2 Hydroxypyridine 4 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-hydroxypyridine-4-carboxylic acid

    Specifications

    HS Code

    231086

    Chemical Formula C6H5NO3
    Molar Mass 139.11 g/mol
    Appearance Solid
    Melting Point 220 - 222 °C
    Solubility In Water Slightly soluble
    Pka Value Around 3 - 4
    Odor Odorless (usually)
    Color White to off - white

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    General Information
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    Frequently Asked Questions

    As a leading 2-hydroxypyridine-4-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-hydroxypyridine-4-carboxylic acid?
    Alum is widely used. Of the genus alum, the common ones are alum, green alum, etc. Its main uses cover the following ends.
    One is used for medical treatment. Ancient healers often used alum as medicine. Alum is sour and cold, and has the effect of detoxification and insecticide, dryness and itching. It can be used to treat scabies, itching eczema, and long-term ulceration of sores. As the "Compendium of Materia Medica" says: "There are four uses of alum stone: to spit out the phlegm and saliva of wind and heat, to take its sour and bitter discharge; to treat all kinds of blood pain, prolapse, vulgaris, sores, to take its sour and astringent harvest; to treat phlegm drink, diarrhea, collapse, belt, wind eye, take it and dry and wet; to treat laryngeal carbuncle, snake and insect stings, to take its detoxification." Green alum also has medicinal uses, which can desiccate and reduce phlegm, eliminate accumulation and insecticide, stop bleeding and replenish blood, detoxify and reduce sores, and is often used by doctors.
    Second, used in industry. In the printing and dyeing industry, alum stone can be used as a mordant. It can make the dye better adhere to the fabric, making the dyeing more In the paper industry, it helps to size the paper, making the paper have better water resistance and improving the quality of the paper.
    Third, it is used in daily life. In terms of water purification, alum can promote the condensation and settlement of impurities in the water, so that the water can be clarified and convenient to drink. When cooking, some alum (such as potassium alum) can be used in food processing, such as frying fritters, which can make the fritters expand and crispy, but today due to health concerns, the use has gradually been restricted.
    In the field of construction, although not the main use, alum is occasionally used to participate in the preparation of special building materials to enhance some of its properties.
    As for carboxylic acids, their uses are also numerous. Carboxylic acids play an important role in the field of organic synthesis. Can be used as raw materials for the preparation of ester compounds. Esters have a pleasant aroma and are mostly used in the fragrance industry, such as ethyl acetate, which has a fruity aroma and is often used to prepare various edible flavors and daily flavors.
    Carboxylic acids can also be used to prepare amide compounds, which are widely used in chemical materials and other fields. Furthermore, in the pharmaceutical industry, many drug molecular structures contain carboxylic acid groups, whose unique chemical properties help drugs to exert their efficacy. In the food industry, some carboxylic acids are used as sour agents, such as citric acid, to give food a cool and sour taste, and have a certain antiseptic effect. They are widely used in the production of beverages, candies and other foods.
    In summary, alum and carboxylic acids have important uses in medical treatment, industry, and life, and are indispensable for human production and life.
    What are the physical properties of 2-hydroxypyridine-4-carboxylic acids?
    Valine is an essential amino acid for the human body. Its physical properties are particularly important and are related to many physiological and biochemical processes.
    Valine is in a white crystalline state at room temperature, like a fine powder, with a uniform and delicate texture. Its smell is slight, without strong pungent or special odor, and there is little significant sense of smell.
    As for solubility, valine is slightly soluble in water. When dissolved in water, the rate is relatively slow, and it takes a certain amount of stirring or a long time to disperse evenly. However, it is difficult to dissolve in organic solvents such as ethanol and ether. In these solvents, it is mostly suspended or precipitated, and does not blend with solvents.
    Valine has a certain melting point. When heated to a specific temperature, it gradually melts from solid to liquid. This melting point is an important physical indicator of it. It is between 298 and 302 ° C. It fluctuates slightly due to the slight difference in purity and test conditions.
    Furthermore, the crystal structure of valine is orderly and regular, and this structure gives it a certain stability. Under different environmental humidity, the physical properties of valine also change subtly. Moderate humidity environment has little effect on its properties; however, if the humidity is too high, it may appear to absorb moisture, and the crystal surface is slightly moist; when the humidity is extremely low, it is relatively dry, and the granularity of the crystal is more obvious. < Br >
    Looking at its density, although there is no extremely accurate value, it is relatively stable. Within a certain range, this density characteristic is also related to many physical behaviors, and it has its significance in the mixing and separation of substances. In short, the physical properties of valine lay an important foundation for its function in biological bodies and its application in chemical, pharmaceutical and other fields.
    What are the chemical properties of 2-hydroxypyridine-4-carboxylic acids
    Valine and glutamic acid are both genera of amino acids, and their chemical properties are unique.
    Valine is a non-polar aliphatic amino acid. Its side chain is isopropyl, which is hydrophobic. It is often hidden in the protein structure and maintains the stability of the three-dimensional conformation of the protein. Valine is neutral, and under general physiological conditions, its amino and carboxyl groups can be protonated and deprotonated respectively. It can participate in protein biosynthesis, encoded by specific codons, and the mRNA carries genetic information and is translated by the ribosome, so that valine is sequentially embedded in the polypeptide chain. And in metabolism, valine can be converted into corresponding α-ketoacids by transamination, entering the energy metabolism pathway and supplying energy to the body.
    As for glutamic acid, it is an acidic amino acid. The side chain contains carboxyl groups, which are acidic and hydrophilic. Under the physiological pH environment, carboxyl groups are easy to dissociate protons and carry negative charges. Glutamic acid has an extraordinary role in neurotransmission. As an excitatory neurotransmitter, it can bind to postsynaptic membrane receptors, initiate changes in membrane potential, and transmit neural signals. In terms of metabolism, glutamic acid can participate in the urea cycle, combine with ammonia to form glutamine, transport ammonia to the liver for treatment, reduce blood ammonia concentration, and maintain the body's nitrogen balance. It can also generate gamma-aminobutyric acid through decarboxylation, which is an inhibitory neurotransmitter and regulates the excitability of the nervous system. In addition, glutamic acid is also indispensable in protein synthesis and is integrated into proteins according to the rules of the genetic code.
    In summary, valine and glutamic acid have different chemical properties due to structural differences, and play diverse and key functions in living organisms.
    What are the synthesis methods of 2-hydroxypyridine-4-carboxylic acid?
    Fuvaline is one of the essential amino acids of the human body, and there are many synthesis methods. The following is the detailed description of Jun.
    First, proteolysis. In the past, this method was mostly used, using protein-rich natural products, such as hair, blood meal and waste silk, as raw materials, after acid, alkali or enzyme hydrolysis, and then separated and purified. However, this method is cumbersome, requires a lot of acid and alkali, and the purity of the product is limited, which is easy to cause pollution to the environment. Nowadays, it is less used.
    Second, fermentation method. This is the current commonly used method. Screening specific microbial strains, by adjusting fermentation conditions, such as medium composition, temperature, pH value, etc., microorganisms can synthesize valine in a large amount in a suitable environment. This method has many advantages such as low cost, high yield, and less pollution. Corynebacterium glutamicum and other strains can be selected to achieve efficient production of valine with the help of modern fermentation engineering technology.
    Third, chemical synthesis method. Valine is synthesized through organic chemical reaction. For example, isobutyraldehyde, sodium cyanide, and ammonia are used as starting materials to generate valine through a series of reactions. Although this method is theoretically feasible, the synthesis route is complex, the reaction conditions are harsh, there are many side reactions, and the product separation and purification are difficult, so the practical application is also limited.
    Fourth, enzymatic synthesis. Using the high-efficiency catalytic properties of enzymes, valine is synthesized by enzymatic reaction with specific substrates. For example, ketoacid is used as a substrate, and under the action of transaminase, it reacts with ammonia to produce valine. Enzymatic synthesis has strong specificity and mild reaction conditions, so the preparation cost of enzymes is high, limiting its large-scale application.
    All these, fermentation methods dominate the synthesis of valine due to their many advantages, but each method has its own advantages and disadvantages, and can be used according to actual needs and conditions.
    What is the price range of 2-hydroxypyridine-4-carboxylic acid in the market?
    In today's market, the price of germanium-based to its and gallium acid often varies with time and supply and demand.
    Germanium, a rare metal, has a wide range of uses and is indispensable in electronics, optics, semiconductor and other industries. In the past, its price may have fluctuated from time to time due to the abundance of minerals and the simplicity of the process. In recent years, science and technology have advanced, and its use in high-tech fields has increased, resulting in an increase in demand. However, the mining of minerals is also regulated, and the supply may be constrained. Overall, the price of germanium varies from thousands to thousands of yuan per kilogram, depending on the grade and market conditions.
    Gallium acid is also an important chemical raw material, which is useful in electronics, medicine, materials and other industries. The change in its price is also related to supply and demand and manufacturing costs. The mining and refining of minerals, the difficulty of the process, all affect the price. Roughly speaking, the price of gallium acid, per kilogram or in the range of hundreds to thousands of yuan, is subject to changes in the market conditions, and the price is also changeable.
    The city is unstable, and the price is indeterminate. The price of germanium and gallium acid depends on various factors such as mineral storage, mining and refining techniques, supply and demand conditions, and government regulations. Businesses and businesspeople need to keep an eye on changes in the market and decide business strategies in response to current needs.