2 Hydroxy 3 Iodopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-HYDROXY-3-IODOPYRIDINE

    Specifications

    HS Code

    568481

    Chemical Formula C5H4INO
    Molar Mass 207.00 g/mol
    Appearance Solid
    Color Off - white to light yellow
    Melting Point 148 - 150 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol
    Odor Odorless
    Pka 4.64
    Stability Stable under normal conditions

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    General Information
    Where to Buy 2-HYDROXY-3-IODOPYRIDINE in China?
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    Frequently Asked Questions

    As a leading 2-HYDROXY-3-IODOPYRIDINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-HYDROXY-3-IODOPYRIDINE?
    2-Hydroxy-3-iodopyridine is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
    In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. Due to its unique chemical structure, it can participate in a variety of chemical reactions to construct molecular structures with specific biological activities. Through chemical modification and transformation, it can create drugs with therapeutic effects on specific diseases. For example, in the synthesis of some antiviral and anti-tumor drugs, 2-hydroxy-3-iodopyridine can act as a starting material or a participant in the key reaction process, helping to generate active ingredients with precise pharmacological effects.
    In the field of materials science, it also has good performance. It can be used to prepare functional materials with special properties. For example, in the synthesis of some optoelectronic materials, its introduction into the molecular structure of the material can change the electron cloud distribution and optical properties of the material, so that the material exhibits unique photoelectric conversion efficiency, fluorescence emission characteristics, etc., which are applied to advanced material systems such as organic Light Emitting Diodes and solar cells.
    In the field of organic synthetic chemistry, 2-hydroxy-3-iodopyridine is used as a reaction substrate. With its reactivity of hydroxyl groups and iodine atoms, it can carry out a variety of classical organic reactions such as nucleophilic substitution and coupling. Chemists use these reactions to build complex organic molecular frameworks, expand the structural diversity of organic compounds, and provide rich strategies and approaches for the creation of new organic functional molecules.
    In summary, 2-hydroxy-3-iodopyridine, with its unique chemical properties, plays an indispensable role in many fields such as medicine, materials, and organic synthesis, promoting the continuous progress and development of related science and technology.
    What are the physical and chemical properties of 2-HYDROXY-3-IODOPYRIDINE
    2-Hydroxy-3-iodopyridine is one of the organic compounds. Its physicochemical properties are worth exploring.
    When it comes to its properties, under room temperature, it is mostly in the shape of a solid state, and the color may be white to light yellow powder, which is fine in appearance. Due to the interaction between molecules, it is stable in normal conditions and has this form.
    In terms of solubility, it is slightly soluble in organic solvents such as ethanol and dichloromethane. Due to the molecular structure of the compound, it contains hydroxyl groups and pyridine rings. Hydroxy groups have a certain hydrophilicity, but iodine atoms and pyridine rings have lipophilicity, so it has this performance in organic solvents. However, in water, its solubility is limited, and its dispersion in water is inhibited due to the lipophilic part of the overall structure. The melting point of
    is about a specific temperature range, which is determined by the intermolecular force. The hydrogen bonds and van der Waals forces between molecules make it melt at a certain temperature. This temperature is a key guide for its purification, identification and other operations.
    Stability is also an important property. Under normal environmental conditions, it is still stable. When encountering strong acids and bases, the molecular structure is easily damaged. Because hydroxyl groups can react with bases, pyridine rings will also react with strong acids, causing their chemical properties to change. Light, high temperature and other factors may also affect its stability. Under light, iodine atoms may cause luminescent chemical reactions, and high temperature may cause intramolecular chemical bond breakage.
    The physicochemical properties of 2-hydroxy-3-iodopyridine are determined by its unique molecular structure and are of key significance in many chemical application scenarios.
    What are 2-HYDROXY-3-IODOPYRIDINE synthesis methods?
    The synthesis method of 2-hydroxy-3-iodopyridine has always been an ancient method to follow. In the past, chemical experts often took pyridine as a group when synthesizing this substance, and through delicate transformation, in order to achieve the purpose.
    One method is to first make pyridine go through the step of hydroxylation. The pyridine is placed in a suitable reaction environment, and a specific hydroxylating agent is added, such as a combination of a certain type of metal salt and an oxygenated agent. Under precisely controlled temperature and pressure, hydroxyl groups can be introduced into the pyridine ring to obtain 2-hydroxy pyridine. This step requires strict control of the reaction conditions. If the temperature is too high or too low, and the proportion of reagents is out of balance, the reaction can be biased and the yield is poor.
    Then, make 2-hydroxypyridine iodide reaction. With iodine source such as iodine elemental substance or iodine compound, with suitable catalyst and solvent, under specific conditions, iodine atoms can replace hydrogen atoms at specific positions on the pyridine ring, and finally 2-hydroxy-3-iodine pyridine. However, in this process, the choice and amount of catalyst is the key, which not only affects the reaction rate, but also affects the selectivity of the product.
    Another way is to protect the pyridine ring first, mask the unwanted check point on the pyridine ring with a specific group, and then carry out hydroxylation and iodization in sequence, and then remove the protective group after completion. Although this path is a little complicated, it can effectively improve the selectivity and yield of the reaction and avoid unnecessary side reactions.
    There are also those who use pyridine derivatives as starting materials. By modifying the structure of the derivative or introducing specific functional groups, the subsequent hydroxylation and iodization are easier to carry out, and the reaction check point and product purity can be better controlled.
    All these methods require chemists to carefully observe the reaction mechanism and fine-tune the reaction conditions in order to synthesize 2-hydroxy-3-iodopyridine, and obtain ideal results.
    What is the price of 2-HYDROXY-3-IODOPYRIDINE in the market?
    In today's world, it is not easy to know the price of 2-hydroxy-3-iodopyridine on the market. The market situation is fickle, and its price varies with many factors.
    Looking at the description of "Tiangong Kaiwu" in the past, although he remembered all kinds of skills and products in detail, the chemical things at that time were not as delicate and complicated as they are today. Today's 2-hydroxy-3-iodopyridine is a product of modern chemical synthesis, and it may be difficult to find traces of its price in "Tiangong Kaiwu".
    However, considering the reasons for its price changes, the abundance of raw materials, the difficulty of synthesis, and the amount of demand are all key. If the raw materials are abundant, the synthesis method is simple, and there are few people who ask for it, the price may be inexpensive; conversely, the raw materials are scarce, the synthesis is difficult, and the number of people who need it will be high.
    If you want to know the price today, you should consult a chemical material merchant or a platform for chemical transactions to get the actual price on the market. Although "Tiangong Kaiwu" has made a great contribution to the way of production and creation in the past, it is difficult to rely on the price of modern chemical substances, and you must explore it through today's methods.
    What are 2-HYDROXY-3-IODOPYRIDINE storage conditions?
    2-Hydroxy-3-iodopyridine is one of the chemical substances. Its storage conditions are crucial, and it is related to the properties and stability of this substance.
    Cover this substance in a cool and dry place. If it is cool, it can prevent its chemical properties from changing due to excessive temperature. High temperature can often promote chemical reactions, or cause it to decompose, deteriorate, and lose its original characteristics. A dry environment is also indispensable, because moisture easily reacts with many chemicals. 2-Hydroxy-3-iodopyridine will lose its quality if it encounters water vapor or hydrolysis.
    and must be kept away from ignition sources and oxidants. The source of fire is easy to cause it to burn, and this substance may be flammable. In case of an open flame, it will be dangerous. Oxidants can also react violently with 2-hydroxy-3-iodopyridine, causing danger. When the two meet, they may cause explosions, violent combustion and other disasters.
    Store in a place with good ventilation. With good ventilation, harmful gases are difficult to aggregate. If 2-hydroxy-3-iodopyridine volatilizes harmful gases, good ventilation can make it dissipate in time without endangering the surrounding environment and personal safety.
    And it should be sealed and stored. The seal can prevent the intrusion of external air, water vapor, etc., to maintain its purity and stability. If exposed to air, contact with oxygen and other components, or slow oxidation, resulting in quality deterioration.
    When storing, it should also be clearly marked. Indicate the name, characteristics, hazards and storage precautions of this substance, so that contacts can see at a glance, operate according to regulations, and avoid accidents. In this way, 2-hydroxy-3-iodopyridine must be properly stored to ensure its safety and quality.