2-Hydrazino-5-Bromopyridine

2-Hydrazyl-5-bromopyridine is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its unique structure, it can be combined with other compounds through various chemical reactions to construct drug molecules with specific pharmacological activities.
In the field of materials science, 2-hydrazyl-5-bromopyridine also has its uses. Or can participate in the preparation of materials with special properties, such as materials with specific optical and electrical properties. The hydrazine and bromine atoms contained in its structure can cause special interactions during material synthesis, which in turn affects the overall properties of the material.
In addition, in the field of organic synthetic chemistry, 2-hydrazine-5-bromopyridine is often used as a reactant to construct more complex organic molecular structures. With its unique chemical activity, it can open up a variety of reaction pathways, enabling chemists to prepare organic compounds with novel structures and specific functions, contributing to the development of organic synthetic chemistry.

2-Hydrazinyl-5-bromopyridine is one of the organic compounds. Its physical properties are quite critical, and it is of great significance in the fields of chemical industry, pharmaceutical research and development.
First of all, its properties are mostly white to light yellow solid powder under normal conditions, which is easy to identify and handle. Looking at its color, it is white to light yellow, reflecting its purity and intrinsic structural characteristics.
The second-mentioned melting point is between 180-185 ° C. The melting point is an inherent property of the substance. This temperature range can help determine its purity. If there are many impurities, the melting point may drop and the melting range becomes wider.
Furthermore, the solubility of the compound also has characteristics. In common organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it has good solubility, which makes it easy to disperse uniformly in organic synthesis reactions and promotes the reaction. However, in polar solvents such as water, the solubility is poor, which is related to the distribution of polar groups in the molecular structure.
In addition, 2-hydrazine-5-bromopyridine has a certain stability. When encountering strong oxidizing agents, strong acids and bases, the structure may change. When storing, it should be placed in a cool, dry and well-ventilated place, protected from light and heat sources, to prevent deterioration.
In addition, its odor is weak, which has little impact on the odor of the operating environment, which is conducive to the operation of the experimenter. However, although the odor is weak, appropriate protection is still required during operation, because of its chemical properties or potential harm to the human body.
In summary, 2-hydrazine-5-bromopyridine has unique physical properties, and it is crucial to grasp these properties for its application in various fields.

The chemical synthesis method of 2-hydrazine-5-bromopyridine is as follows:
The initial material is 5-bromopyridine-2-carboxylic acid, which is co-placed with dichlorosulfoxide in a suitable reaction vessel. Heating prompts the reaction to occur. 5-bromopyridine-2-carboxylic acid and dichlorosulfoxide are acylated to obtain 5-bromopyridine-2-formyl chloride. This reaction process requires attention to the control of temperature and the monitoring of reaction time to ensure sufficient reaction. Subsequently, the obtained 5-bromopyridine-2-formyl chloride is mixed with hydrazine hydrate. The two react under appropriate conditions and undergo a series of changes such as nucleophilic substitution to generate 2-hydrazine-5-bromopyridine. During the period, attention should be paid to the influence of reaction conditions such as temperature and pH on the reaction process and product purity. After the reaction, suitable separation and purification methods, such as column chromatography, are used to obtain high-purity 2-hydrazine-5-bromopyridine.
Another synthetic route can be started from 5-bromopyridine-2-aminopyridine. First, 5-bromo-2-aminopyridine and sodium nitrite are diazotized in an acidic medium to form diazonium salts. After that, the diazonium salt is reacted with hydrazine, and the diazonyl group is replaced by hydrazine group, and 2-hydrazino-5-bromopyridine can also be prepared. In this process, the conditions of the diazotization reaction are very critical. The concentration of the acidic medium and the reaction temperature will affect the formation and stability of the diazonium salt. Subsequent reactions with hydrazine also need to consider the reaction conditions to make the reaction proceed smoothly and obtain the ideal product yield and purity.

2-Hydrazine-5-bromopyridine is a chemical substance that requires careful attention in many aspects when storing and transporting.
Its chemical properties are active and it is easy to react with a variety of substances. When storing, make sure that the container is well sealed to prevent contact with oxygen, moisture and other components in the air. Because it may react with water hydrolysis, it may also be oxidized by oxygen, which may cause deterioration. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to avoid chemical reactions caused by excessive temperature.
When transporting, choose suitable packaging materials in accordance with relevant regulations. Packaging needs to be strong enough to withstand a certain external force impact to prevent material leakage due to package damage. To strictly follow the regulations for transporting hazardous chemicals, transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment. Transportation personnel also need to be familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident, they can respond quickly and correctly.
In addition, whether it is storage or transportation, it is necessary to strictly do a good job of marking, clearly marking the name of the substance, dangerous characteristics and other key information, so that relevant personnel can accurately identify and operate. Do not mix or mix with oxidizing substances, acidic substances, etc., to prevent violent reactions and endanger safety. Overall, the storage and transportation of 2-hydrazine-5-bromopyridine must be treated with care to ensure the safety of the entire process.

I look at the "2 - Hydrazino - 5 - Bromopyridine" you are inquiring about. This is a chemical product. As for its market price range, it is difficult to determine. The cover is often disturbed by various factors because of its price.
The first to bear the brunt is the difficulty of production. If the preparation of this compound requires complicated processes and rare raw materials, the price will be high. On the contrary, if it is easier to prepare, the price may be relatively low.
Furthermore, the state of market supply and demand is also the key. If there are many people who need it and there are few people in supply, the price will rise; if there is an oversupply, the price will tend to drop.
In addition, the quality also affects the price. The price of high purity and high quality is often higher than that of ordinary ones.
In the example of "Tiangong Kaiwu", the price of various craft products is also different due to factors such as origin, process, and time demand. The same is true for "2 - Hydrazino - 5 - Bromopyridine" today, or the price varies greatly in different places and at different times. According to common sense, the price may range from a few yuan to several hundred yuan per gram, but this is only speculation. The actual price still needs to be consulted with the chemical reagent supplier in detail, subject to their real-time quotation.