2-Hydroxy-5-formylpyridine

2-Hydroxy-5-formylpyridine, an important organic compound, is widely used in various fields.
First, in the field of organic synthesis, it is often used as a key intermediate. Because it has both hydroxyl and formyl groups, which are extremely active functional groups, the two can participate in various chemical reactions. Such as hydroxyl groups can undergo esterification, etherification and other reactions, while formyl groups can undergo condensation and reduction. With these reactions, 2-hydroxy-5-formylpyridine can be used to construct complex organic molecules, which lay the foundation for the synthesis of new drugs, natural products and functional materials.
Second, in the field of medicinal chemistry, its importance cannot be underestimated. Due to its unique structure, it can be modified and modified to meet the needs of specific drug targets. Studies have shown that compounds containing this structure may have certain biological activities, such as antibacterial, anti-inflammatory, and anti-tumor activities, so they have great potential to become lead compounds for the development of new drugs.
Third, in the field of materials science, 2-hydroxy-5-formylpyridine can also play a role. It can be used to coordinate with metal ions to prepare metal-organic complex materials. Such materials may have unique optical, electrical and magnetic properties, and show application prospects in luminescent materials, sensor materials, etc.
In summary, 2-hydroxy-5-formylpyridine, with its unique structure and active reactivity, plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, and materials science, promoting the development and progress of various fields.

2-Hydroxy-5-formylpyridine is one of the organic compounds. Its physical properties are worth exploring.
In terms of its appearance, it is often in a solid state. Due to the intermolecular forces, it has a specific condensed state at room temperature and pressure. As for the color, or white to light yellow powder or crystalline form, the formation of this color is related to the electronic transition characteristics in the molecular structure.
Melting point is also an important physical property. The exact value of its melting point varies slightly due to the amount of impurities contained and the difference in measurement conditions, but the approximate range can be measured. The existence of the melting point is due to the increase of kinetic energy when the molecule is heated. When it reaches a certain temperature, the lattice structure disintegrates and the solid state turns to a liquid state.
In terms of solubility, it exhibits certain solubility in organic solvents such as ethanol and dichloromethane. This is because the compound molecule and the organic solvent molecule can form interactions such as hydrogen bonds and van der Waals forces to make them mutually soluble. However, in water, the solubility is relatively limited, due to the poor matching of molecular polarity with water molecule polarity.
In terms of volatility, 2-hydroxy-5-formylpyridine has lower volatility. Due to the strong intermolecular force, molecules need to overcome a large energy barrier to break away from the liquid phase and enter the gas phase, so the volatilization is not very significant at room temperature.
In addition, the compound has certain stability and can maintain the structure unchanged under common conditions. In case of extreme conditions such as strong acid, strong base or high temperature, the molecular structure may change, leading to changes in physical properties.
In summary, the physical properties of 2-hydroxy-5-formylpyridine are determined by its molecular structure and vary slightly under different conditions. These properties are of great significance in the fields of organic synthesis, drug research and development, and are the basis for related research and applications.

The synthesis method of 2-hydroxy-5-formylpyridine has been known for a long time. One method is to use pyridine as the base, introduce the appropriate group at the specific position of the pyridine ring first, and then perform various operations such as oxidation and functional group conversion. Initially, pyridine is taken with a suitable halogenating agent, such as hydrogen halide catalyzed by iron halide, and reacts under specific temperature and pressure conditions to make the halogen atom replace the hydrogen on the pyridine ring. This step requires precise temperature control and regular stirring to ensure that the reaction proceeds in the desired direction.
Then, using the halogenated pyridine as the substrate, it reacts with metal-organic reagents with specific activities, such as Grignard reagent, in an anhydrous and oxygen-free inert environment to form carbon-carbon bonds and introduce the required carbon chain fragments. This process requires strict reaction environment, and no water vapor or oxygen should be mixed in, otherwise the reaction is prone to failure.
Then through the oxidation step, a suitable oxidizing agent, such as mild manganese dioxide or potassium dichromate with strong oxidation power, is selected. According to the characteristics of the substrate and the reaction requirements, the introduced carbon chain is partially oxidized to an aldehyde group. At the same time, there are also many ways for the introduction of hydroxyl groups, which can be achieved by nucleophilic substitution, hydrolysis and other reactions.
Another method is to chemically modify natural products containing pyridine structures or pyridine derivatives that have been synthesized as starting materials. This requires ingenious design of reaction routes according to the inherent structure of the raw materials, or the introduction of hydroxyl and formyl groups under specific conditions by taking advantage of the mild and efficient characteristics of enzymatic reactions. This process requires fine regulation of enzyme activity and reaction conditions such as pH and temperature. All synthesis methods require repeated experiments and optimization of reaction conditions in order to achieve high-efficiency and high-purity synthesis goals.

2-Hydroxy-5-formylpyridine is also an organic compound. During storage and transportation, all matters must not be ignored.
When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. This compound is afraid of heat and moisture. If it is placed in a high temperature and humid place, it may cause qualitative change. The temperature should be controlled within a specific range, and it should not be too high to prevent it from decomposing or triggering other chemical reactions.
Furthermore, the packaging must be tight. It must be contained in a sealed container to prevent the intrusion of air, water vapor and impurities. The activity of this compound is quite strong, and it is easy to change when it comes into contact with air or water vapor for a long time.
When transporting, there are also many points to pay attention to. First, anti-shock and anti-collision are the key. Due to its sensitive nature, if it is violently vibrated or collided during transportation, or the package is damaged, the compound will leak, which will cause danger. Second, the environment of the transportation tool should also be suitable. Keep it in a low temperature and dry state, and do not mix with other substances that may react.
In short, 2-hydroxy-5-formylpyridine is stored and transported, and the environment, packaging and transportation process are all related to its quality and safety. Practitioners should be cautious and follow relevant specifications to ensure safety.

I look at your question, and I am inquiring about the market price of 2-hydroxy-5-formylpyridine. However, the price of this chemical often changes due to many reasons, and it is difficult to have a fixed number.
First, the price of raw materials changes. If the starting material used to generate 2-hydroxy-5-formylpyridine, its price rises and falls, the price of the finished product also changes. If the starting material is rare, the cost is high, and its price in the market is also high; if the material is abundant and cheap, the cost decreases and the price also decreases.
Second, the supply and demand situation affects it. If the market demand for 2-hydroxy-5-formylpyridine increases sharply, but the supply is insufficient, the price will rise; on the contrary, if the supply exceeds the demand, the manufacturer will sell its goods, and the price will drop.
Third, the preparation method and technology are also involved. New and clever methods can reduce costs and increase yield, so that the price may drop; if the method is old and low efficiency, the cost is high, and the price is difficult to lower.
Fourth, the difference in regions also leads to price differences. In places with convenient transportation and industrial concentration, the price may be lower than elsewhere due to transportation costs; in remote places, the price may be slightly higher due to high logistics costs. < Br >
And different suppliers, because of their own considerations, the pricing is also different. Those who seek big profits, the price may be high; those who have plans to sell widely, the price may be close to the people. Therefore, if you want to know the exact price, you should consult the suppliers in detail and compare their quotations to know the approximate price between the markets.