2-Hydroxy-5-bromo-6-methylpyridine

2-Hydroxy-5-bromo-6-methylpyridine is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of drugs in the field of medicinal chemistry. The unique structure of the Gainpyridine ring gives it a variety of reactive activities. It can construct complex drug molecular structures through many chemical reactions, and help develop various specific drugs such as antibacterial, anti-inflammatory, and anti-tumor.
In the field of pesticide chemistry, it also plays an important role. Using it as a starting material can create high-efficiency and low-toxicity pesticides, which have significant effects on pest control and crop protection. Because it can precisely act on specific physiological targets of pests, inhibit the growth and reproduction of pests, and achieve the purpose of good insecticidal and agricultural protection.
Furthermore, in the field of materials science, 2-hydroxy-5-bromo-6-methylpyridine can participate in the synthesis of functional materials. Through clever design and reaction, materials with special optical and electrical properties can be prepared, which can be used in cutting-edge scientific and technological fields such as photoelectric display and sensors, contributing to the development of materials science.
From this perspective, 2-hydroxy-5-bromo-6-methylpyridine has key uses in many fields such as medicine, pesticides, and materials, and is of great significance to promote the progress of related industries.

2-Hydroxy-5-bromo-6-methylpyridine, which is an organic compound. Its physical properties are quite important and are related to many chemical applications.
When it comes to appearance, it is usually in a solid state, which is a common physical form. Its color is often white to light yellow, and the texture is relatively uniform. These appearance characteristics are of great reference value when initially identifying and judging its purity.
Melting point is also one of the key physical properties. Its melting point is roughly within a certain range, and the specific value varies slightly due to different preparation processes and purity. However, this melting point characteristic can be used for material identification and purity analysis. When it is heated to the melting point temperature, the substance changes from solid to liquid. This process is precise and orderly, and is valued by chemical experiments and industrial production.
Solubility is also a property that cannot be ignored. In organic solvents, such as common ethanol, acetone, etc., 2-hydroxy-5-bromo-6-methylpyridine exhibits good solubility. This property makes it more convenient to participate in the reaction in organic synthesis reactions, and as a reactant or intermediate, it can fully contact and react with other compounds. In water, its solubility is relatively weak, which is also in line with the characteristics of most such organic compounds. This difference in solubility helps to separate and purify it by extraction and other methods. < Br >
Furthermore, its density is also a specific physical parameter. Density reflects the mass of a substance per unit volume and is of great significance for the preparation of solutions and the design of reaction systems. Knowing its density can accurately calculate the amount of required substances and ensure that the reaction proceeds as expected.
The physical properties of this compound are interrelated and play an important role. They are all indispensable factors in the research and production of organic chemistry.

The synthesis method of 2-hydroxy-5-bromo-6-methylpyridine often involves several paths. First, it can be started from suitable pyridine derivatives and prepared by a series of reactions such as halogenation, hydroxylation and methylation.
First take a specific pyridine substrate, in the halogenation step, select a brominating reagent, such as liquid bromine or N-bromosuccinimide (NBS), under appropriate reaction conditions, such as heat or light, and in a suitable solvent (such as dichloromethane), the bromine atom selectively replaces a specific position of the pyridine ring to obtain 5-bromopyridine derivatives.
Then hydroxylation, with a suitable hydroxylation reagent, such as alkali metal hydroxide (such as sodium hydroxide) and a phase transfer catalyst, at an appropriate temperature and reaction time, the pyridine ring is introduced into the hydroxyl group at a specific position to obtain 2-hydroxy-5-bromopyridine derivatives.
Finally methylation, select a methylation reagent, such as iodomethane or dimethyl sulfate, under the action of a base (such as potassium carbonate), in a suitable solvent (such as acetone), the pyridine ring is introduced into the methyl group at a specific position to obtain 2-hydroxy-5-bromopyridine.
Second, it can also be synthesized by the strategy of constructing the pyridine ring. The pyridine ring is constructed by condensation and cyclization of raw materials containing suitable substituents, such as β-ketone esters, aldose and ammonia or their derivatives. During the reaction process, through the design of raw materials and the regulation of reaction conditions, the target substituents (bromine, hydroxyl, methyl) are precisely introduced into the corresponding positions of the pyridine ring to obtain 2-hydroxy-5-bromo-6-methylpyridine. The method of constructing the pyridine ring requires fine design and operation to achieve the ideal yield and selectivity.

For 2-hydroxy-5-bromo-6-methylpyridine, many matters need to be paid attention to during storage and transportation.
Its properties may be unstable, and the first environment should be stored. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. This can cause qualitative change or cause danger due to heat and moisture. Too high temperature, or cause decomposition; too high humidity, or biochemical reactions.
Furthermore, the packaging must be tight. Appropriate packaging materials should be used to ensure that it is sealed without leakage. To prevent contact with air, moisture, etc., causing damage to the ingredients. And the package should be clearly marked, clearly indicating the name of the item, characteristics, hazards, etc., for easy identification and disposal.
When transporting, also be cautious. According to its characteristics, choose the appropriate mode of transportation. Avoid mixing with oxidants, acids, alkalis, etc., to prevent violent reactions. During transportation, make sure that the container does not leak, collapse, fall, or damage. Driving should be stable to avoid bumps and vibrations, causing the package to break.
Escort personnel also need to be familiar with its characteristics and emergency treatment methods. In case of leaks and other situations, it can be handled quickly and properly to reduce hazards. And the means of transportation should be regularly inspected and maintained to ensure the safety of transportation. In this way, Fang Bao 2-hydroxy-5-bromo-6-methylpyridine is safe and sound during storage and transportation.

I do not know the exact market price range of 2-hydroxy-5-bromo-6-methylpyridine. However, the price of this compound is often influenced by a variety of factors.
One is the production scale. If large-scale production, due to the economy of scale, the unit cost may drop, resulting in lower prices; small-scale production, the cost is higher, and the price may be higher.
The second is the cost of raw materials. The synthesis of this compound requires specific raw materials, and fluctuations in the price of raw materials will affect its final selling price. If raw materials are scarce or production costs increase, the price will also rise.
The third is market demand. If the market demand for this compound is strong, the supply is in short supply, and the price may rise; if the demand is low, the supply is oversupplied, and the price may fall.
The fourth is quality and purity. High purity 2-hydroxy-5-bromo-6-methylpyridine, due to the difficulty of production and high cost, the price is often higher than that of low purity.
In addition, different suppliers have different pricing strategies, which will also cause price differences. To know the exact market price range, you can consult chemical raw material suppliers, chemical trading platforms, or check recent market survey reports to get more accurate price information.