2-Hydroxy-4-methylpyridine

2-Hydroxy-4-methylpyridine, which has a wide range of uses. In the field of medicine, it is often an intermediate for the synthesis of important drugs. The compound has a unique chemical structure and can be converted into a substance with specific pharmacological activities through many chemical reactions. For example, in the preparation of some antibacterial drugs, 2-hydroxy-4-methylpyridine can be used as a starting material. After a series of complex chemical modifications, it can give the final drug good antibacterial properties to fight various bacterial infections.
In the field of pesticides, it also has important functions. It can be used as a key component in the synthesis of specific pesticides. By reacting with other chemical substances, pesticides that are highly toxic to pests but have little impact on the environment can be constructed. This can not only effectively protect crops from pests, ensure food yield and quality, but also conform to the current concept of green environmental protection.
Furthermore, in the field of materials science, 2-hydroxy-4-methylpyridine also shows unique value. It can participate in the synthesis of certain functional materials, such as specific polymer materials. Because it can react with other monomers, it endows materials with special physical and chemical properties, such as improving the stability, conductivity or optical properties of materials, which opens up broad prospects for the development and application of new materials. Overall, 2-hydroxy-4-methylpyridine plays an important role in many fields such as medicine, pesticides and materials due to its various uses, promoting the development and progress of related industries.

2-Hydroxy-4-methylpyridine is also an organic compound. It has specific physical properties, which are related to its existence form, melting boiling point, solubility, etc., and is very important in the fields of chemistry.
First talk about its physical state and color. Under normal temperature and pressure, 2-hydroxy-4-methylpyridine is mostly in a solid state, and its color is white to light yellow powder. This appearance characteristic is easy to identify and initially distinguish from other substances.
As for the melting point, it is about 148-152 ° C. For the melting point, the critical temperature at which the substance changes from solid to liquid state. This characteristic is especially critical for the purification and identification of the substance. When heated to this temperature range, 2-hydroxy-4-methylpyridine melts into a liquid state, which can be separated from impurities with large differences in melting points, and is also an important basis for determining its purity.
The boiling point is also an important physical property. Its boiling point is about 267 ° C. At this temperature, the liquid 2-hydroxy-4-methylpyridine will be converted into a large amount of gas. The determination of the boiling point can help the distillation and purification of substances, and can infer the strength of intermolecular forces.
In terms of solubility, 2-hydroxy-4-methylpyridine is soluble in water, but the solubility is not very high. In polar organic solvents such as methanol, ethanol, and acetone, its solubility is better. This solubility is related to the molecular structure. The hydroxyl groups in the molecule can form hydrogen bonds with water and polar solvents to promote dissolution; however, the existence of pyridine rings and methyl groups limits their solubility in water.
In addition, 2-hydroxy-4-methylpyridine has a certain density. Although the exact value varies depending on conditions, the density is an inherent property of the substance, which is related to the relationship between its mass and volume. It is very important in chemical production and experimental operations in terms of material measurement and mixing ratio.
To sum up, the physical properties of 2-hydroxy-4-methylpyridine, such as physical state, melting point, solubility, density, etc., are of critical significance to its research, application, and the design and implementation of related chemical reactions, laying a foundation for chemists to further explore and utilize this substance.

2-Hydroxy-4-methylpyridine, this is an organic compound with many unique chemical properties.
First of all, its acidity and alkalinity. In 2-hydroxy-4-methylpyridine, the hydroxyl group can weakly ionize hydrogen ions, but the nitrogen atom of the pyridine ring has lone pair electrons, which can bind hydrogen ions, so it is both acidic and basic. In a strongly acidic environment, nitrogen atoms are easily protonated to form pyridine salt cations; in an alkaline environment, the hydrogen on the hydroxyl group can be captured to form corresponding negative ions.
Let's talk about its nucleophilicity and electrophilicity. The electron cloud on the pyridine ring is unevenly distributed, and the nitrogen atom is relatively electron-rich, showing a certain nucleophilicity, which can react with electrophilic reagents. The carbon atoms on the ring, especially the ortho and para-sites connected to the nitrogen atom, have a slightly lower electron cloud density and can interact with nucleophilic reagents.
2-hydroxy-4-methylpyridine also has active chemical reactivity. Hydroxyl groups can participate in reactions such as esterification and etherification. If they meet with acid chloride or acid anhydride, the oxygen atom of the hydroxyl group attacks the acyl carbon nucleophilically, and through a series of changes, they form ester compounds. This reaction is often used to construct ester bonds in organic synthesis.
Furthermore, its pyridine ring can undergo substitution reactions. For example, in halogenation reactions, under suitable conditions, halogen atoms can replace hydrogen atoms at specific positions on the pyridine ring. This is due to the electronic structure of the pyridine ring, which makes certain positions more active to the attack of electrophilic reagents.
In addition, 2-hydroxy-4-methylpyridine also has unique performance in some redox reactions. Both the pyridine ring and the hydroxyl group may be oxidized or reduced under specific conditions, thus transforming into different products, providing a variety of paths for organic synthesis.
This compound has rich chemical properties and is widely used in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate to prepare many compounds with special functions and biological activities.

The synthesis method of 2-hydroxy-4-methylpyridine has been investigated by many parties throughout the ages. The following is a common method.
First, 4-methylpyridine is used as the starting material and the target product can be obtained after oxidation reaction. If a suitable oxidant is used, under specific reaction conditions, hydroxyl groups can be introduced at specific positions on the pyridine ring of 4-methylpyridine to generate 2-hydroxy-4-methylpyridine. In this process, the choice of oxidant is crucial. Although strong oxidants have high reactivity, their selectivity may not be good, and they are prone to side reactions. Mild oxidants require precise regulation of reaction conditions to achieve the desired transformation.
Second, through a specific organic synthesis path, the target molecule is constructed through a series of substitutions and additions based on compounds containing pyridine structures. For example, methyl groups are introduced at the appropriate position of the pyridine ring first, and then hydroxyl groups are introduced at another position through clever reaction strategies. This path requires fine planning of reaction steps, considering the feasibility and selectivity of each step, and striving to achieve the synthesis of 2-hydroxy-4-methylpyridine in an efficient and economical way.
Third, the pyridine ring can be gradually constructed from the basic organic raw materials through multi-step reaction, and methyl and hydroxyl groups can be introduced at specific positions on the ring. Although this strategy has many reaction steps, if the reaction route can be reasonably designed, the purity and yield of the product can be effectively improved. In each step of the reaction, the reaction conditions, such as temperature, pressure, type and dosage of catalyst, need to be strictly controlled to ensure the smooth progress of the reaction and the transformation to the expected direction.
All synthesis methods have their own advantages and disadvantages. In practical application, the most suitable synthesis path should be carefully selected according to specific requirements, such as product purity, cost, and operability of reaction conditions.

I look at your question, but I am inquiring about the price range of 2-hydroxy-4-methylpyridine in the market. The price of this chemical often changes due to many reasons, and it is difficult to determine the number.
Its price may be affected by the cost of raw materials. If the cost of the starting materials required for its preparation rises and falls due to changes in weather, geographical conditions, and supply and demand, the price of 2-hydroxy-4-methylpyridine will also fluctuate. If the origin of raw materials encounters disasters, resulting in a decrease in output, a large number of applicants and a small number of suppliers, and the price of raw materials rises, the price of this chemical will also rise.
Furthermore, the production process is also key. If the process is advanced, the energy consumption is low, the yield is high, and the cost is controlled, the price may be stable and low; if the process is complicated and backward, the cost will increase greatly, and the price will also be high.
In addition, the market supply and demand situation has a great impact. If at some point, the demand for 2-hydroxy-4-methyl pyridine in many industries increases sharply, and the production and supply are difficult for a while, the price will rise; on the contrary, if the demand is low and the supply is excessive, the price will drop.
According to past market conditions and the prices of similar chemicals, the price of 2-hydroxy-4-methyl pyridine per gram may range from a few yuan to tens of yuan. However, this is only speculation, and the actual price needs to be carefully checked on the chemical product trading platform and consulted with suppliers before it can be determined. And the market conditions are changing rapidly, and the price at that time is not the price at this time, so it is necessary to inquire in real time.