2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

To prepare 2-methoxy-3- (4,4,5,5-tetramethyl-1,3,2-dioxoboropentane-2-yl) pyridine, the following synthesis method can be followed.
First take a suitable pyridine derivative and react it with a methoxy-containing reagent under suitable reaction conditions to introduce a 2-methoxy group. This reaction requires attention to the reaction temperature, the choice of solvent, and the molar ratio of the reactants. Commonly used methoxy-containing reagents, such as the combination of methyl halide and base, can effectively undergo substitution reactions in suitable organic solvents, such as N, N-dimethylformamide (DMF) or dichloromethane, so that the second position of the pyridine ring is successfully connected to the methoxy group.
Then, for the introduction of 3- (4,4,5,5-tetramethyl-1,3,2-dioxaboro-heterocyclopentane-2-yl) parts, boron reagents can be used to react with them. Boron reagents such as pinacol borane or diphenacol borate are usually used to react in an alkaline environment under the catalysis of transition metal catalysts such as palladium catalysts. Commonly used palladium catalysts include tetrakis (triphenylphosphine) palladium, and potassium carbonate and sodium carbonate can be selected as bases. This reaction can be carried out in organic solvents such as toluene and dioxane. By optimizing the reaction conditions, including temperature, reaction time and catalyst dosage, the coupling reaction between the 3-position of the pyridine ring and the boron reagent can be promoted, and the target 3- (4,4,5,5-tetrakis-1,3,2-dioxaboronacyclopentane-2-yl) structure can be successfully introduced.
After each step of the reaction is completed, suitable separation and purification methods, such as column chromatography, recrystallization, etc., are required to obtain high-purity intermediate products and final products to ensure the smooth progress of the synthesis route and the quality of the products.

2-% methoxy-3- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) pyridine, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, it can react with many nucleophiles or electrophiles by virtue of the reactivity of the boron heterocyclopentane part in the construction of complex organic molecular structures, thereby realizing the construction of carbon-carbon bonds or carbon-heteroatomic bonds, thereby assisting in the synthesis of various drugs, natural products and functional materials.
In the field of pharmaceutical chemistry, using this as a starting material, compounds with specific biological activities can be carefully prepared through multi-step reactions. For example, in the design and synthesis of some small molecule inhibitors targeting specific disease targets, 2-% methoxy-3- (4,4,5,5-tetramethyl-1,3,2-dioxaboron heterocyclopentane-2-yl) pyridine can be used as an important building block to optimize the activity, selectivity and pharmacokinetic properties of compounds by ingeniously introducing different functional groups, paving the way for the development of new drugs.
In the field of materials science, with the help of its functional materials involved in reaction synthesis, it has shown unique properties in the field of optoelectronics. For example, some conjugated polymer materials synthesized, or due to the introduction of the structural unit, have excellent fluorescence properties, charge transport properties, etc., which can be applied to organic Light Emitting Diodes (OLEDs), organic solar cells and other devices to promote the development of materials science.

2-% methoxy-3- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) pyridine, which is an important intermediate in organic synthesis, has unique physical properties.
Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder, with fine appearance and uniform texture. Its stability is quite good, and it can maintain its own chemical structure in a conventional environment, and it is not prone to spontaneous chemical reactions. However, it should be paid attention to its sensitivity to air, humidity and temperature. In humid air, it may slowly absorb moisture, affecting its purity and reactivity; when the temperature is too high, it may cause its decomposition, so it should be stored in a dry, cool and well-ventilated place. < Br >
When it comes to solubility, this compound exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), and tetrahydrofuran (THF), which makes it convenient to dissolve it in a suitable solvent in an organic synthesis reaction to construct a homogeneous reaction system, which is conducive to the smooth progress of the reaction. However, its solubility in water is very small, and this characteristic can be exploited in the process of separation and purification, and it can be separated from water-soluble impurities through the extraction operation of aqueous and organic phases.
Melting point is also one of its key physical properties, and accurate melting point data is of great significance to identify the purity of this compound. The higher the purity, the narrower the melting point range and the closer to the theoretical value. By measuring the melting point, it can quickly determine whether it meets the Quality Standard. If the measured melting point deviates greatly from the theoretical value, or implies that it contains impurities, further purification is required.

This is an organic compound, and its properties are quite complex. The compound contains specific substituents, which have a significant impact on its chemical properties.
From the structural point of view, the 2-methoxy part changes the electron cloud density of oxygen atoms due to the power supply of methyl groups, which affects the reactivity of atoms connected to it. This structure or molecular lipophilicity plays a role in some organic reactions and material transport processes.
And the 3 - (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-yl) part, the dioxaboronheterocyclopentane structure has unique reactivity. The electron-deficient nature of the boron atom makes this part easy to react with nucleophiles, which is common in transition metal catalytic coupling reactions, such as the Suzuki reaction. In this reaction, the compound can be used as an aryl borate reagent to form carbon-carbon bonds with halogenated aromatics under the action of palladium catalysts and bases, and to construct complex organic molecular structures.
In addition, the substitution of tetramethyl groups affects the molecular steric hindrance. Greater steric hindrance may hinder some reactions or change the reaction selectivity, causing the reaction to tend in a specific direction and generate products of a specific configuration.
This compound exhibits diverse chemical properties due to the synergistic effect of different structural parts, and is widely used in the field of organic synthesis. It can be used to construct organic molecules with specific structures and functions, providing key intermediates for new drug development, materials science, and many other fields. It helps to create novel organic materials and bioactive molecules.

The material sought by the viewer is called 2-methoxy-3- (4,4,5,5-tetramethyl-1,3,2-dioxaboronheterocyclopentane-2-based). However, this material is in the market, and its price range cannot be determined at a step.
The price of the market is often tied to multiple ends. First, it is related to the difficulty of preparation of this substance. If its preparation requires complex order and rare materials, the labor cost will be high, and the price will be high. If it is made with fine methods and scarce materials, the cost will increase greatly, and its price will not be cheap.
Second, it depends on the state of market supply and demand. If there are many people seeking, and there are few suppliers, it is the seller's market, and the price will rise; if the supply exceeds the demand, the seller will compete to sell, and the price may decline.
Third, it is related to the quality. The superior one can adapt to the experiments and production of high demands, and the price is often higher than that of the mediocre.
It is difficult to specify the range of its price now. However, it is roughly speculated that in an ordinary city, if there is no special situation, the price per gram may range from tens of gold to hundreds of gold due to the complexity of its structure, preparation, or the need for equivalent techniques and materials. If in a specific high-end market, there is a very strict demand for quality, the price may be more than this. However, this is just speculation. In fact, we should consult the merchants of chemical materials or explore professional trading platforms to determine the exact number.