2-Hydroxypyridine-3-carboxylic acid

2-Hydroxypyridine-3-carboxylic acid is one of the organic compounds. It has many unique chemical properties.
This compound contains carboxyl and hydroxyl groups, so it is acidic. The carboxyl group can dissociate hydrogen ions, and can neutralize with bases under specific conditions to form corresponding carboxylic salts and water. For example, when reacted with sodium hydroxide, 2-hydroxypyridine-3-carboxylate can be formed with water.
Hydroxyl groups also participate in many reactions. It can be oxidized and can be converted into other functional groups such as carbonyl groups under the action of suitable oxidants. At the same time, hydrogen atoms in hydroxyl groups have certain activities and can participate in substitution reactions, such as reacting with halogenated hydrocarbons to form ether compounds. < Br >
The structure of the pyridine ring of 2-hydroxypyridine-3-carboxylic acid endows it with certain aromaticity. This structure makes the compound relatively stable, and the nitrogen atom on the pyridine ring can be used as an electron donor to participate in the coordination reaction and form complexes with metal ions.
In the field of organic synthesis, because it contains a variety of active functional groups, it is often used as a key intermediate. Its structure can be modified and derived through a series of reactions to prepare organic compounds with special properties and uses, which have potential application value in pharmaceutical chemistry, materials science and other fields.
Furthermore, the solubility of the compound is affected by its functional groups. The hydrophilicity of carboxyl and hydroxyl groups makes them soluble in water, but because the pyridine ring is a hydrophobic structure, the overall solubility is also restricted to a certain extent, and the solubility in organic solvents varies depending on the properties of the solvent.

2-Hydroxypyridine-3-carboxylic acid, which has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Because of its specific chemical structure and activity, this compound can participate in the construction of drug molecules and help to develop new therapeutic drugs. For example, some drugs with antibacterial and anti-inflammatory effects are often synthesized with 2-hydroxypyridine-3-carboxylic acid as the starting material, and through a series of chemical reactions, the molecular structure of the drug is shaped to meet the therapeutic needs.
In the field of materials science, it also has unique uses. It can be used as a modifier or additive for functional materials. Due to its own active groups such as hydroxyl and carboxyl groups, it can chemically react or physically interact with other materials to improve material properties. For example, adding to polymer materials can enhance the hydrophilicity and stability of the material, or endow the material with special optical and electrical properties, meeting the diverse requirements of material properties in different application scenarios.
Furthermore, in the field of organic synthesis, 2-hydroxypyridine-3-carboxylic acids are important building blocks for building complex organic molecules. Organic chemists use their structural characteristics to cleverly connect them with other organic compounds through various organic reactions, such as esterification and amidation, to construct organic molecules with diverse structures and functions, providing rich options and possibilities for the development of organic synthetic chemistry, and promoting the creation of new compounds and the progress of organic synthesis methodologies.

The synthesis methods of 2-hydroxypyridine-3-carboxylic acid have been used in ancient times, and there are various methods, each has its own strengths, and also has its own applicability.
First, using pyridine as the initial raw material, carboxyl and hydroxyl groups are introduced into the pyridine ring through a specific substitution reaction. This process requires careful control of reaction conditions, such as temperature, pH, and the ratio of reactants. Due to the activity of the pyridine ring and the distribution of electron clouds, the reaction conditions are slightly deviated, and it is easy to form by-products, which affects the yield and purity of the target product. For example, excessive temperature may trigger excessive substitution or ring cleavage; improper pH may make the reaction difficult to proceed smoothly, or lead to product structure variation.
Second, it can be started from the relevant pyridine derivatives. First, the specific functional groups of the derivatives are modified and transformed, and the desired 2-hydroxypyridine-3-carboxylic acid structure is gradually constructed. The key to this path lies in the precise control of the selection of derivatives and the conversion of functional groups. Reasonable planning of reaction steps and conditions is required according to the inherent structure and activity of the derivatives. If the derivative is improperly selected or the conversion conditions of functional groups do not match, the synthesis route may be in trouble and the desired target product cannot be achieved.
Third, some special chemical reaction strategies can also be used, such as cyclization reaction. The appropriate chain compound is selected, and the reaction steps are cleverly designed to cyclize it under specific conditions to generate a pyridine ring, and the hydroxyl and carboxyl groups are introduced at the appropriate position. This method requires a high understanding and control of the reaction mechanism. It is necessary to precisely adjust the reaction parameters in order to promote the cyclization of the chain compound in the expected way and ensure the correct introduction of hydroxyl and carboxyl groups. Otherwise, cyclization may generate non-target pyridine ring structures, or the positions and quantities of hydroxyl and carboxyl groups do not match the requirements.
All the above synthesis methods require the experimenter to have profound chemical knowledge and rich practical experience, be careful and meticulous in the operation process, and monitor and regulate each step of the reaction in detail, in order to effectively improve the synthesis efficiency and quality of 2-hydroxypyridine-3-carboxylic acid.

I think what you are asking is that 2-hydroxypyridine-3-carboxylic acid is in the market price range. However, the price of this product often changes for many reasons, and it is difficult to say exactly.
First, the cost of production, the price of raw materials, the preparation method and the required energy consumption are all affected. If the raw materials are rare, the preparation technique is complicated, and the energy consumption is huge, the price must be high. Second, the supply and demand of the market, if there are many people who want it, and there are few producers, the price will rise; if the supply exceeds the demand, the price may fall. Third, the quality is good or bad, high purity and high quality, the price is often higher than that of ordinary people. Fourth, the supplier is also related to the place of transaction, and the price may be different from different merchants and different regions.
Based on past market conditions, the price may range from tens to hundreds of yuan per kilogram. However, this is only a rough idea, and the market is fickle. If you want to know the exact price, you should consult chemical raw material suppliers, chemical trading platforms or people in related industries. They can tell you the exact price according to the current situation.

2-Hydroxypyridine-3-carboxylic acid, this is an organic compound. Its storage conditions are very critical, which is related to the stability and quality of the substance.
According to the ancient books and many local experiences, this compound should be stored in a cool, dry and well-ventilated place. If it is cool, it is easy to cause chemical reactions or change the molecular structure due to high temperature, which will damage its inherent properties. Generally speaking, the storage temperature should be controlled between 15 ° C and 25 ° C. This temperature range can ensure its relatively stable chemical properties.
A dry environment is also indispensable. The water vapor in the air, or the interaction with 2-hydroxypyridine-3-carboxylic acid, initiates reactions such as hydrolysis, which in turn affects its purity and quality. Therefore, when storing, when using a desiccant to maintain dryness, the humidity should be kept between 40% and 60%.
Furthermore, good ventilation can avoid local accumulation of volatile gases, reduce safety risks, and help maintain the stability of the storage environment.
In addition, 2-hydroxypyridine-3-carboxylic acid is sensitive to light, and strong light irradiation may cause it to undergo photochemical reactions and cause it to deteriorate. When storing, it should be placed in a dark container such as a brown bottle to avoid light exposure. When
is stored, it should also be stored separately from oxidants, acids, bases and other substances. Due to its active chemical properties, contact with the above substances may cause violent chemical reactions, endangering safety. And the storage area should be equipped with suitable containment materials to prevent leakage accidents from being handled in time. In this way, 2-hydroxypyridine-3-carboxylic acid can be properly stored to ensure its quality and safety.