2-Hydroxymethyl-4-(3-methoxypropoxy)-3-methylpyridine

2-Hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine is an organic compound. It is widely used in the field of medicine and is often used as a key intermediate in drug synthesis. It can be cleverly combined with other chemical substances through specific reaction steps to construct drug molecules with more complex structures and specific pharmacological activities, which in turn play an important role in the treatment of diseases.
In the field of materials science, it may be able to participate in the synthesis of polymer materials. With its unique chemical structure, it endows materials with unique properties such as good solubility, thermal stability or mechanical properties, thereby expanding the application of materials in different scenarios.
In the field of fine chemicals, this compound can also be used as a raw material for the synthesis of special chemicals. Through carefully designed chemical reactions, fine chemicals with specific functions can be prepared, such as additives for coatings, inks, fragrances and other products, helping to improve the quality and performance of products.
In addition, in the study of organic synthetic chemistry, 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine is an important starting material or reaction intermediate, providing strong support for scientists to explore novel chemical reaction paths and develop innovative synthesis methods, and promoting the continuous development of the field of organic synthetic chemistry.

The synthesis of 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine is a key research in the field of chemistry. It is described in ancient French today.
To prepare this substance, one method can be started by a compound containing a pyridine ring. First take an appropriate pyridine derivative. This derivative needs to contain a modifiable group at a specific position, such as a halogen atom or a hydroxyl group, in order to facilitate subsequent reactions.
First react this pyridine derivative with a reagent containing methoxypropoxy. This reaction is suitable for a mild alkaline environment. The strength of the base needs to be finely regulated. If it is too strong, the structure of the pyridine ring will be damaged, and if it is too weak, the reaction rate will be delayed. Common bases such as potassium carbonate and sodium carbonate can be selected. Under this reaction condition, the methoxypropoxy part of the reagent will replace the group at a specific position of the pyridine derivative to form a pyridine intermediate containing methoxypropoxy.
Then, the intermediate is subjected to hydroxymethylation. This step can be completed in the presence of a suitable catalyst using reagents such as formaldehyde. The choice of catalyst is very important, such as certain Lewis acids or specific base catalysts, which can promote the smooth introduction of hydroxymethyl groups into the target position of the pyridine ring, thereby generating 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine.
Alternatively, the pyridine ring can be methylated first, so that the pyridine ring can introduce methyl groups at the 3rd position. This methylation reaction can be achieved by using suitable methylating reagents, such as iodomethane, under the action of suitable solvents and bases. Subsequently, methoxypropoxylation and hydroxymethylation are carried out in sequence. The steps are similar to the previous method, but the order is different, or the reaction conditions and product purity are slightly different.
These synthesis methods require careful consideration of reaction conditions such as temperature, time, reagent dosage, etc., to obtain this target product, and hope that its yield and purity are ideal.

The physical and chemical properties of 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine are as follows.
Looking at its appearance, it is often colorless to light yellow liquid, uniform and transparent in texture, and has good fluidity in conventional environments. Its odor is specific, but it is not pungent and intolerable. It has a unique smell that needs to be sniffed carefully to identify.
When it comes to solubility, this substance exhibits good solubility in many organic solvents. Common organic solvents such as ethanol and acetone, when mixed with them, can quickly miscible and form a uniform solution. This property is due to the existence of suitable interactions between its molecular structure and organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc., which make it easy to blend with each other.
Boiling point and melting point are also important physical properties. Its boiling point is within a certain range under certain conditions, and the specific value varies slightly due to experimental conditions, but it is roughly within a certain range. The value of this boiling point reflects the strength of the intermolecular force. A relatively high boiling point implies that the intermolecular force is strong, and more energy needs to be input to make it change from liquid to gaseous state. As for the melting point, at a specific temperature, a substance changes from solid to liquid state. This temperature is also one of its inherent properties and is restricted by the arrangement and interaction of molecules. In terms of chemical properties, the hydroxymethyl group, methoxypropoxy group and pyridine ring structure contained in its molecule endow it with various chemical activities. The existence of the pyridine ring makes the substance have a certain alkalinity and can react with acids to form corresponding salts. The hydroxyl group in the hydroxymethyl group has active chemical properties and is easy to participate in various organic reactions such as esterification and etherification. The oxygen atom in the methoxypropoxy group can be used as an electron donor to participate in some nucleophilic reactions and interact with appropriate reactants to derive a series of compounds with different structures.
These physical and chemical properties are of crucial significance in many fields such as organic synthesis and drug development, providing a basic basis for related research and applications.

I have not heard the exact price of 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine in the market. This compound may be used in various fields of medicine and chemical industry, and its price varies according to quality, quantity, source and market conditions.
If the quantity is small, and the pursuit of high purity, the price will be high. It is time-consuming and laborious to cover and purify, and the cost will increase. And if the market is eager, the supply is small, and the price will also rise.
On the contrary, if the quantity is huge and the quality is appropriate, the price may be slightly reduced. Due to the scale of production and the dilution of costs, merchants also want to make profits by selling widely.
If you want to know the exact price, you should consult the chemical raw material supplier, reagent seller, or explore it on the chemical trading platform. It can quote an accurate price according to the current situation. And the market conditions are ever-changing, and the price varies from time to time. The inquiry should be made in a timely manner.

2-Hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine, which may be involved in the field of fine chemicals. However, it is not easy to examine its manufacturer in detail. It covers the world, there are many industry players, and the information is complicated and difficult to distinguish.
Guanfu's "Tiangong Kaiwu", although it is a great work of science and technology in ancient China, is mostly concerned with agricultural mulberry, hardware, ceramics, boats and other skills, and does not involve the production of this chemical. In today's world, science and technology are changing day by day, and the chemical industry is also scattered. There are manufacturers everywhere.
If you want to find a manufacturer of this chemical, you can find it in the chemical professional directory, online chemical trading platform, and industry exhibition. These platforms gather chemical merchants from all over the world, and the list is detailed, or you can get it.
And in the chemical industry, each factory has its own strengths, or specializes in research and development, or focuses on production. There are large factories that rely on their strong financial resources to recruit talents and develop new products; there are also small factories that uphold ingenuity, focus on quality, and stand out in sub-segments. < Br >
Although the manufacturer of 2-hydroxymethyl-4- (3-methoxypropoxy) -3-methylpyridine has not been able to do its best, according to the above route, it may gradually get what it needs. Ji Jun has a smooth journey in chemical industry, and the road to finding a factory is smooth.