2 Hydroxyl3 5 Dibromo4 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-hydroxyl3,5-dibromo4-methylpyridine

    Specifications

    HS Code

    922699

    Chemical Formula C6H5Br2NO
    Molecular Weight 266.92
    Appearance Solid (usually)
    Melting Point Data may vary, need specific experimental determination
    Boiling Point Data may vary, need specific experimental determination
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Pka Value Data may vary, need specific experimental determination
    Stability Stable under normal conditions, but avoid strong oxidizing agents
    Flash Point Data may vary, need specific experimental determination

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    General Information
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    Frequently Asked Questions

    As a leading 2-hydroxyl3,5-dibromo4-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-hydroxyl3, 5-dibromo4-methylpyridine?
    2-Hydroxy-3,5-dibromo-4-methylpyridine, this substance has a wide range of uses and is widely used in the field of medicinal chemistry.
    Because of its unique chemical structure, it can be used as a key intermediate to assist in the synthesis of various biologically active compounds. For example, when creating antibacterial drugs, through a series of chemical reactions, it may be able to derive new antibacterial ingredients, which is a good way to treat bacterial infections.
    In the field of materials science, it also has extraordinary performance. With its structural properties, it can participate in the preparation of special materials. It can improve the physical and chemical properties of materials, such as enhancing the stability and conductivity of materials, or endowing materials with specific optical properties, so that materials can emerge and play important functions in the fields of optical devices, electronic components, etc.
    Furthermore, in the field of organic synthesis, it is often used as a building block for organic synthesis. Chemists can use it as a starting material to construct complex organic molecular structures by ingeniously designing reaction routes. This is of great significance for expanding the path of organic synthesis and enriching the variety of organic compounds.
    In summary, 2-hydroxy-3,5-dibromo-4-methylpyridine has important uses in many fields such as medicine, materials, and organic synthesis, providing strong support for the development of related fields.
    What are the synthesis methods of 2-hydroxyl3, 5-dibromo4-methylpyridine
    To prepare 2-hydroxy-3,5-dibromo-4-methylpyridine, there are several common methods.
    First, the corresponding pyridine derivative can be used as the starting material and obtained through a series of reactions such as halogenation and hydroxylation. For example, take 4-methylpyridine first, use a suitable brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), under suitable reaction conditions, such as in a suitable solvent, catalyzed by a catalyst, carry out a bromination reaction, and introduce bromine atoms at positions 3 and 5 to obtain 3,5-dibromo-4-methylpyridine. Then, through the hydroxylation step, such as treatment with strong bases and other reagents, the hydroxyl group at a specific position can be substituted to obtain the target product.
    Second, other synthesis routes can also be designed. Starting from the pyridine precursor containing suitable substituents, the desired structure is constructed through multi-step transformation. Or build a pyridine ring first, introduce some substituents at the same time, and then modify each position in turn. For example, through a suitable organic synthesis reaction, such as a condensation reaction to build a pyridine ring, which contains methyl at the same time, and then undergo subsequent bromination and hydroxylation operations.
    The process of synthesis requires careful consideration of the reaction conditions of each step. Temperature, reaction time, reagent dosage, etc. all have a great impact on the reaction. If the temperature is too high during bromination, it may cause excessive bromination and other side reactions; in the hydroxylation step, the alkalinity of the reagent and the length of the reaction time will also affect the yield and purity of the product. After repeated experiments to explore and optimize the reaction conditions, 2-hydroxy-3,5-dibromo-4-methylpyridine can be prepared with high efficiency and high purity.
    What are the physical properties of 2-hydroxyl3 5-dibromo4-methylpyridine
    2-Hydroxy-3,5-dibromo-4-methylpyridine is also an organic compound. Its physical properties are quite important and are related to many chemical applications.
    In terms of its appearance, under room temperature and pressure, it is often in a solid state, mostly white to off-white crystalline powders. This color state is convenient for preliminary identification and differentiation from other substances.
    As for the melting point, it has been determined by many experiments and is within a certain range. The characteristics of the melting point are like the "personalized label" of the substance, which is very helpful for the identification of its purity. If the purity of the sample is high, the melting point is sensitive and similar to the literature value; if it contains impurities, the melting point is reduced and the melting range is widened.
    Solubility is also a key physical property. In organic solvents, such as common ethanol and acetone, 2-hydroxy-3,5-dibromo-4-methylpyridine exhibits a certain solubility. This property is of great significance in chemical synthesis and separation and purification steps. By selecting a suitable solvent, operations such as dissolution and recrystallization can be achieved to achieve the purpose of purification. In water, its solubility is relatively limited, which is related to the ratio of polar groups to non-polar parts in its molecular structure.
    In addition, the density of the compound also has a specific value. Although density is not a primary consideration in some routine experiments, it is indispensable in industrial production or fine experiments involving the precise control of material measurement and mixing ratio. Only by accurately knowing the density can the dosage be accurately calculated to ensure that the reaction proceeds as expected.
    In summary, the physical properties of 2-hydroxy-3,5-dibromo-4-methylpyridine, such as appearance, melting point, solubility and density, are interrelated and play a key role in their research and application in the field of chemistry.
    What are the chemical properties of 2-hydroxyl3, 5-dibromo4-methylpyridine
    2-Hydroxy-3,5-dibromo-4-methylpyridine is a kind of organic compound. It has many chemical properties, which are described in detail by you.
    First, the presence of hydroxyl groups (-OH) makes the compound hydrophilic to a certain extent. Hydroxyl groups can participate in the formation of hydrogen bonds, which affects their physical properties such as melting point, boiling point and solubility. Because it can form hydrogen bonds with water molecules, it can have a certain solubility in water.
    Furthermore, the structure of the pyridine ring gives this compound alkalinity. The nitrogen atom in the pyridine ring has lone pairs of electrons and can accept protons. It is weakly basic. This alkalinity allows it to react with acids to form corresponding salts.
    The bromine atom at the 3,5 position is active. Bromine atoms can participate in a variety of substitution reactions, such as nucleophilic substitution reactions. Due to its high electronegativity, the connected carbon-bromine bond has a certain polarity and is vulnerable to nucleophilic reagents. Bromine atoms can be replaced by other groups, which is an important way to construct new compounds in organic synthesis.
    In addition, although the methyl group at the 4 position is relatively stable, it also affects the properties of the compound. Methyl is an electron-supplying group, which can increase the electron cloud density of the pyridine ring through induction effects, thereby affecting the reactivity of other groups on the ring.
    In chemical reactions, 2-hydroxy-3,5-dibromo-4-methylpyridine can be used as a key intermediate. Its hydroxyl groups can undergo esterification, etherification and other reactions; bromine atoms can be replaced by nucleophiles to introduce different functional groups and construct complex organic molecular structures, which are widely used in the field of organic synthesis.
    2-Hydroxyl3, what is the price range of 5-dibromo4-methylpyridine in the market?
    I look at the "2-hydroxyl3% 2C5 - dibromo4 - methylpyridine" you are inquiring about. This product is in the market price range, which is difficult to determine. Due to changes in market conditions, the price varies with many factors.
    First, the price of raw materials has a great impact. If the price of raw materials required for its synthesis rises and falls due to the time of day, place of origin, and supply and demand, the price of "2-hydroxyl3% 2C5 - dibromo4 - methylpyridine" also fluctuates.
    Second, the method of preparation is also important. If there is a new and ingenious method that can save man-hours and reduce costs, the price may be low; on the contrary, if the preparation is difficult, exquisite craftsmanship and expensive instruments are required, and the price will be high.
    Third, the market supply and demand trend determines the price. If there are many people who want it, but there are few products, the price will increase; if the supply exceeds the demand, the price will decrease.
    Fourth, the quality level is also the key. Those with high purity and excellent quality are expensive; and those with slightly inferior quality, the price may be low.
    Then I checked "Tiangong Kaiwu", but I didn't get the exact price range of this item. And today's market is very different from ancient times, and it is difficult to judge the current price according to ancient practices. Although you can't specify the price range, you can consult the chemical raw material market, relevant trading platforms, or ask the industry, and you can get a near-real price.