2-Hydroxy-5-aminopyridine

2-Hydroxy-5-aminopyridine is an important category of organic compounds and is widely used in various fields.
In the field of medicinal chemistry, it is a key synthetic building block. It can be chemically modified and reacted to construct complex molecular structures with specific pharmacological activities. Based on this, many drugs for the treatment of different diseases have been developed, such as antibacterial and antiviral drugs. Because of its unique molecular structure and activity check point, it can interact with specific targets in organisms, inhibit the growth of pathogens, or regulate physiological and biochemical processes, and has remarkable results in the treatment of diseases.
In the field of materials science, 2-hydroxy-5-aminopyridine is also of great value. It can participate in the synthesis of polymer materials and endow the materials with unique properties. For example, it can be used as a functional monomer to polymerize with other monomers to prepare materials with special electrical, optical or mechanical properties. Materials modified by it may have good electrical conductivity or special fluorescence properties, making it promising for electronic devices, optical sensors, etc.
Furthermore, in the field of organic synthesis chemistry, it is often used as a reaction intermediate. With its reactivity of amino and hydroxyl groups, it can initiate a variety of chemical reactions, such as nucleophilic substitution, condensation reactions, etc. Through these reactions, chemists can build complex organic molecular structures, enrich the types and structures of organic compounds, and contribute to the development of organic synthetic chemistry.
In summary, 2-hydroxy-5-aminopyridine, with its unique chemical properties, plays an indispensable role in many fields such as medicine, materials and organic synthesis, and promotes scientific and technological progress and development in various fields.

2-Hydroxy-5-aminopyridine is one of the organic compounds. It has various physical properties, which are described in detail by you.
First of all, its appearance is often white to light yellow crystalline powder, fine and uniform, and it looks quite textured. The characterization of its color is one of the important basis for identifying this substance.
and its melting point, about 148-152 ℃. The melting point is the critical temperature at which a substance changes from solid to liquid. In this temperature range, 2-hydroxy-5-aminopyridine will undergo a phase transition, which is crucial in its separation, purification and identification.
Furthermore, its solubility. This substance is slightly soluble in water, but has good solubility in organic solvents such as ethanol and acetone. This difference in solubility is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules. The molecular structure of organic solvents such as ethanol and acetone can form a suitable interaction with 2-hydroxy-5-aminopyridine molecules, so they are soluble; while the molecular structure and force form of water have a low matching degree with 2-hydroxy-5-aminopyridine, which makes it slightly soluble in water. This solubility property can be used as an important reference for selecting solvents in chemical synthesis, separation and extraction and many other chemical operations.
In addition, 2-hydroxy-5-aminopyridine still has certain stability. Under normal temperature, pressure and without the action of special chemical reagents, its chemical structure can be maintained relatively stable, and it is not prone to spontaneous decomposition or other chemical reactions. However, in case of extreme conditions such as strong acid, strong base or high temperature, strong oxidant, its stability will be challenged, and the molecular structure may change, causing changes in chemical properties.
These are the physical properties of 2-hydroxy-5-aminopyridine, which are of great significance and value in chemical research, industrial production and other fields.

2-Hydroxy-5-aminopyridine, this is an organic compound. Its properties are both amino and hydroxyl. The amino group is basic, can form salts with acids, and is easily oxidized. The hydroxyl group has a certain acidity, can react with active metals to release hydrogen, and can also participate in esterification and other reactions.
2-hydroxy-5-aminopyridine has strong chemical activity due to the presence of this difunctional group. In nucleophilic substitution reactions, both amino and hydroxyl groups can be used as nucleophiles and react with electrophilic reagents. Due to its unique structure, it is widely used in the field of organic synthesis and can be used as key intermediates to prepare various drugs, dyes and functional materials. < Br >
In terms of solubility, due to the presence of polar groups, it may have a certain solubility in water and polar organic solvents. And because its structure contains aromatic rings, it has certain stability, but under severe conditions such as strong acid, strong base or high temperature, the structure may change.
The chemical properties of this compound are determined by its structure, and the functional groups interact with each other, giving it a variety of reactivity. It plays an important role in organic chemistry research and industrial production.

There are many ways to synthesize 2-hydroxy-5-aminopyridine. The first method is to start with 5-amino-2-chloropyridine, so that it encounters an aqueous solution of alkali, heated to carry out a hydrolysis reaction, chlorine is replaced by hydroxyl, and then 2-hydroxy-5-aminopyridine is obtained. Among them, the base can be selected from sodium hydroxide or potassium hydroxide, etc. The temperature and time of the reaction must be fine-tuned to achieve good effect. < Br >
There is another method, starting from 2,5-dichloropyridine, first using ammonia to obtain 5-amino-2-chloropyridine, and then hydrolyzing according to the previous method, and the target can also be obtained. In this process, when ammonia is hydrolyzed, the amount of ammonia, the temperature and pressure of the reaction are all factors that need to be studied and controlled in detail.
Furthermore, using 2-hydroxy-5-nitropyridine as raw material, using suitable reducing agents, such as iron and hydrochloric acid, or hydrogen plus palladium carbon, etc., to make nitro into amino groups, to obtain 2-hydroxy-5-aminopyridine. When reducing, the choice of reducing agent, dosage, and reaction conditions are all related to the quality and quantity of the product.
There are also pyridine as the starting material, through multi-step reactions, such as halogenation, nitrification, reduction, hydrolysis, etc., hydroxyl and amino groups are gradually introduced to synthesize 2-hydroxy-5-aminopyridine. Although this path is complex, it also has its own length in the selection of raw materials and the control of the reaction, and can be used according to actual conditions. All synthesis methods have their own advantages and disadvantages. Depending on the ease of availability of raw materials, the level of cost, and the purity of the product, choose the one that is good and use it.

The price of 2-hydroxy-5-aminopyridine in the market often varies depending on quality, provenance, and supply and demand conditions. Looking at the past, its price fluctuates quite a lot.
If you buy from ordinary commercial markets, the price may be between a few yuan and tens of yuan per gram. Those with excellent quality and high specifications will tend to be higher; and those purchased in bulk can often get preferential prices.
In the past market conditions, there was an occasional imbalance between supply and demand. When supply exceeds demand, the price may drop slightly; if demand exceeds supply, the price will rise. And in different places, the price is also different due to logistics and taxes.
If you want to know the exact price at the moment, you should consult a chemical material supplier, reagent bank, or visit an online chemical trading platform. The exact price can be provided there according to real-time market conditions.