2 Isoproxypyridine 5 Boronic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-ISOPROXYPYRIDINE-5-BORONIC ACID

    Specifications

    HS Code

    597629

    Chemical Formula C8H12BNO3
    Molecular Weight 178.00
    Appearance White to off-white solid
    Purity Typically high, e.g., 95%+
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, THF
    Melting Point 100 - 105 °C (approximate)
    Stability Stable under normal conditions, but moisture - sensitive

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    General Information
    Where to Buy 2-ISOPROXYPYRIDINE-5-BORONIC ACID in China?
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    Frequently Asked Questions

    As a leading 2-ISOPROXYPYRIDINE-5-BORONIC ACID supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-isopropoxypyridine-5-boronic acid?
    2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8, this is an important organic compound with a wide range of uses.
    First, it has significant uses in the field of medicine. It can be used as a key raw material for the synthesis of many drugs. Because the compound has a specific chemical structure and activity, it can participate in the construction of drug molecules and play an indispensable role in the efficacy of drugs. Many drugs for the treatment of specific diseases, in the synthesis process, 2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8 often used as starting materials or key intermediates, through a series of chemical reactions, and finally converted into drug molecules with therapeutic effect.
    Second, it also has extraordinary performance in the field of materials science. It can be used to prepare materials with special properties. Because of its unique chemical properties, it can react with other substances, thus giving the material specific properties. For example, by reacting with certain polymers, the properties of polymers can be improved, such as enhancing their stability, flexibility or endowing them with special optical and electrical properties, etc., so as to meet the special requirements of different fields for material properties.
    Furthermore, in organic synthetic chemistry, it is an important synthetic building block. Organic chemists often use it to construct more complex organic molecular structures. With its own functional group characteristics, it can carry out a variety of chemical reactions, such as substitution reactions, addition reactions, etc. Through ingenious design of reaction routes, organic compounds with various structures and functions can be synthesized, providing an important material basis for the development of organic synthetic chemistry.
    In short, 2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8 plays a crucial role in many fields such as medicine, materials and organic synthesis, and promotes the continuous development and progress of related fields.
    What are the synthesis methods of 2-isopropoxypyridine-5-boronic acid?
    To prepare 2-isopropoxybenzoyl-5-bromobenzoic acid, there are various methods.
    First, starting with 2-hydroxybenzoic acid, through the bromination step, 5-bromo-2-hydroxybenzoic acid can be obtained. In a suitable solvent, add base to form a salt, and then react with isopropyl halide. Halide such as isopropyl bromide or isopropyl chloride can be introduced into isopropoxy through nucleophilic substitution to obtain the target product. This process requires attention to the reaction conditions. Temperature and the amount of alkali are all related to the effectiveness of the reaction. Excessive temperature or side reactions can be caused. Improper alkali content also affects the yield.
    Second, 2-isopropoxybenzoic acid is used as the starting material. First, it is converted into the corresponding acyl chloride. Commonly used chlorinating reagents such as dichlorosulfoxide can be reacted to obtain 2-isopropoxybenzoyl chloride. Then, in the presence of appropriate catalysts, such as iron powder or ferric chloride, bromide with bromine. Because there are isopropoxy and carboxyl groups on the benzene ring, the two have different effects on the electron cloud density of the benzene ring. During bromination, the conditions need to be controlled so that the bromine atom is mainly replaced at the 5-position, and then 2-isopropoxybenzoyl-5-bromobenzoic acid is obtained. In this approach, the preparation of acyl chloride requires an anhydrous environment, and the bromination reaction should also pay attention to the amount of bromine and the reaction temperature to avoid the formation of polybrominates.
    Third, modern organic synthesis methods such as Suzuki coupling reaction of aryl borate esters can be considered. First, aryl borate esters containing appropriate substituents and halogenated aromatics are prepared respectively, and carbon-carbon bonds are constructed by palladium-catalyzed coupling reaction, and gradually spliced into the target molecular structure. Although this method requires specific catalysts and ligands, it has good selectivity and functional group compatibility, which can effectively avoid the shortcomings of some traditional methods. If the conditions are controlled appropriately, products with higher yield and purity can be obtained.
    What are the physical properties of 2-isopropoxypyridine-5-boronic acid?
    2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E6%9C%89%E5%A6%82%E4%B8%8B%E5%88%97%E4%B8%80%E4%BA%9B:
    This acid is a colorless and transparent liquid, which is quite fluid at room temperature and pressure. Its odor is specific, slightly pungent, and uncomfortable to smell.
    When it comes to boiling point, 2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8%E7%9A%84%E6%B2%B9%E7%82%B9%E5%9C%A8%E7%9B%B8%E5%AF%B9%E4%BD%93%E5%88%86%E5%AD%A6%E5%92%8C%E5%88%86%E5%B8%83%E7%9A%84%E6%B0%A7%E5%8C%96%E7%89%A9%E4%B8%AD%E7%B3%BB%E6%95%B0%E7%9B%B8%E5%AF%B9%E4%BD%8E, about [specific value] ℃. This boiling point characteristic is very important in many chemical operations, such as distillation and separation.
    Its density is also an important physical property, heavier than water, about [specific value] g/cm ³. This density characteristic can be used in operations such as liquid-liquid separation to achieve the purpose of separation by virtue of the difference in density from other liquids.
    In terms of solubility, 2-%E5%BC%82%E4%B8%99%E6%B0%A7%E5%9F%BA%E5%90%A1%E5%95%B6-5-%E7%A1%BC%E9%85%B8%E5%8F%AF%E6%BA%B6%E4%BA%8E%E5%A4%9A%E7%A7%8D%E6%9C%89%E6%9C%BA%E5%AE%B9%E5%99%A8, such as ethanol, ether, etc., also have a certain solubility in water. This solubility provides many conveniences for its chemical reaction and material preparation process. It can be used as a reaction solvent or assist in dissolving other reactants to promote the reaction.
    In addition, the volatility of this acid cannot be ignored. Although it is not a highly volatile acid, when placed in the open, some acid molecules will escape into the air, resulting in a decrease in the concentration of the acid solution. Therefore, when stored, it needs to be properly sealed to prevent volatilization loss.
    Is the chemical properties of 2-isopropoxypyridine-5-boronic acid stable?
    2-% isobutoxyphenyl-5-thiazole carboxylic acid, this is an organic compound. To observe its chemical properties, it is necessary to observe the functional groups contained in its molecular structure.
    This compound contains a thiazole ring connected to a carboxyl group and an isobutoxyphenyl group. The carboxylic group is acidic and can dissociate hydrogen ions under appropriate conditions, showing the generality of acids, such as neutralization with bases to generate corresponding salts and water.
    The thiazole ring, as a heterocyclic structure containing nitrogen and sulfur, endows the molecule with certain stability and special electronic effects. Isobutoxyphenyl is a lipophilic group, which affects the solubility and intermolecular forces of the compound.
    In terms of stability, under normal conditions, its chemical properties are relatively stable. However, under specific conditions, such as high temperature, strong acid, strong base or the presence of specific catalysts, reactions may occur.
    In the field of organic synthesis, carboxyl groups can be converted into esters by esterification or reacted with amines to form amides. The hydrogen atom on the thiazole ring can be substituted under suitable reaction conditions, and then the molecule can be modified and derivatized.
    Due to the interaction of various groups in the molecule, 2-% isobutoxy phenyl-5-thiazole carboxylic acid can maintain stable structure and properties in most conventional environments. However, in chemical research and practical application, it is still necessary to carefully consider the changes in the reactivity and stability according to the specific reaction conditions and needs, in order to achieve the expected chemical transformation and application purposes.
    What is the price range of 2-isopropoxypyridine-5-boronic acid in the market?
    I look at the market price of "2-isopropoxyphenylboronic acid-5-bromobenzoic acid" you are inquiring about. Both are commonly used reagents in organic synthesis, and their prices vary depending on purity, manufacturer, and purchase quantity.
    First, "2-isopropoxyphenylboronic acid". If it is ordinary purity, about 97%, it can be purchased in small quantities in the market, and the price per gram may be in the tens of yuan. If you buy in large quantities, the manufacturer may have a good price due to the quantity, and the price per gram may drop to 20 yuan. However, if you want high purity, such as more than 99%, the price will increase significantly, or more than 100 yuan per gram.
    As for "5-bromobenzoic acid", if the common purity is 98%, buy it in small quantities, and the price per gram is about 20 to 40 yuan. If the quantity is large, the price per gram may drop to about 15 yuan. If its purity reaches 99% and above, the price will also rise, or to more than 50 yuan per gram.
    Intermarket prices, such as changes in the situation, sometimes rise and fall due to raw materials, supply and demand. If you want to get a definite price, you can consult the chemical reagent supplier, and he must inform you in detail.