2-Hydroxypyridine-3-carbonitrile

2-Hydroxypyridine-3-formonitrile, this is an organic compound. Its main use is quite extensive. In the field of medicinal chemistry, it is often used as a key intermediate for the synthesis of various biologically active compounds. For example, it can be converted into drug molecules that have therapeutic effects on specific diseases through specific chemical reactions, providing an important cornerstone for pharmaceutical research and development.
In the field of materials science, it also has important functions. Or it can participate in the preparation of materials with special properties, such as some functional polymer materials. With its unique chemical structure, it endows materials with specific properties such as stability and optical properties, thereby expanding the application range of materials.
In the field of organic synthesis, 2-hydroxypyridine-3-formonitrile can participate in a variety of reactions and realize the construction of complex organic molecules by virtue of its own activity check point. Chemists can design clever synthesis routes according to its structural characteristics, prepare various novel organic compounds, and promote the development of organic synthetic chemistry.
In addition, in the field of pesticide chemistry, it may also have applications. Or it can be used as a raw material to synthesize pesticide products with insecticidal and bactericidal effects, contributing to the pest control of agricultural production. In short, 2-hydroxypyridine-3-formonitrile plays an important role in many chemical-related fields and plays an indispensable role in the development of various fields.

The synthesis method of 2-hydroxypyridine-3-formonitrile has been investigated by many predecessors, and is described in detail as follows.
First, pyridine is used as the starting material. First, the pyridine is appropriately modified and a specific substituent is introduced. After halogenation, halogen atoms are introduced at suitable positions in the pyridine ring. This step requires fine control of the reaction conditions, because the position selectivity of halogenation is crucial. Then through cyanation, the halogen atom is replaced by cyanide, and the cyanide group is introduced. Then through hydroxylation, hydroxyl groups are introduced at specific positions to obtain the target product 2-hydroxypyridine-3-formonitrile. Although the steps of this path are clear, the reaction conditions of each step are harsh, and parameters such as temperature and reagent ratio need to be precisely regulated.
Second, start from nitrogen-containing heterocyclic compounds. For example, select heterocyclic rings with similar structures, and construct pyridine ring structures through ring-opening and ring-closing reactions. In the process of constructing pyridine rings, cyanyl and hydroxyl groups are introduced simultaneously. This method requires in-depth understanding of the mechanism of heterocyclic ring-opening and ring-closing reactions, and clever design of the reaction process, in order to accurately introduce each group into the target position.
Third, the synthesis is catalyzed by transition metals. Using suitable organometallic reagents as catalysts, each group is gradually introduced under mild conditions. Transition metals can effectively activate the substrate molecules, promote the reaction, and improve the selectivity and yield of the reaction. However, transition metal catalysts are expensive, and the separation and recovery of the catalyst after the reaction requires fine operation.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively weigh the specific needs, raw material availability, cost considerations and other factors to choose the optimal path to efficiently synthesize 2-hydroxypyridine-3-formonitrile.

2-Hydroxypyridine-3-formonitrile is an important compound in organic chemistry. This compound has many unique physical properties and has important applications in scientific research and industry.
When it comes to appearance, 2-Hydroxypyridine-3-formonitrile is usually in the form of a white-like to light-yellow crystalline powder with a fine texture. This form is convenient for its storage, transportation and subsequent processing. Looking at its color, it is white-like to light-yellow, reflecting its chemical structure and purity. Generally speaking, the color of high purity is closer to white, and the presence of impurities or the color is slightly darker.
Melting point is a key indicator for measuring the physical properties of substances. The melting point of 2-hydroxypyridine-3-formonitrile is quite high, about 200-210 ° C. The high melting point implies strong intermolecular forces and stable structure. This property allows the compound to maintain a solid state under high temperature environments, which is advantageous for applications where heat-resistant materials are required.
Solubility is also an important physical property. 2-hydroxypyridine-3-formonitrile is slightly soluble in water, but soluble in common organic solvents such as ethanol, dichloromethane, N, N-dimethylformamide, etc. Its solubility in organic solvents provides great convenience for organic synthesis. In an organic reaction, a suitable organic solvent can be selected to dissolve the compound according to the reaction requirements to promote the smooth progress of the reaction.
In addition, the density and stability of 2-hydroxypyridine-3-formonitrile are also worthy of attention. Its density is moderate, and the specific value varies depending on the measurement conditions. In terms of stability, under normal temperature and pressure, the compound is quite stable and is not prone to chemical reactions on its own. However, under specific conditions, such as high temperature, strong acid, and strong alkali environment, its structure may change and participate in various chemical reactions.
In summary, the physical properties of 2-hydroxypyridine-3-formonitrile, such as appearance, melting point, solubility, density and stability, together determine its application in organic synthesis, drug development, materials science and other fields. According to these properties, researchers can rationally design experiments, develop new compounds and materials, and promote the development of related fields.

2-Hydroxypyridine-3-formonitrile, this is an organic compound. Its chemical properties are unique and it has a variety of reactive activities.
First, the hydroxyl group is an active functional group and can participate in many reactions. It can exhibit acidity, because the hydrogen atoms in the hydroxyl group can be dissociated under suitable conditions, and neutralize with the base to generate the corresponding salt. In the esterification reaction, the hydroxyl group can react with an acid anhydride or an acid chloride to form an ester compound. For example, when reacted with acetic anhydride, a corresponding ester will be formed. This reaction requires a suitable catalyst and reaction conditions to promote the reaction forward.
Furthermore, the cyanyl group is active. Cyanyl groups can undergo hydrolysis and gradually convert into carboxyl groups under acidic or alkaline conditions. Hydrolysis under acidic conditions, Mr. Amide, and then converted to carboxylic acid; hydrolysis under basic conditions, the process is similar, but the product is carboxylate, after acidification can obtain carboxylic acid. Cyanyl groups can also participate in nucleophilic addition reactions, such as reacting with Grignard reagents to generate nitrogen-containing complex organic compounds, providing a variety of paths for organic synthesis.
In addition, the pyridine ring endows the compound with special electronic effects and spatial structure. Pyridine rings have certain aromatic properties and can participate in electrophilic substitution reactions, although the activity is slightly lower than that of benzene rings. Substitution reactions usually occur at higher electron cloud densities in the pyridine ring, which is determined by the electron-withdrawing action of nitrogen atoms on the pyridine ring.
2-Hydroxypyridine-3-formonitrile is rich in chemical properties due to the presence of hydroxyl, cyano and pyridine rings, and has important application value in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate for the synthesis of organic compounds and drug molecules with diverse structures.

I look at you and ask "What is the price range of 2 - Hydroxypyridine - 3 - carbonitrile in the market". However, the price of this compound often varies due to various factors, which is difficult to determine.
First, the purity of this compound has a great impact on the price. If the purity is very high, it is close to the analytical purity or higher grade, and the price is high; if the purity is slightly lower, it is used for general synthetic experiments, and the price may be slightly reduced.
Second, the amount of purchase is also the key. If a large amount of purchase is made, the merchant may give a certain discount to reduce the unit price due to small profits but quick turnover; if only a small amount is purchased to meet the needs of the laboratory trial, the unit price may be higher.
Third, supply and demand conditions determine the price. If the market demand for this compound is strong and the supply is limited, the price will rise; conversely, if the supply is sufficient and the demand is flat, the price may stabilize or even decrease.
Fourth, different suppliers have different pricing strategies. Well-known large factories, due to strict product quality control and good brand reputation, the price may be high; some small factories compete for the market, and the price may be slightly lower.
According to past market speculation, a small amount of low purity products may cost a few yuan to tens of yuan per gram; if it is high purity and purchased in large quantities, the price per gram may be reduced to a few yuan, but this is only a rough estimate. The actual price needs to be confirmed by consulting each supplier in detail.