2-Hydroxy-4,6-dimethylpyridine

2-Hydroxy-4,6-dimethylpyridine is one of the organic compounds. Its physical properties are quite impressive.
Looking at its properties, it mostly appears solid at room temperature. As for the color, it often appears white to light yellow. When it is pure, it is as white as snow, and if there are a little impurities, it will slightly yellowish.
When it comes to the melting point, it is about 140 ° C to 145 ° C. When the temperature rises, the substance gradually melts from a solid state to a liquid state, just like ice and snow melting when warm. This melting point characteristic is crucial when separating, purifying and identifying.
Its solubility is also characteristic. In water, it can be slightly dissolved, just like a boat on the river surface, although it is not smooth. However, organic solvents, such as ethanol, ether, acetone, etc., can be well miscible with each other, just like water and emulsion. This difference in solubility provides many conveniences for its applications in chemical and pharmaceutical fields.
As for the boiling point, it is about 260 ° C to 270 ° C. When the temperature reaches this point, the liquid is violently churned and turned into steam. This boiling point value is of great significance in distillation, concentration and other operations.
Its density is about 1.1 grams per cubic centimeter, which is slightly heavier than that of water. It is placed in water, such as a stone sinking abyss.
In addition, this substance is relatively stable in the air, but it will also react and deteriorate when exposed to strong oxidants, strong acids and alkalis, etc. Its smell is weak, although it is not pungent and unpleasant, it should be noted that excessive inhalation should not be allowed, so as not to damage health. This is also the physical properties of 2-hydroxy-4,6-dimethylpyridine.

2-Hydroxy-4,6-dimethylpyridine, this is an organic compound. Its chemical properties are unique and worthy of in-depth study.
In terms of its acidity and alkalinity, due to the presence of hydroxyl groups in the molecule, protons can be released, showing a certain degree of acidity. However, the pyridine ring is weakly basic, and the nitrogen atom has an isolated pair of electrons, which can bind to protons. Overall, its acidity and alkalinity need to be determined according to the specific environment. Under specific conditions, acidic or basic or dominant.
In terms of solubility, the compound may have a certain solubility in polar solvents such as water due to its polar hydroxyl groups. However, the molecule also contains non-polar methyl and pyridine rings, resulting in limited solubility in polar solvents, and better solubility in organic solvents such as ethanol and ether.
In terms of reactivity, the hydroxyl group is an active group and can participate in a variety of reactions. It can undergo esterification reaction and form ester compounds with acids under the action of catalysts; it can also be oxidized to form corresponding carbonyl compounds. Pyridine rings can also participate in reactions, such as electrophilic substitution reactions. Due to the uneven distribution of electron cloud density in the pyridine ring, the substitution reaction mostly occurs at specific locations.
In terms of stability, it is usually relatively stable under conditions. However, in case of strong oxidizing agents, strong acids, strong bases, etc., or the reaction may cause structural changes. At high temperature, it may also trigger reactions such as decomposition.
In summary, 2-hydroxy-4,6-dimethylpyridine is rich in chemical properties and has important applications and research value in organic synthesis, medicinal chemistry and other fields.

The common synthesis methods of 2-hydroxy-4,6-dimethylpyridine are as follows.
One is obtained by oxidation reaction with 4,6-dimethylpyridine as the starting material. In this process, a suitable oxidant needs to be selected, such as hydrogen peroxide. By the action of the oxidant, the specific position on the pyridine ring is oxidized, and the hydroxyl group is introduced at the 2 position. The key to this method is to precisely control the reaction conditions, such as temperature, reaction time, and the amount of oxidant. Excessive temperature or excessive oxidant may cause excessive oxidation, forming by-products, affecting the yield and purity of the target product.
The second is to take the corresponding halogenated pyridine derivative as the starting material and achieve it through a nucleophilic substitution reaction. First, 4,6-dimethyl halogenated pyridine containing a halogen atom in position 2 is prepared, and then it is reacted with nucleophilic reagents, such as reagents containing hydroxyl groups. This reaction needs to consider factors such as the activity of nucleophilic reagents and the choice of reaction solvents. Suitable solvents can promote the progress of the reaction, improve the reaction rate and selectivity.
Third, from some benzene series compounds with suitable substituents, a multi-step reaction can be used to construct pyridine rings and introduce hydroxyl groups and methyl groups. This approach usually involves multiple steps such as cyclization reaction and substitution reaction. Each step of the reaction needs to be carefully regulated to ensure that the reaction proceeds in the expected direction to obtain the target product. Although this method has many steps, if properly designed, it can achieve more efficient synthesis.
All these synthesis methods have their own advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity and yield requirements of the target product.

2-Hydroxy-4,6-dimethylpyridine is useful in various fields.
In the field of medicine, it can be used as a key intermediate for drug synthesis. Due to its unique chemical structure, it can participate in various reactions and help create drugs with specific curative effects. Or as an antibacterial drug, by interfering with the key metabolic pathways of bacteria, in order to achieve bacteriostatic and bactericidal effects; or for the development of drugs for the treatment of nervous system diseases, regulating the transmission of neurotransmitters, and improving diseases.
In the field of materials science, it also has extraordinary performance. It can be used to prepare functional polymer materials and endow materials with special properties. For example, the polymer chain is connected through a specific reaction to improve the stability, solubility or optical properties of the material, and it plays a role in the fields of optical devices, coatings, etc.
Furthermore, in the field of agricultural chemistry, it can be used as a raw material for pesticide synthesis. After rational design and reaction, the prepared pesticide may have high insecticidal, bactericidal or herbicidal activities, escort the growth of crops, improve yield and quality, and be environmentally friendly, with less residues.
In organic synthesis chemistry, 2-hydroxy-4,6-dimethylpyridine is an important reagent and intermediate. It can participate in many classical organic reactions, such as nucleophilic substitution, redox, etc., providing the possibility for the construction of complex organic molecular structures, enabling organic chemists to explore new compounds and expand the boundaries of organic synthesis.
Therefore, 2-hydroxy-4,6-dimethylpyridine plays an indispensable role in many fields such as medicine, materials, agriculture and organic synthesis, promoting the development and progress of various fields.

What you are asking about is the market price of 2-hydroxy-4,6-dimethylpyridine. However, this price is not static and often fluctuates due to many factors.
The first to bear the brunt is the cost of raw materials. If the price of the raw materials required for its preparation rises and falls due to changes in origin, harvest, and market supply and demand, the cost of 2-hydroxy-4,6-dimethylpyridine will be affected, which will cause its market price to fluctuate.
Furthermore, the production process is also the key. An efficient and mature process can reduce production costs and give the product a price advantage in the market; if the process is backward and the cost increases, the price will also rise.
The relationship between supply and demand in the market also affects its price. If the market has strong demand for this product and limited supply, the price will easily rise; conversely, if there is excess supply and insufficient demand, the price will tend to fall.
In addition, differences in regions also make prices different. In places with convenient transportation and developed economy, low logistics costs, fierce competition, and prices may be more accessible to the people; in remote places, due to increased costs such as transportation and storage, prices may be higher.
To know the exact market price, you can consult the chemical product trading platform, relevant distributors, or pay attention to industry information, so that you can get more accurate price information and adapt to local conditions.