2-{[(furan-2-yl)methyl]sulfanyl}pyridine

2-%7B%5B%28furan-2-yl%29methyl%5Dsulfanyl%7Dpyridine, this is the name of an organic compound. In the ancient classical Chinese style of "Tiangong Kaiwu", and its chemical structure is described in about 500 words as follows:
Looking at this 2-%7B%5B%28furan-2-yl%29methyl%5Dsulfanyl%7Dpyridine, its structure is exquisite and contains the wonders of the universe. The first view of the nucleus of pyridine, like a stable base, is a six-membered ring structure, cleverly connected by five carbon atoms and one nitrogen atom, in a planar shape, like a natural ring, the bond between the rings, or single or double, alternately arranged, both stable and active.
Then observe its side chain, using sulfur atoms as a bridge, connected to the structure of furan methyl. Furan, also a ring, five-element shape, composed of four carbon atoms and one oxygen atom, echoes the pyridine nucleus. The atoms in the furan ring, each in its place, form a unique conjugate system, with a special electron cloud distribution, which affects the overall properties of the compound.
The methyl group of the furan ring is attached to the side chain, which is like a pearl on the ring, increasing the complexity of its spatial structure. The sulfur atom acts as the hub connecting the two, and the arrangement of its outer electrons makes the electron transfer and chemical reaction activity of the compound unique.
This 2-%7B%5B%28furan-2-yl%29methyl%5Dsulfanyl%7Dpyridine, the atoms and groups in its structure interact to form an organic whole. In the field of chemistry, it may exhibit unique physical and chemical properties, such as participating in specific reactions and affecting the solubility and stability of substances. It is like the interdependence of all things in heaven and earth, and the co-evolution of wonderful chemical changes.

2-%7B%5B%28furan-2-yl%29methyl%5Dsulfanyl%7Dpyridine, this is an organic compound. Its physical properties are quite important and meaningful for scientific research and practical applications.
First, the appearance is usually solid, which is easy to store and operate. As for the color, it is mostly white or off-white, and the pure color often implies higher purity, which can reduce the interference of impurities in specific reactions.
Melting point is also a key property. Experiments have determined that its melting point is within a certain range, which is important for identifying the compound and controlling the reaction conditions. A stable melting point means that the compound has a high purity, and above the melting point, the state of matter will change, and the solid state will melt into a liquid state. This process requires the absorption of heat and the change of intermolecular forces.
In terms of solubility, it exhibits a certain solubility in specific organic solvents. In common organic solvents such as ethanol, dichloromethane, etc., it can be dissolved, which facilitates its application in organic synthesis. In solution, molecules can better contact each other, which is conducive to the reaction. However, the solubility in water is not good, because the proportion of organic groups in its structure is large, and the force between water molecules is weak.
The density of this compound also has its own characteristics. Under specific conditions, its density is relatively stable. Density data is indispensable in separation, purification and design of reaction devices, and is related to the precise ratio and operation of the reaction system.
In addition, its stability is good under certain conditions. However, when exposed to high temperature, strong light or specific chemical reagents, chemical reactions and structural changes may occur. This property reminds that environmental conditions should be paid attention to during storage and use to ensure that its chemical properties are stable and maintain its original structure and function.
In summary, the physical properties of 2-%7B%5B%28furan-2-yl%29methyl%5Dsulfanyl%7Dpyridine, from appearance, melting point, solubility, density to stability, play a key role in their research and application in the field of chemistry. Researchers need to be familiar with these properties in order to better use the compound.

2-% {[ (furan - 2 - yl) methyl] sulfanyl} pyridine, Chinese name or 2 - {[ (2 - furan) methyl] thio} pyridine, this substance is often used as a reactant in many reactions in organic synthesis.
In nucleophilic substitution reactions, the special structure of the furan ring and the pyridine ring gives it unique activity. The nitrogen atom of the pyridine ring has lone pairs of electrons, which can attract electrophilic reagents, while the furan ring is rich in electrons, and the two cooperate to make the carbon atom of the compound a nucleophilic attack target. For example, electrophilic reagents such as halogenated hydrocarbons can undergo nucleophilic substitution with 2- { (2-furanyl) methyl] thio} pyridine, introducing new functional groups to organic molecules, laying the foundation for the construction of complex organic structures.
In metal catalytic coupling reactions, 2- {[ (2-furanyl) methyl] thio} pyridine can be used as ligands. Its pyridine ring and furan ring can coordinate with metal atoms by lone pairs of electrons to form stable metal complexes. This complex exhibits high catalytic activity in catalyzing the formation of carbon-carbon bonds and carbon-heteroatomic bonds. Like Suzuki coupling reaction, Stille coupling reaction, etc., the participation of this compound can improve the reaction efficiency and selectivity, and is widely used in the field of drug synthesis and materials science, helping to create new drugs and functional materials.
In redox reactions, 2- { (2-furanyl) methyl] thio} pyridine or due to factors such as sulfur atoms in the structure participates in the electron transfer process. Sulfur atoms in variable valence states, under suitable redox conditions, undergo oxidation or reduction reactions, which in turn promote the overall reaction process, and play a key role in some complex organic synthesis reactions involving the transformation of sulfur valence states.

To prepare 2 - { (furan-2-yl) methyl] thioalkyl} pyridine, there are several feasible methods. First, the reaction of furan-2-ylmethanol with sodium hydrosulfide to obtain sodium furan-2-ylmethyl mercaptan, and then react with 2-chloropyridine. The two are in a suitable solvent, such as N, N-dimethylformamide, under the action of bases such as potassium carbonate, heated and stirred, and after nucleophilic substitution reaction, the target product can be obtained. The main point of the reaction is that the solvent needs to be anhydrous to avoid side reactions; the amount of base, when accurately controlled, will affect the purity of the product, and at least the reaction will be slow.
Second, 2-pyridyl mercaptan is reacted with halomethane, such as bromomethane or iodomethane, in the presence of a base to obtain 2-pyridyl methyl sulfide. Then furan-2-ylboronic acid and 2-pyridyl methyl sulfide are used for palladium-catalyzed coupling reaction. Commonly used palladium catalysts such as tetra (triphenylphosphine) palladium, ligands such as tri-tert-butylphosphine, in suitable bases such as cesium carbonate and solvents such as 1,4-dioxane, heated and refluxed to form targets. In this way, attention should be paid to the activity of palladium catalysts, which are easily affected by impurities, and the reaction system needs to be protected by inert gas to prevent
Or use 2-halopyridine to react directly with (furan-2-yl) methyl mercaptan. This reaction is carried out in a solvent such as acetonitrile with an appropriate base as an acid binding agent, such as triethylamine. In this process, the halogen atom activity of halopyridine affects the reaction rate. Iodopyridine has the highest activity, but the cost is also high; chloropyridine has low cost, but its reactivity is slightly inferior. The reaction conditions need to be adjusted, such as increasing the temperature and prolonging the time, to promote the complete reaction. All methods have advantages and disadvantages. When implementing, the choice should be based on factors such as the availability of raw materials, cost and product purity.

2-% {[ (furan-2-yl) methyl] sulfanyl} pyridine is an organic compound. In practical applications, it has outstanding performance in the fields of medicinal chemistry, materials science and organic synthesis.
In the field of medicinal chemistry, such compounds containing sulfur and pyridine structures often have unique biological activities. The combination of pyridine and furan rings endows them with specific spatial configurations and electronic properties, or can interact with targets in vivo, such as specific enzymes or receptors. After research, some of these compounds have exhibited antibacterial, anti-inflammatory and even anti-tumor activities. For specific pathogens, they may inhibit bacterial growth and reproduction by interfering with bacterial cell wall synthesis and metabolic processes, providing potential directions for the development of new antibacterial drugs.
In the field of materials science, 2-% {[ (furan-2-yl) methyl] sulfanyl} pyridine can be used as a key structural unit for the construction of functional materials. Due to its unique electronic structure, it may participate in the electron conduction process, and has potential applications in organic semiconductor materials. For example, it can be introduced into polymer systems or can regulate the electrical properties of materials for the preparation of optoelectronic devices such as organic Light Emitting Diodes and field-effect transistors, providing the possibility for the development of high-performance and low-cost organic electronic materials.
In the field of organic synthesis, this compound is an important synthesis intermediate. The activity check point of sulfur atom and pyridine ring and furan ring in its structure can participate in a variety of organic reactions, such as nucleophilic substitution, oxidation reduction and other reactions. Chemists can construct more complex and diverse organic molecular structures by structural modification and derivatization, which contributes to the development of organic synthetic chemistry and helps to synthesize organic compounds with specific functions and structures.