2 Mercapto 5 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Mercapto-5-(trifluoromethyl)pyridine

    Specifications

    HS Code

    736211

    Chemical Formula C6H4F3NS
    Molecular Weight 181.16
    Appearance Solid (Typical)
    Boiling Point Approx. 215 - 220 °C
    Melting Point 48 - 52 °C
    Solubility Soluble in organic solvents like ethanol, acetone
    Density 1.44 g/cm³ (approx.)
    Vapor Pressure Low at room temperature
    Flash Point Approx. 84 °C
    Pka Approx. 3.8 (for the thiol group)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Mercapto-5-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main application fields of 2-mercapto-5- (trifluoromethyl) pyridine
    2-% hydroxyben5- (triethylmethyl) pyridine has a wide range of application fields. In the field of medicine, this compound is often the key raw material for the creation of new drugs. Because of its unique chemical structure, it can interact with specific targets in organisms, so it has great potential in the treatment and prevention of diseases. For example, it can be used to develop anti-inflammatory drugs, help the human body resist inflammation, reconcile qi and blood, and calm the viscera.
    In the field of materials science, 2-% hydroxyben5- (triethylmethyl) pyridine also has good performance. It can be used to prepare polymer materials with special properties, such as those with excellent electrical conductivity or optical properties. The materials prepared by it can be used in electronic devices to make the device run more efficiently and stably, just like injecting the smart soul into the device, so that its function can be fully exerted.
    Furthermore, in the field of agriculture, it can also play a role. It can be used as an ingredient in a new type of pesticide or plant growth regulator. As a pesticide, it can accurately kill pests and diseases, protect the growth of crops, and ensure the harvest of crops. As a plant growth regulator, it can regulate the growth cycle of plants, making the plant growth situation better and the fruit more fruitful.
    In the field of organic synthesis, this compound is often used as a key intermediate. With its structural properties, many organic compounds with complex structures and special functions can be derived. It is like the cornerstone of building an exquisite pavilion, from which, through ingenious chemical reactions, organic molecules with different shapes and unique functions can be constructed, contributing to the development of organic chemistry and promoting organic synthesis techniques to a more delicate state.
    What are the synthesis methods of 2-mercapto-5- (trifluoromethyl) pyridine?
    The synthesis method of 2-% pentyl-5- (triethyl) pyridine can be explored from the following methods according to the concept of "Tiangong Kaiji".
    First, pentanol and appropriate halogenated hydrocarbons are used as starting materials. First, pentanol is converted into halogenated pentane through a specific reaction. This process requires suitable catalysts and reaction conditions. For example, under the catalysis of sulfuric acid, pentanol is reacted with hydrogen halide to obtain halogenated pentane. Subsequently, halogenated pentane is reacted with a nucleophile containing triethyl, and the preparation of the nucleophile needs to be carefully designed. This reaction requires strict control of temperature and reaction time to improve the yield of the target product.
    Second, consider the modification of pyridine derivatives. Select a suitable pyridine precursor and introduce amyl and triethyl at a specific position. The selection of the activity check point of the pyridine precursor is extremely critical. The difference in electron cloud density at different positions on the pyridine ring can be used to introduce the corresponding groups by electrophilic substitution or nucleophilic substitution reaction. For example, the electronic effect of the nitrogen atom of the pyridine is used to guide the substituent into the desired position. During the reaction process, attention should be paid to protecting other check points that may occur on the pyridine ring to avoid side reactions.
    Third, the strategy of gradually building the carbon chain is adopted. First construct the carbon chain fragment containing amyl and triethyl, and then connect the fragment to the pyridine ring. Classical organic reactions such as Grignard reaction and Wittig reaction can be used to construct carbon chain fragments. By reacting Grignard reagents with corresponding carbonyl compounds, carbon chains can be gradually grown, and the structure and substituent positions of carbon chains can be precisely controlled. After the construction of the carbon chain fragment is completed, it is connected with the pyridine ring in a suitable reaction to realize the synthesis of 2-% pentyl-5- (triethylmethyl) pyridine.
    During the synthesis process, the purity of the raw material, the precise regulation of the reaction conditions and the inhibition of side reactions are all key elements. As described in "Tiangong Kaiwu", careful study of physical properties and delicate arrangement of procedures are required to effectively synthesize the target product.
    What are the physical and chemical properties of 2-mercapto-5- (trifluoromethyl) pyridine?
    2-% heptyl-5- (triethylmethyl) pyridine, this substance is very novel, its physical and chemical properties are unique, and it is very interesting. Let me tell you in detail for you.
    First of all, its physical properties, at room temperature, 2-% heptyl-5- (triethylmethyl) pyridine is mostly in a liquid state, with a texture like oil, and it feels warm and not greasy to the touch. Looking at its color, it is often colorless and transparent, just like water, but it is not as light as water and has a certain sticky feeling. As for the smell, it faintly exudes a special fragrance, not vulgar, but with a bit of elegant charm, which makes people feel slightly fresh. The boiling point and melting point are also fixed, and the boiling point value is quite high, indicating that a higher temperature is required to make it boil into a gaseous state; the melting point is relatively low, and it is difficult to solidify into a solid state when the common ambient temperature drops slightly.
    On its chemical properties, 2-% heptyl-5- (triethylmethyl) pyridine exhibits unique chemical activity due to the special atomic arrangement and chemical bond connection in the molecular structure. Some groups in the molecule are abnormally active and easily react with others. For example, when encountering a specific acidic substance, it can react like acid-base neutralization, and the part of the pyridine ring acts as the hub of the reaction, interacting with the hydrogen ion in the acid to change the overall chemical properties. For example, under appropriate catalysts and conditions, it can be substituted with a variety of organic reagents, in which the heptyl group and triethylmethyl group can be replaced by other suitable groups, thereby deriving many new compounds. This property is very useful in the field of organic synthesis, and can be used to synthesize many materials and drugs with unique functions. In short, 2-% heptyl-5- (triethylmethyl) pyridine has unique physical and chemical properties and has unlimited potential in many aspects of scientific research and industrial production.
    What are the precautions for 2-mercapto-5- (trifluoromethyl) pyridine during storage and transportation?
    2-% hydroxy-5- (trifluoromethyl) pyridine requires attention to many matters during storage and transportation.
    When storing it, the first environment should be selected. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, high temperature environments can easily cause chemical reactions, causing it to deteriorate or pose a safety hazard. If placed in direct sunlight or high temperature, the structure of the substance may change, affecting its quality and performance.
    When storing, the package must be sealed to prevent moisture and contact with air. This substance may react with oxygen, water vapor and other components in the air, thereby changing its chemical properties. For example, water vapor intrusion or reactions such as hydrolysis affect the purity and quality of the product. Storage should be separated from oxidants, acids, alkalis, etc., to avoid mixed storage. Due to its chemical properties, contact with these substances or cause violent reactions, causing serious accidents such as explosions and fires.
    During transportation, packaging and loading should be safe. It is necessary to ensure that the container does not leak, collapse, fall, or damage. According to the actual conditions such as the quantity and transportation distance, choose suitable packaging materials and transportation tools. If the packaging is not strong, bumps, collisions or package damage during transportation, material leakage, pollution of the environment and endangering the safety of transportation personnel.
    When transporting, you must follow the specified route and do not stop in densely populated areas and residential areas. Because of its potential danger, once an accident occurs in a crowded place, the consequences are unimaginable. Transport personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In case of emergencies such as leakage during transportation, they can be dealt with quickly and correctly to reduce the harm.
    What is the market price of 2-mercapto-5- (trifluoromethyl) pyridine?
    Wen Jun inquired about the market price of 2-hydroxy- 5- (triethylmethyl) pyridine, which is an important compound in the field of fine chemicals. However, its market price is not constant and often fluctuates with many factors.
    First, the price of raw materials has a significant impact on it. If the supply of basic raw materials required for the preparation of this compound is tight or the market price rises, the production cost will increase, which will promote the market price of the product to rise. On the contrary, if the supply of raw materials is sufficient and the price is stable, it is conducive to stabilizing the market price.
    Second, the market demand situation is also a key factor. If the downstream industry, such as medicine, pesticides, etc., has strong demand for this compound, the situation of supply exceeding demand will prompt the price to rise. If the market demand is sluggish and the product is backlogged, the price will be reduced.
    Third, the production process and technical level also affect the price. Advanced and efficient production processes can reduce production costs, enhance product competitiveness, and have more room in market pricing. If production technology lags behind and costs remain high, prices will also be relatively high.
    Fourth, factors such as the macroeconomic environment, policies and regulations should not be underestimated. The economic situation is good and the market is full of vitality, which supports product prices to a certain extent; while regulatory factors such as stricter environmental protection policies may cause some enterprises to increase environmental protection inputs, affecting production costs and output, and then affecting prices. Overall, in order to know the accurate market price of this compound, it is necessary to pay close attention to the market dynamics of chemical raw materials, changes in downstream industry demand, and also pay attention to the production and quotation information of relevant enterprises in order to have a more accurate grasp of its market price.