As a leading 2-IODO-6-METHOXY-3-NITRO-PYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2-IODO-6-METHOXY-3-NITRO-PYRIDINE?
2-Iodine-6-methoxy-3-nitropyridine has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to synthesize various compounds with specific biological activities. In the process of drug development, its structure has been modified and transformed to generate new substances with unique pharmacological properties, or used for disease diagnosis or disease treatment.
In the field of organic synthetic chemistry, it is also an important cornerstone. Due to its unique structure, it contains different active groups such as iodine, methoxy and nitro, which can participate in many organic reactions. For example, iodine atoms can be combined with various nucleophiles through nucleophilic substitution reactions to realize the construction of carbon-carbon bonds and carbon-heteroatomic bonds, providing the possibility for the synthesis of complex organic molecules. Methoxy and nitro groups can also affect the reactivity and selectivity, adding a variety of strategies to the design of synthetic routes.
Furthermore, in the field of materials science, with the help of their reactivity, materials with special photoelectric properties can be synthesized. These materials may have potential applications in electronic devices, optical devices, etc., such as the preparation of new light-emitting materials, semiconductor materials, etc., injecting new vitality into the development of materials science.
In conclusion, 2-iodine-6-methoxy-3-nitropyridine is of great value in many scientific fields and is an important compound that promotes research and technological development in various fields.
What are the physical properties of 2-IODO-6-METHOXY-3-NITRO-PYRIDINE?
2-Iodine-6-methoxy-3-nitropyridine is a kind of organic compound. Its physical properties are particularly important for its many applications.
First of all, its appearance is often solid, because of its intermolecular forces. Its color may be yellowish to white-like, and this color characteristic is quite valuable for identification and purity judgment.
When it comes to melting point, the melting point of this compound is in a specific range, about [X] ℃. Determination of melting point is an important means to identify the substance and evaluate its purity. Due to the purity of the material, the melting point is often relatively fixed; if it contains impurities, the melting point may change and the melting range will also be widened.
In addition, its solubility also has characteristics. In common organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc., it has a certain solubility. In dichloromethane, due to its molecular structure and intermolecular force adaptation of dichloromethane, it can be moderately dissolved. This property is crucial for the extraction of organic synthesis and the selection of reaction media. However, in water, its solubility is very small, because the hydrophobic group of this compound accounts for a large proportion, and it is difficult to form an effective force with water molecules. < Br >
Its density is also an important physical parameter, about [X] g/cm ³. The value of density is indispensable in practical operations involving the measurement, storage and transportation of the substance.
In addition, the stability of the compound also needs attention. In view of its iodine, nitro and other functional groups, under certain conditions, there may be chemical reactions. If the nitro group is highly oxidizing, at a certain temperature, pH or in the presence of reducing agents, it may initiate a reaction and cause its structure to change. Therefore, when storing, it should be placed in a cool, dry and ventilated place to avoid contact with reducing substances.
The physical properties of 2-iodine-6-methoxy-3-nitropyridine play a crucial role in its application in organic synthesis, drug research and development, and provide a basic basis for related research and practice.
What is 2-IODO-6-METHOXY-3-NITRO-PYRIDINE synthesis method?
To prepare 2-iodine-6-methoxy-3-nitropyridine, the following method can be used.
First, 6-methoxy pyridine is used as the starting material, because its pyridine ring has a certain activity. First, 6-methoxy pyridine is heated with a mixed acid of nitric acid and sulfuric acid, and nitrification is carried out. In this case, sulfuric acid is used as a catalyst to promote nitric acid to produce nitroyl positive ions (NO 2O 🥰), which attack the pyridine ring. Since methoxy is an ortho-para-site group and the electron cloud density at the 3 position of the pyridine ring is relatively suitable, nitro is introduced at the 3 position of 6-methoxy pyridine to obtain 6-methoxy-3-nitropyridine. After the reaction, the product is purified by conventional separation methods such as neutralization, extraction, and distillation.
Then, 6-methoxy-3-nitropyridine is used as a substrate to react with iodine and appropriate oxidants, such as hydrogen peroxide or periodic acid, in a suitable solvent, such as glacial acetic acid. Under the action of oxidants, iodine forms an active intermediate and attacks the second position of the pyridine ring to achieve the synthesis of 2-iodine-6-methoxy-3-nitropyridine. After the reaction system is cooled, it can be filtered, washed, recrystallized and other steps to obtain a pure 2-iodine-6-methoxy-3-nitropyridine product.
Throughout the synthesis process, the reaction conditions at each step need to be carefully regulated, such as temperature, reactant ratio and reaction time, to ensure high reaction efficiency, good selectivity, and improve the yield and purity of the product.
What is the market price of 2-IODO-6-METHOXY-3-NITRO-PYRIDINE?
I think this 2 - IODO - 6 - METHOXY - 3 - NITRO - PYRIDINE is a chemical substance. However, its market price often varies due to many factors.
On the one hand, if the raw materials for synthesizing this substance are easy to obtain and affordable, the cost is controllable, and the market price may be relatively easy. On the contrary, if the raw materials are rare and hard to find, and the price is as high as pearls, the price of the finished product will be high.
Furthermore, the production process is also the key. If the process is simple and efficient, with less energy consumption and more output, the cost can be reduced and the price can be made accessible to the people. If the process is complicated, exquisite equipment and multiple operations are required, the cost will increase greatly, and the price will also rise accordingly.
The situation of market supply and demand also affects its price. If there are many people who ask for it, there will be few people who supply it, such as the clouds and clouds in a drought, and the price will rise. If there is too much production, but there are few people who need it, the price may go down like a river.
And different manufacturers, due to the advantages and disadvantages of technology and poor management, the cost is different, and the pricing is also different.
As for the exact price, it is difficult to tell. For details, you can visit the chemical product trading platform, or consult the relevant chemical distributors, where you can get real-time and accurate price information to solve your doubts.
What are the precautions in storage and transportation of 2-IODO-6-METHOXY-3-NITRO-PYRIDINE?
2-Iodine-6-methoxy-3-nitropyridine is a chemical commonly used in organic synthesis. When storing and transporting, the following numbers should be paid attention to:
First, storage. This product should be stored in a cool, dry and well-ventilated place. Because it is quite sensitive to light and heat, light and high temperature can easily cause it to chemically react and deteriorate. Therefore, it is necessary to avoid direct sunlight and keep away from heat sources. Furthermore, it should be placed in a sealed container to prevent contact with moisture, oxygen and other substances in the air. Because it contains iodine, nitro and other functional groups, water and oxygen may cause reactions such as hydrolysis and oxidation, which will affect the quality. In addition, it needs to be stored separately from oxidizing agents, reducing agents, acids, alkalis and other substances to prevent mutual reaction and cause danger. The storage area should also be equipped with suitable containment materials to deal with possible leaks.
Second, transportation. Before transportation, it is necessary to ensure that the packaging is complete and well sealed to prevent leakage during transportation. During transportation, it is necessary to follow relevant hazardous chemical transportation regulations and select transportation enterprises and transportation vehicles with corresponding qualifications. Transportation vehicles should be equipped with sun protection, rain protection, high temperature protection and other facilities to avoid direct sunlight and rain, and maintain a suitable transportation environment temperature. At the same time, transportation personnel need to undergo professional training and be familiar with the dangerous characteristics of the chemical and emergency treatment methods. In the event of a leak during transportation, immediate emergency measures should be taken, such as evacuating people, isolating the leak area, and using suitable materials for containment and cleaning. In short, the storage and transportation of 2-iodine-6-methoxy-3-nitropyridine must be treated with caution, and relevant regulations and operating procedures must be strictly followed to ensure the safety of personnel and the environment is not polluted.