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What are the physical properties of 2-Mercapto-5-methoxyimizazole- (4,5-b) pyridine
2-Mercapto-5-methoxyimidazolo (4,5-b) pyridine, this is an organic compound with specific physical properties. Its appearance is often solid, but the specific color state varies depending on the purity and preparation method, or it is white to off-white powder, or it is crystalline.
When it comes to the melting point, the melting point of this compound is quite critical and can be used for identification and purity determination. However, the exact melting point varies slightly depending on the measurement conditions, and usually undergoes a phase transition within a specific temperature range. Under routine laboratory measurement conditions, the melting point may be between [X] ° C and [X + Delta X] ° C. The determination of the melting point requires precise experimental operations and can be achieved by instruments such as melting point meters.
In terms of solubility, 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine behaves differently in different solvents. In organic solvents, such as common ethanol and dichloromethane, it has a certain solubility. In ethanol, under specific temperature and concentration conditions, a certain amount can be dissolved to form a uniform solution. In water, its solubility is relatively low, and the polarity matches the water molecule poorly due to the characteristics of molecular structure. This difference in solubility is of great significance in the separation, purification and choice of reaction medium of compounds.
Furthermore, the density of the compound is also one of its physical properties. Although accurate density data requires specific experimental instruments and is affected by factors such as temperature and pressure, the approximate density range can reflect the characteristics of its relationship with other substances in terms of mass and volume. The determination of density can be carried out under specified temperature and pressure conditions with the help of instruments such as symmetry bottles.
In addition, its volatility is low, and it is not easy to evaporate from solid or liquid to gaseous under normal temperature and pressure. This property makes the compound relatively stable during storage and use, and it is not easy to be lost due to volatilization or cause safety problems. The physical properties of 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine have laid an important foundation for its application in chemical synthesis, drug development and many other fields.
What are the chemical synthesis methods of 2-Mercapto-5-methoxyimizazole- (4,5-b) pyridine
To prepare 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine, there are three methods. One is to start with 5-methoxy-2-nitropyridine, reduce to 5-methoxy-2-aminopyridine, and then co-heat with carbon disulfide and potassium hydroxide to form 2-mercapto-5-methoxy pyridine-3-thiocarboxylic acid, and then condensate with triethyl orthoformate and formamide. The raw materials are easy to obtain, but the steps are cumbersome and the yield is not ideal.
The second is to react with thiourea based on 2-chloro-5-methoxypyridine to obtain 2 - (5-methoxypyridine-2-yl) isothiourea salt first, and then cyclize it with alkali treatment to obtain the target. This method is relatively simple, but the raw material 2-chloro-5-methoxypyridine needs to be specially prepared, and the cost is slightly higher.
Third, 5-methoxypyridine-2-amine is reacted with carbon disulfide and potassium carbonate in an appropriate solvent to directly obtain 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine. This process is simple, the yield is acceptable, and the raw materials are common, which has the potential for industrial preparation. The advantages and disadvantages of each method are mutually different. When choosing a method, it depends on various factors such as the availability of raw materials, cost and yield.
What are the main application fields of 2-Mercapto-5-methoxyimizazole- (4,5-b) pyridine
2-Mercapto-5-methoxyimidazolo (4,5-b) pyridine is also a compound. Its main application fields are quite wide, in the field of medicinal chemistry, and it is often used as a key intermediate in drug development. Due to its unique chemical structure, it can interact with specific targets in organisms, so it has great potential for the creation of new drugs, such as antibacterial, antiviral, and antitumor drugs.
In the field of materials science, it has also emerged. Or it can be used to prepare functional materials, because it contains heteroatoms such as sulfur and nitrogen, giving the material special electrical, optical or chemical properties. For example, when applied to organic optoelectronic materials, it can improve the carrier transport performance and luminous efficiency of the material.
Furthermore, it also has its place in the field of agricultural chemistry. New pesticides can be developed, which can play a role in specific pests and diseases by virtue of their structural characteristics, in order to achieve the purpose of efficient prevention and control, and may have the advantages of low toxicity and environmental protection, contributing to the sustainable development of agriculture.
In addition, in analytical chemistry, it can be used as an analytical reagent for the detection and analysis of specific substances. Because it can react specifically with certain substances, qualitative and quantitative analysis of target substances can be achieved by detecting reaction products or signal changes. From this point of view, 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine has shown important application value in many fields, and it is indeed a compound worthy of further research and development.
What is the market outlook for 2-Mercapto-5-methoxyimizazole- (4,5-b) pyridine?
2-Mercapto-5-methoxyimidazolo (4,5-b) pyridine, this product has considerable market prospects today.
In today's pharmaceutical and chemical fields, many studies focus on the creation of new drug molecules. This compound has a unique chemical structure, and the structure of imidazolo-pyridine in it gives it diverse biological activity potential. At the forefront of drug research and development, researchers are constantly seeking new chemical entities with high activity, high selectivity and low toxic and side effects. 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine may meet these requirements.
In the exploration of anti-tumor drugs, its structure is highly modifiable, and it can introduce different functional groups by chemical means to fit the specific targets of tumor cells, or become a precursor compound of new anti-cancer drugs. And it also has potential in the development of drugs for the treatment of nervous system diseases. Because of its specific structure, it may interact with neurotransmitter receptors and regulate neural signaling, providing a new path for the treatment of Parkinson's disease, Alzheimer's disease and other diseases.
In the field of pesticides, this compound may have insecticidal and bactericidal activities due to its unique chemical properties. Nowadays, the demand for green and environmentally friendly pesticides is on the rise, and the development of high-efficiency, low-toxicity and environmentally friendly pesticides is the general trend. 2-Mercapto-5-methoxyimidazolo (4,5-b) pyridine may be modified by rational design to become the key component of this new type of pesticide.
Furthermore, in the field of materials science, it may be applied to organic optoelectronic materials. Due to the nitrogen and sulfur heterocyclic structure, or the unique electrical and optical properties of the material, it provides new impetus for the innovative development of organic Light Emitting Diode, solar cells and other materials.
In summary, 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine has shown broad market application prospects in many fields such as medicine, pesticides, materials, etc. It needs to be further explored, developed and utilized by researchers and industries.
2-Mercapto-5-methoxyimizazole- (4,5-b) What are the precautions in the storage and transportation of pyridine
For 2-mercapto-5-methoxyimidazolo (4,5-b) pyridine, many matters need to be paid attention to during storage and transportation.
First, this substance is quite sensitive to temperature and humidity. High temperature or cause its chemical properties to change, and even decompose and deteriorate; if the humidity is too high, it is easy to produce deliquescence, which will damage its purity and quality. Therefore, when storing, it should be placed in a cool and dry place, the temperature should be controlled in a specific range, and the humidity should not exceed the appropriate degree.
Furthermore, because of its specific chemical activity, it can come into contact with other substances or react chemically. When storing, it should not be co-located with oxidizing, reducing substances and strong acids and alkalis to avoid unexpected reactions. Packaging materials should also be carefully selected to ensure that the material does not interact with the substance, and suitable sealed packaging can be used to prevent the intrusion of external factors.
During transportation, shock protection and collision prevention are extremely critical. This substance may be damaged due to severe vibration or collision, and then exposed to the external environment, causing danger. The temperature and humidity in the transportation vehicle also need to be controlled to meet the storage requirements. And the transportation personnel should be familiar with the characteristics of this substance, and in case of emergencies, they can properly deal with it.
In addition, this substance may be toxic or irritating. No matter whether it is stored or transported, safety procedures must be strictly followed. Operators must prepare protective equipment, such as gloves, goggles, protective clothing, etc., to prevent contact with this object and injury. Discarded packaging and residues should not be discarded at will, and should be properly disposed of according to environmental requirements to avoid polluting the environment.