk in different scenarios, so as to take appropriate protective and management measures to protect human health and environmental safety.