2-METHOXY-3-IODOPYRIDINE

2-Methoxy-3-iodopyridine has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Gein iodine atoms are highly active and can participate in a variety of chemical reactions, such as coupling reactions. Through the coupling reaction catalyzed by palladium, it can be combined with boric acid compounds containing alkenyl and aryl groups to form carbon-carbon bonds. This is of great significance for the synthesis of complex pyridine derivatives. Many biologically active drug molecules and functional materials are constructed by this pathway.
And because of the presence of methoxy groups, it can affect the distribution of molecular electron clouds, change the electron density of pyridine rings, and then affect the reaction activity and selectivity. In the field of medicinal chemistry, 2-methoxy-3-iodopyridine can be structurally modified to derive a series of compounds with potential biological activities. Some studies have shown that the derivatives prepared from this starting material exhibit inhibitory activity on specific cancer cell lines, and may become the direction of anti-cancer drug research and development.
Furthermore, in the field of materials science, the pyridine compounds synthesized by it can be used to prepare organic optoelectronic materials. Due to its unique electronic structure, it may endow materials with excellent optical and electrical properties, such as applied to organic Light Emitting Diodes (OLEDs), or can improve the luminous efficiency and stability of devices.
In summary, 2-methoxy-3-iodopyridine plays an important role in many fields such as organic synthesis, drug development and materials science, and provides broad application prospects for scientific research and industrial production.

2-Methoxy-3-iodopyridine is one of the organic compounds. Its physical properties are numerous.
In terms of its properties, at room temperature, it is mostly solid or crystalline, due to the force between molecules. Its color is often white or nearly white, which is the result of the absorption and reflection of light by the atoms and chemical bonds in the structure.
As for the melting point, it is within a certain range. This value depends on the degree of close arrangement of molecules and the size of the lattice energy. Interactions such as van der Waals forces and hydrogen bonds between molecules jointly determine the melting point. When heating up, the lattice vibration intensifies, and when the energy is sufficient to overcome the lattice binding, the substance melts into a liquid state.
The boiling point is also an important physical property. Due to factors such as the polarity and relative molecular mass of the molecule, the intermolecular forces are different, and the boiling point also has a specific value. When heated, the kinetic energy of the molecule increases, overcoming the attractive force between the molecules to escape from the liquid level, reaching a specific temperature, the liquid phase and the gas phase are in equilibrium, and this temperature is the boiling point.
In terms of solubility, it may have a certain solubility in organic solvents such as dichloromethane and ethanol. Due to the principle of similar compatibility, the molecular structure of 2-methoxy-3-iodopyridine has a similar polarity to that of organic solvents or can form intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., and can be dissolved. In water, the solubility may be limited due to differences in polarity and interactions with water molecules.
density is also one of its physical properties, reflecting the amount of mass per unit volume and related to the degree of molecular accumulation. This value is also of great significance for the study of the behavior of substances in different environments.

The chemical synthesis methods of 2-methoxy-3-iodine pyridine have many different paths. One of the common ones is to use 2-methoxy pyridine as the starting material. This pyridine compound is first treated with an appropriate protective group to adjust the activity at a specific position. Then, under suitable reaction conditions, iodine atoms are introduced. If an iodine source, such as iodine elemental or other iodine-containing reagents, reacts with the protected 2-methoxy pyridine in the presence of a catalyst. The catalyst can be selected from copper salts, such as cuprous iodide. In an alkaline environment, iodine atoms can be selectively attached to the third position of the pyridine ring. Alkaline conditions can be created by alkali metal carbonates such as potassium carbonate. The reaction temperature and time need to be carefully regulated. If the temperature is too high or side reactions occur, if it is too low, the reaction will be slow and the efficiency will be poor. Generally speaking, the temperature is usually controlled between tens of degrees Celsius and 100 degrees Celsius, and the reaction takes several or even ten hours.
Furthermore, there are also those who use 3-iodopyridine as the starting material. First hydroxylate it to obtain 3-iodo- 2-hydroxypyridine. Subsequently, methylation of hydroxyl groups is achieved with methylating reagents such as dimethyl sulfate or iodomethane under the action of alkali, and 2-methoxy-3-iodopyridine is obtained. Sodium hydroxide or potassium carbonate can be selected as the base. In this reaction process, the reaction conditions should also be paid attention to to to ensure the purity and yield of the product. The choice of reaction solvent is also key, and polar organic solvents such as N, N-dimethylformamide (DMF), dichloromethane, etc. are often selected to facilitate the dissolution of the reaction substrate and the reaction process. After each reaction step, the product is often purified by means of column chromatography, recrystallization, etc., to achieve the desired purity.

2-Methoxy-3-iodopyridine is an organic compound. When storing and transporting, pay attention to the following things:
First, the storage environment. This compound should be placed in a cool, dry and well-ventilated place, away from fires and heat sources. Because it may be sensitive to heat, high temperature or decomposition, or even cause danger. Be sure to avoid direct sunlight, as it may promote photochemical reactions and affect the stability of the compound.
Second, packaging material. When storing and transporting, choose the appropriate packaging material. Usually in glass bottles or specific plastic containers, ensure that the packaging is tight to prevent leakage. For 2-methoxy-3-iodopyridine, the packaging material must not chemically react with it to avoid the interaction between the material and the compound and cause it to deteriorate.
Third, isolate from other substances. Do not mix with oxidants, acids, bases and other substances. Because of its chemical properties or cause violent reactions with these substances, cause safety accidents. Such as oxidants or oxidation of 2-methoxy-3-iodopyridine, or serious consequences such as fire and explosion.
Fourth, careful handling. During the handling process, the operator should pack and unload lightly, do not drop or heavy pressure, to prevent package damage and leakage. When working, wear appropriate protective equipment, such as protective gloves, goggles, etc., to avoid direct contact.
Fifth, follow regulations. Storage and transportation must strictly follow relevant laws, regulations and standards, such as hazardous chemicals management regulations. Relevant units and personnel should be familiar with and abide by these regulations to ensure the legal compliance of the entire process and ensure the safety of personnel and the environment.

2-Methoxy-3-iodopyridine, its market is determined by its precision, and it is influenced by a variety of factors.
The first factor is the supply and demand. If this material is in a multi-domain, such as synthesis, material research, etc., the demand is strong, and the supply is limited, and the supply will be high; on the contrary, if the demand is low, the supply will be abundant, and the price will drop.
Furthermore, the cost of production also depends on the cost. The cost of raw materials, the ease of production, and the amount of energy consumption all affect the cost. The scarcity of raw materials, or the need for exquisite methods, the cost is high, and the price is also higher.
The difference between manufacturers and places also plays a role. The technical level and strategy of different manufacturers are different, and the cost is different in different places, resulting in waves in various cities.
According to history, there were similar compounds in the past, due to the surge in demand caused by new uses, and the price has doubled; also due to the new industry, the cost has dropped, and the price has dropped sharply.

The market value of 2-methoxy-3-iodopyridine may range from 10 yuan to 100 yuan per gram. However, the price of this product is omitted, and the price needs to be based on the market situation and transaction data.