2 Isopropyl 3 Isobutyrylpyrazolo 1 5 A Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine

    Specifications

    HS Code

    171308

    Chemical Formula C15H20N2O
    Molecular Weight 244.33 g/mol
    Physical State Solid (usually)
    Appearance Typically white to off - white powder
    Melting Point Data needed (experimental determination required)
    Boiling Point Data needed (experimental determination required)
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Value Data needed (experimental determination required)
    Flash Point Data needed (experimental determination required)

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    General Information
    Where to Buy 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine in China?
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    Frequently Asked Questions

    As a leading 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Isopropyl-3-isobutyrylpyrazolo [1,5-a] pyridine?
    2-Isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine, which is widely used. In the field of medicine, it is a key intermediate for the synthesis of many specific drugs. Due to its unique chemical structure, it can precisely combine with specific targets in organisms, helping to develop innovative therapies for specific diseases.
    In the field of materials science, this compound can be used as a synthetic raw material for functional materials. After specific chemical reactions, it endows materials with special properties such as light, electricity, magnetism, etc., showing great application potential in cutting-edge fields such as organic optoelectronic materials and sensor materials.
    In the field of agriculture, it may participate in the creation of new pesticides. With its unique mechanism of action on the physiological processes of pests, we develop high-efficiency, low-toxicity and environmentally friendly pesticide products, providing strong support for crop pest control.
    Furthermore, at the level of scientific research and exploration, as a novel organic compound, it provides rich materials and research objects for the theoretical research of organic synthetic chemistry, medicinal chemistry and other disciplines, and promotes the continuous development and progress of related disciplines to explore more novel chemical reactions and material properties.
    What are the physical properties of 2-Isopropyl-3-isobutyrylpyrazolo [1,5-a] pyridine
    2-Isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine is one of the organic compounds. Its physical properties are quite elegant, as follows:
    ** 1. Appearance properties **: This substance is often white to light yellow solid, with a fine texture. It looks like the first snow in winter, with pure and uniform color. Under sunlight, its surface glows with a soft luster, just like warm jade, showing a unique beauty. This appearance property not only reflects the characteristics of its chemical structure, but also affects its application in different fields. Due to its pure color, it is quite advantageous in some application scenarios where color requirements are strict, and can avoid adverse effects caused by color impurities.
    ** Second, melting point **: The melting point is within a specific temperature range, which is extremely critical. The determination of the melting point is like opening a window into the inner structure of the compound. As the temperature gradually rises and approaches the melting point, the intermolecular forces begin to change subtly. When the melting point is reached, the compound transitions from a solid state to a liquid state, a process that is like a magical transformation of the microscopic world. Accurate melting point data helps to identify the purity of the compound. If the melting point deviates from the established range, or implies that it contains impurities, it will affect its quality and performance.
    ** III. Solubility **: In common organic solvents, such as ethanol, acetone, etc., it exhibits a certain solubility. In the solvent environment of ethanol, it is like a fish entering water, and the molecules interact and gradually dissolve and disperse. This solubility characteristic provides convenience for its chemical operations such as synthesis, separation and purification. In organic synthesis reactions, suitable solvents can promote the full contact of reactants and accelerate the reaction process, just like building a smooth bridge for chemical reactions, so that the reactants can efficiently converge and complete wonderful chemical transformations.
    ** IV. Density **: It has a specific density value, and the density reflects the degree of tight packing of its molecules. Through the study of density, it can further understand the arrangement of its molecular structure. A higher density implies a compact arrangement of molecules and strong interaction; otherwise, it is more loose. This characteristic needs to be fully considered in practical applications, such as in the formulation design, because it may affect the stability and performance of the product.
    ** 5. Stability **: It has good stability under normal temperature and pressure and dry environment. At this time, its molecular structure is like a stable castle, and the atoms and groups cooperate with each other to resist external interference. However, if exposed to extreme conditions such as high temperature, high humidity or strong light, the stability may be challenged. High temperature may enable molecules to obtain enough energy to break the original chemical bonds and cause structural changes; in a high-humidity environment, water molecules may participate in chemical reactions, affecting their chemical properties; strong light may also stimulate electron transitions within molecules, resulting in chemical reactions. Therefore, during storage and use, it is necessary to pay attention to environmental conditions to ensure that its stability is not damaged.
    2-Isopropyl-3-isobutyrylpyrazolo the chemical properties of [1,5-a] pyridine
    2-Isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine, this is an organic compound. Its chemical properties are unique, let me tell them one by one.
    First of all, its physical properties are often solid at room temperature, due to the intermolecular forces. Its melting point and boiling point depend on the fine structure of the molecular structure. Intermolecular hydrogen bonds, van der Waals forces, etc., cause its melting and boiling point to have a specific value. However, the exact melting point and boiling point need to be accurately determined by experiments.
    At the level of chemical activity, the core structure of pyrazolopyridine in this compound gives it special reactivity. The conjugated system of the pyrazole ring and the pyridine ring makes the electron cloud distribution different, and the electrophilic substitution reaction is prone to occur at specific positions. For example, where the electron cloud density on the aromatic ring is higher, it can react with electrophilic reagents, such as halogenation, nitrification, sulfonation, etc.
    Furthermore, the 2-position isopropyl group is the power supply group, which affects the electron cloud density of the surrounding atoms by induction effect and superconjugation effect, or changes the reactivity and selectivity. The 3-position isobutyryl group, containing carbonyl, has higher reactivity. Carbon of carbonyl is positive and vulnerable to attack by nucleophiles, triggering reactions such as nucleophilic addition reactions. Common nucleophiles such as alcohols and amines can react with carbonyl groups to form corresponding acetals and amide derivatives.
    In addition, the solubility of the compound varies in different solvents. Because it contains polar groups and non-polar parts, it may have a certain solubility in polar organic solvents such as ethanol and acetone; in non-polar solvents such as n-hexane, the solubility may be limited. This solubility characteristic is crucial in the separation, purification and choice of reaction medium of the compound.
    In summary, the chemical properties of 2-isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine are determined by its structure, and various reactive activity check points and unique physical properties make it useful in organic synthesis, pharmaceutical chemistry and other fields. However, the specific properties and applications still need to be explored experimentally.
    What is the synthesis method of 2-Isopropyl-3-isobutyrylpyrazolo [1,5-a] pyridine
    The synthesis of 2-isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine is an important topic in the field of chemical synthesis. To prepare this substance, the method of organic synthesis is often followed.
    The selection of starting materials is very important, or the selection of pyrazole and pyridine derivatives with suitable substituents. First, the pyrazole ring needs to be modified to introduce isopropyl through a specific reaction. The common method is the nucleophilic substitution reaction of halopyrazole and isopropyl halide catalyzed by base. Bases such as potassium carbonate, potassium tert-butyl alcohol, etc., can promote the reaction in organic solvents such as N, N-dimethylformamide (DMF) and acetonitrile.
    The pyridine part should be tried to connect to the isobutyryl group. Or the pyridine derivative and isobutyryl halide are catalyzed by Lewis acid such as aluminum trichloride by Fu-gram acylation. This reaction can proceed smoothly in anhydrous conditions and in inert solvents such as dichloromethane.
    After the isopropyl of the pyrazole ring and the isobutyryl of the pyridine are introduced separately, the key step is to construct the thick ring structure of pyrazolo [1,5-a] pyridine. Or use a condensation reaction, such as in the presence of a suitable dehydrating agent or catalyst, to make the pyrazole interact with the pyridine derivative. The dehydrating agent can be selected from dicyclohexyl carbodiimide (DCC), etc., and the catalyst such as p-toluenesulfonic acid can promote the reaction under heating conditions to form a ring in the molecule, and finally obtain 2-isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine. After the reaction is completed, the product needs to be purified by column chromatography, recrystallization and other methods to obtain high purity target compounds.
    What is the price range of 2-Isopropyl-3-isobutyrylpyrazolo [1,5-a] pyridine in the market?
    I have not obtained the exact price range of 2-isopropyl-3-isobutyryl pyrazolo [1,5-a] pyridine in the market. However, if you want to know the price of this product, you can explore it in various ways.
    First, consult the chemical raw material supplier. The prices quoted by the suppliers may be different due to their cost considerations, purchase volume differences, market supply and demand, etc. If the purchase quantity is large, the bargaining space may be large, and the price may be more appropriate.
    Second, visit the chemical product trading platform. Such platforms gather many merchants, and there may be sales information of the product on them. You can check the price of different sellers to indicate the approximate price range. And the platform often fluctuates due to promotions and other things.
    Third, participate in chemical industry exhibitions. Here, you can face manufacturers and suppliers directly, not only can you know the product details, but also because of competition, or you can get relatively good prices.
    Fourth, consult industry experts or practitioners. They have been in this industry for a long time, are familiar with market conditions, and can give an approximate price range based on experience.
    Although the exact price is not available, following these methods, you may be able to find out the approximate price of 2-isopropyl-3-isobutyryl pyrazole [1,5-a] pyridine in the market.